Studies and real life results can be very different.Hairlosstalk is the real laboratory.This is where you go.Do you still believe that the vaccines will protect you from OMICRON?Maybe, but not to the degree the claimed in the beginning.
Of course it is,that's the whole idea behind it
I have a scar on my scalp, still no hair there after a lot of microneedling despite growing hair everywhere around it. I thought at one point it had gotten smaller, but it was just the new hairs around it covering it. I think true neogenesis is only going to happen with SAG, and even then it's difficult to achieve.
Both, not just one
What,what? are you saying its not true?Read some more studies with people who lost their hair due to burns.You disappoint me because i consider you very knowledgeable in needling.
I am talking about that guy and also people theorizing about that.
It's certainly possible, but we're talking about the Follica and Dhurat protocols here. I think that campfire guy was on benoxaprofen, which many people grew hair on but is now banned. De novo hair follicle generation is possible, but I don't think we are accomplishing that with what we are doing. I think Pigeon is right that we are only bringing back dormant follicles.
I am not arguing this point and who is right or wrong only because needling with min can create subjective opinions.The general consensus is that finasteride or duta works for many people but not needling.It didnt work for me but i have no doubt that works for a few people.
How can we possibly reach a conclusion on that when there are not follow up studies?I n my opinion the DHURAT study was an amateur one with very few subjects,
I think you may have misunderstood. I didn't mean microneedling didn't work for me, it worked very well. I got tons of new hairs, but they weren't dead follicles. As I'm sure you know the hair follicle usually does not die, even for decades, it just remains dormant, only producing an invisible vellus follicle at best. Even after many decades bald men retain the follicles in their scalp with a healthy population of HFSCs. All I meant was that it didn't grow back hair on a deep scar. We can't draw conclusions from that, but we certainly have no evidence of de novo HF generation in humans. Even campfire guy probably didn't destroy the follicles when he was burned. It seems more likely that what we are doing is only waking up existing follicles, which is all that we need since follicles usually don't die in Androgenetic Alopecia. I'd say Cotsarelis agrees with that assessment since he started researching using SAG and FGF9 to achieve true de novo HF regeneration. There would be no reason to use such a dangerous drug if minoxidil could achieve the same thing.
When i responded to Solid Snake i told him that he should do it because it might work.If i gave him my opinion based on personal experience i was gonna say no.I didnt.I didnt misunderstand you at all.You gave us a hint that you had results with needling and min. You hit it right on its head when you taiked about Cotsarelis.You hold the man in high regard,I dont But i used to.
I don't follow your logic, if it worked by creating new HFs then it should work on everyone, right? I'm not sure that it not working on everyone would lend evidence either for or against de novo HF regeneration. Since you brought it up though, why does finasteride work for some and not for others? I would argue that microneedling works for most. In fact, the trials prove this rather conclusively. There can be many reasons it won't work on some people, higher AR expression, less sulfotransferase in the scalp, age, longer duration of baldness, so a smaller cell number, making it harder to bring them back.
Whats so abnormal about my logic?I am not a proponent or opponent of micro needling,I am doing it myself.How can you possibly compare fina and needling?One is a proven drug(I am a user) and the other one came into existence from Dhurat and his dozen subjects.
As i said before I am not advocating for or against needling,same with fina,but DHT is not the only culprit and absolutely is being challenged.Its even challenged by you(Bayer prolactin.smi). Challenged to me means, is not the only cause.Thats why i said,that there are many unknowns.