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Cancermaxxin
Verteporfin drug induced scarless healing with new hair follicles on mice. This new founding can be really big
- Thread starter stressftw
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Or maybe not?
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Looks like the forum's back. There has been more great progress with Dr. Barghouthi's experiment with verteporfin. Hairs look like they're sprouting from harvest locations. I wonder how long it's going to take for this to get widespread adoption by hair transplant surgeons.
folliclethought.com
Donor Hair Healing Study With Verteporfin By Dr. Barghouthi – Follicle Thought
This page will chronicle the verteporfin experimental pilot study being undertaken by Dr. Taleb Barghouthi of the Vertex Hair Clinic. The purpose of the study is to observe the effects of verteporfin injected into FUE surgical extraction wounds. Decreased scarring and/or donor hair follicle...
folliclethought.com
Flamingflaps
Established Member
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Possible. Who wants the cure to be a hair transplant though?
Better than what we currently have, a pill you have to take for the rest of your life, that only slows it down and if you’re unlucky like some of us you can’t even have that because of the sides.
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I’m with you on this one - f’n sides!!!
stressftw
Established Member
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Hairliciously covered some of Verteporfin news in his new video.
One year and few months since i created this topic, i remember in the beggining of the discussion some members(even old ones) here saying how "irrelevant" the idea of scarless healing was in regards of combating hair loss. Lol, innocents.
Well, the whole discussion is still there in the beggining of the thread, and the things i pointed out and mentioned (some of them called it "broscience") are legit happening now. Im really glad Vert discovery is evolving and it's benefits are becoming a real thing for people, we are very close from a major gamechanger. Im glad this thread is somehow alive, even tho i think this forum is a ghost town nowdays.
I will leave a before and after from a telegram group that i wont diclose here, from a guy that is treating his scars off-label with Verteporfin for months now and some of his results:
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It's the only realistic thing. Your follicles shut down and die on dht. At that point you need new follicles. You can prevent it with dht control, but you can only replace missing follicles. Generating new ones with scarless healing would be the ideal solution to the latter, if it worked.
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thats not true. DHT starts a long *** signaling chain with lots of molecules involved like growth and death factors etc. for example it affects stem cells proliferation through the WNT pathway. if you get a drug that modulates that change then you can have as much DHT as you want. that would be realistic. or the idea of degrading either receptor or enzyme locally. however nothing innovative has been done here. its just the same old anti androgen way. no surprise because these kind of drugs are very expensive to research and hair loss is not a lucrative market. In theory if there was more money involved.. the problem is also that many pathways are involved and while getting rid of DHT corrects most of them, doing so individually is very hard as could be seen with the samumed failure. I think the best bet would be a locally acting degrader for both through, androgen receptor protein as well as 5alpha reductase. and there needs to be more research on local delivery and vehicles because if the degrader goes systemic its not worse as finasteride but also not any better.
sadly with Kintor AA coming to market the only people who need such a treatment are those like myself who cannot tolerate androgens due to their baseline low androgenic hormone profile and they do not pose a lucrative market alone to drive forward new innovative drugs
It's the best you will get at this point. Many people have had them and are living happy lives. You either use what's available, be miserable or acceptance.
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so what is the current status on this? honestly I thought it was dead just like anything else but on reddit its currently a bit hyped so im wondering. people here seem rather jaded these days
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Since when? Look it up, hair loss treatment is a holy grail market worth trillions. Men of all ages are desperate to look young, especially today when people marry later than ever, or keep hooking up indefinitely.
The reason we do not have a serious working treatment is the same reason we don't have a reliable treatment for cancer despite trillions spent over decades. We're simply not smart enough to figure it out even when money is no object, and dangerous human experiments are unethical and illegal, which makes every invasive study incredible difficult and expensive.
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are they really though? the actual market is probably around 2-3 billion how many men are running around that are balding and dont even know there is something you can do or do know and just dont care. there is a reason why funding and progress has been so incredibly mediocre in recent years. and finasteride works for most and thus three is no incentive
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But nonetheless medical doctors use that knowledge acquired in dangerous medical experiments.
Is it ethical to use knowledge which has been acquired in special "work camps"?
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Yes