Very Impressive Dermarolling And Minxodil Results - From Tressless

pegasus2

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As i said before I am not advocating for or against needling,same with fina,but DHT is not the only culprit and absolutely is being challenged.Its even challenged by you(Bayer prolactin.smi). Challenged to me means, is not the only cause.Thats why i said,that there are many unknowns.
On a different note a lot of us are counting on you to find the cure.So keep up the good work
Prolactin is downstream of DHT. male pattern baldness literally can't happen without DHT. It's proven beyond a shadow of a doubt
 

Armando Jose

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male pattern baldness literally can't happen without DHT
no, all hairs need DHT to grow. body hair is an example.
scalp hairs have DHT a lot of years before puberty, sebaceous gland need this hormone to make sebum.
Till scientists dont take the idea never we shall advance.....
 

pegasus2

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To be fair he is just not using the right words. From his comment I understand that he's saying that there are other factors taking place, you can argument that it's a downstream effect, but prolactin currently remains to be an additional pathway to be addressed without necessarily altering DHT. I would also consider that the (mainstream) theory has been challenged, not as in being proven wrong but rather incomplete, lacking understanding in all the processes involved and also specially lacking the ability to provide a satisfactory solution.
It has always been known that it's incomplete. I don't think anyone ever thought DHT was the only culprit, there are hundreds of genes involved.
 

300

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It has always been known that it's incomplete. I don't think anyone ever thought DHT was the only culprit, there are hundreds of genes involved.
I have to work for a living,so i cant stay here responding to you.I wish i could.You go on the offensive and then on the defensive.It pays to be humble,obviously you dont know that.Humility is a big thing which obviously you don't know.You re changing your tune now about DHT.My expertise is at a different major not biology as you noticed.But i have some common sense knowledge about hair loss and if i wanna know something all i have to do ask a member and i ll have an answer in a minute.I just took a quick look at the Bayer thread and i could nt get the terms right,as the dog pointed out.No need to get smart or arrogant.I am not competing with you in anything,especially in hair loss theory where i consider you to be an expert.Good luck my brother.
 

pegasus2

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I have to work for a living,so i cant stay here responding to you.I wish i could.You go on the offensive and then on the defensive.It pays to be humble,obviously you dont know that.Humility is a big thing which obviously you don't know.You re changing your tune now about DHT.My expertise is at a different major not biology as you noticed.But i have some common sense knowledge about hair loss and if i wanna know something all i have to do ask a member and i ll have an answer in a minute.I just took a quick look at the Bayer thread and i could nt get the terms right,as the dog pointed out.No need to get smart or arrogant.I am not competing with you in anything,especially in hair loss theory where i consider you to be an expert.Good luck my brother.
Wtf? I think I should just stop posting here as nuanced discource appears to be misunderstood for something else. I didn't mean to be insulting, I'm just giving my opinion on the subject.
 

pegasus2

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Last response of the day.Its one thing to give your opinion and its very different to force you opinion .Pigeon try to be your own man
It's called back and forth discussion bro. Calm down. You can disagree all you want, I was just making sure we were understanding each other's positions
 

300

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Why don't you just let it go Bro?What makes you think i wasn't calm?Its funny i thought the same thing about you ,that you were getting uncomfortable.You lectured me about DHT,etc and now you re gonna lecture me about discussion?A discussion you aiways try to dominate?Dont tell me, nobody told you that before. "I disagree with you?'Who can possibly disagree with you Bro?Who can possibly challenge you?You think very highly of yourself Bro.Who cares?Really.
 

fashy

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Why don't you just let it go Bro?What makes you think i wasn't calm?Its funny i thought the same thing about you ,that you were getting uncomfortable.You lectured me about DHT,etc and now you re gonna lecture me about discussion?A discussion you aiways try to dominate?Dont tell me, nobody told you that before. "I disagree with you?'Who can possibly disagree with you Bro?Who can possibly challenge you?You think very highly of yourself Bro.Who cares?Really.

 

Micky_007

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no, all hairs need DHT to grow. body hair is an example.
scalp hairs have DHT a lot of years before puberty, sebaceous gland need this hormone to make sebum.
Till scientists dont take the idea never we shall advance.....
Fully agree, DHT is important.
 

pegasus2

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no, all hairs need DHT to grow. body hair is an example.
scalp hairs have DHT a lot of years before puberty, sebaceous gland need this hormone to make sebum.
Till scientists dont take the idea never we shall advance.....
Hairs don't need DHT to grow, body hairs need DHT to transition from vellus to terminal, but afterwards it is not needed, simply having testosterone is enough. This means nothing for scalp hair because it's site-specific. There is no DHT at 1 years old when your scalp hair starts growing. If there was then your body hair would start growing too. People who are born without the ability to produce 5-ar2 and DHT don't present with body hair, but they grow a normal head of hair and never go bald. It's pretty clear that whatever the reason, DHT is good for body hair, but bad for scalp hair, and it's not required for scalp hair to grow.
 
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Armando Jose

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Hairs don't need DHT to grow, body hairs need DHT to transition from vellus to terminal, but afterwards it is not needed, simply having testosterone is enough. This means nothing for scalp hair because it's site-specific. There is no DHT at 1 years old when your scalp hair starts growing. If there was then your body hair would start growing too. People who are born without the ability to produce 5-ar2 and DHT don't present with body hair, but they grow a normal head of hair and never go bald. It's pretty clear that whatever the reason, DHT is good for body hair, but bad for scalp hair, and it's not required for scalp hair to grow.
Acording to you, there is not sebum in scalp hairs.

The reality is other, scalp hairs have sebum even in prepubertals
Sebaceous gland need DHT to make sebum and pilosebaceous unit can make itself DHT from cholesterol.
 

pegasus2

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Acording to you, there is not sebum in scalp hairs.

The reality is other, scalp hairs have sebum even in prepubertals
Sebaceous gland need DHT to make sebum and pilosebaceous unit can make itself DHT from cholesterol.
"lowering DHT levels in adulthood had no effect on sebum production. If the gland is rich in the enzyme 5 alpha-reductase-2, it is proposed that the sebaceous gland is either exquisitely sensitive to DHT, requiring only small amounts for normal development and function, or that male levels of testosterone compensate for DHT and maintain normal sebaceous gland activity throughout life. It is also possible that 5 alpha-reductase-1 is the enzyme of the sebaceous gland and is unaffected in the inherited condition and by finasteride."

 

Armando Jose

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"in androgen-insensitive subjects"
;)
there is nothing related to it

Imperato papers are not real

Androgens are vital to our survive, not only in the skin but brain

And the question is about DHT and sebum in persons years before puberty, .... they have sebum in scalp hairs.
 

300

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"in androgen-insensitive subjects"
;)
there is nothing related to it

Imperato papers are not real

Androgens are vital to our survive, not only in the skin but brain

And the question is about DHT and sebum in persons years before puberty, .... they have sebum in scalp hairs.
You are waisting your time.You re not going anywhere with this guy.He so abnoxious its unreal plus he has his cronies following him everywhere downvoting everybody who argues with him.
 

300

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Hairs don't need DHT to grow, body hairs need DHT to transition from vellus to terminal, but afterwards it is not needed, simply having testosterone is enough. This means nothing for scalp hair because it's site-specific. There is no DHT at 1 years old when your scalp hair starts growing. If there was then your body hair would start growing too. People who are born without the ability to produce 5-ar2 and DHT don't present with body hair, but they grow a normal head of hair and never go bald. It's pretty clear that whatever the reason, DHT is good for body hair, but bad for scalp hair, and it's not required for scalp hair to grow.
"I ts called back and forth discussion bro.Calm down".Even Cotcarelis doesnt claim to understand everything,but you do.You search the internet to find even a footnote to support you claims.
 

pegasus2

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"in androgen-insensitive subjects"
;)
there is nothing related to it

Imperato papers are not real

Androgens are vital to our survive, not only in the skin but brain

And the question is about DHT and sebum in persons years before puberty, .... they have sebum in scalp hairs.
You said: "Sebaceous gland need DHT to make sebum"

The paper's conclusions: "male levels of testosterone [may] compensate for DHT and maintain normal sebaceous gland activity throughout life"

You: this is totally unrelated to my claim.

Ok, sure.

"adult male pseudohermaphrodites with 5 alpha-reductase deficiency and a selective decrease in DHT production had sebum production scores identical to normal age-matched males."
 
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pegasus2

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"I ts called back and forth discussion bro.Calm down".Even Cotcarelis doesnt claim to understand everything,but you do.You search the internet to find even a footnote to support you claims.
Sorry for hurting your feelings guy. Do you have anything productive to add to the discussion?
 

pegasus2

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