Very Impressive Dermarolling And Minxodil Results - From Tressless

[cryingariver]

Nanoxidil???? First time i hear of this. ahem::::

1. why isn't everyone using this?
2. is it FDA approved?
3. does it work better?

oh this is funny. So nanoxidil has been out for years apparently. But no conclusive studies have been made. A placebo group wasn't used. Further studies are needed. ..... what the f*** are they waiting for????? do drug companies get off on minoxidil and propecia?????

 

[waynakyo]

For those who have been following this thread closely such as @Pigeon, do you notice a pattern in terms of frequency of rolling and results?

I was shocked to see some good responders are rolling very frerquently, one of them 1mm/day. That somehow does not sit well with me when I think that regeneration is due to healing... makes me think it is minoxidil absorption.

 

[ratty]

Seems 1-1.5mm, 1x/week is the "best" protocol from the success stories I've seen. But to be honest, I think it depends on the person. Some people heal very quick, others don't. Adjust to your personal situation, if you don't heal fast, don't needle every week but every 10-14 days.

Which derma rollers / pens do you recommend?

 

[Derek Clapton]

A cheap electric pen is good enough. Look in the opening post, check what he used.

What's the benefit of electric over manual? It seems from the studies that they go deeper.

I've previously tried using a 1mm once a week and a 0.25mm more often and saw no results, but recently read that studies found 0.6mm to be more effective than 1mm, but then if you use manual it seems it doesn't go as deep, so maybe I need 0.75mm to get the 0.6mm depth.

 

[Remi12456]

I was shocked to see some good responders are rolling very frerquently, one of them 1mm/day. That somehow does not sit well with me when I think that regeneration is due to healing... makes me think it is minoxidil absorption.

Who is it, please?

 

[pegasus2]

For those who have been following this thread closely such as @Pigeon, do you notice a pattern in terms of frequency of rolling and results?

I was shocked to see some good responders are rolling very frerquently, one of them 1mm/day. That somehow does not sit well with me when I think that regeneration is due to healing... makes me think it is minoxidil absorption.

Some people can get results just from increased sulfotransferase expression, which will make minoxidil a lot more effective. Minoxidil doesn't need any help with absorption. Neogenesis comes from healing, but neogenesis is very difficult to achieve. I think what most people are seeing is increased minoxidil response due to upregulation of sulfotransferase, and primarily upregulation of various growth factors and Wnt proteins that occurs each time you needle

 

[Kev123]

Honestly this whole micro needling and minoxidil stuff is really letting me down. I don't see sh*t in regrowth, after over a year. I'm maintaining, however, i do believe i am now thinning more in some areas. this is starting to piss me off. All these people with results... i don't get it. i'm doing needling once every 2 weeks. i think i'll up it to once a week.

You may not want to read this, and sorry if you tried it already, but what about adding finasteride or dutasteride orally?

 

[Xenophon]

no, all hairs need DHT to grow. body hair is an example.
scalp hairs have DHT a lot of years before puberty, sebaceous gland need this hormone to make sebum.
Till scientists dont take the idea never we shall advance.....

Unless you subscribe to the chemical castration theory of hair growth, well then it's not science. It's amazing to me that they still talk about DHT causing hair to fall out. "If you remove DHT, hair grows, therefore DHT causes alopecia." That's the classic science nonsequitur. Here is the same flawed principle that losing weight means to "eat less and move more," simply on account of the observable fact that if you acutely reduce calories, weight is often lost. But this tells you absolutely nothing about what's going on with the underlying condition. Moreover, the results are impermanent or ephemeral as well as detrimental in many ways. Here is a perfect analogy for the parochial science-based reddit way of thinking that attenuates progress in understanding pattern hair loss.

Science is just really really stupid. A company like Reviv basically throws a bunch of peer reviewed papers into a vial and sells it. Each active ingredient is backed by these discrete bits of knowledge in the form of studies. Clever chemistry tricks are used to transport the active ingredients. The last part is actually more like a type of engineering, not science, insofar as it is involves 'making things work' in the material world. But science itself, the epistemological framework, seems woefully ill equipped to understand the first thing about hair loss in terms of the organism and the system. No one in the science business considers pattern hair loss to be a symptom of a non-trivial underlying disease, which is kind of mindblowing. They also wrongly call it 'androgenetic alopecia' and of course the name of a thing always delimits the way we can think about it and devise treatments for it.

 

[Armando Jose]

If DHT & testosterone cause hair loss in men—why does nearly all hair loss in men come during the years when all the data points to a simultaneous decline in DHT & T lvls?

 

[cryingariver]

You may not want to read this, and sorry if you tried it already, but what about adding finasteride or dutasteride orally?

I tried finasteride years ago orally, it fucked with my hormones. I absolutely do not want to go that route again.

 

[pegasus2]

If DHT & testosterone cause hair loss in men—why does nearly all hair loss in men come during the years when all the data points to a simultaneous decline in DHT & T lvls?

It's interesting that it comes when DHT is still high, but prolactin is increasing.

 

[Capone]

If DHT & testosterone cause hair loss in men—why does nearly all hair loss in men come during the years when all the data points to a simultaneous decline in DHT & T lvls?

Obviously hair follicles become more sensitive to it as we age.

 

[pegasus2]

Obviously hair follicles become more sensitive to it as we age.

Just like every other cell in the body. The older it gets the less it can tolerate stress

 

[Jackshtbro]

Just like every other cell in the body. The older it gets the less it can tolerate stress

Can confirm, incel inside me can't tolerate it anymore

 

[Capone]

Just like every other cell in the body. The older it gets the less it can tolerate stress

What about trying to increase autophagy through fasting, intense exercise or supplements?

 

[cryingariver]

What about trying to increase autophagy through fasting, intense exercise or supplements?

In addition to microneedling once every 2 weeks (now recently upped to once per week), minoxidil, biotin pills, MSM pills, and Collagen peptides mixed in a glass of water daily, my hair still looks like it is on life support and dying. Supplements won't do anything. not for me at least.

 

[cryingariver]

Cotsarelis can suck my dick.

 

[300]

Cotsarelis can suck my dick.

He can suck mine too

 

[pegasus2]

What about trying to increase autophagy through fasting, intense exercise or supplements

That couldn't be anything but beneficial in the long run. In the short-term the stress of fasting can cause shedding, but clearing out senescent cells helps healthy cells proliferate. SASP has been associated with Androgenetic Alopecia.

 

[pegasus2]

In addition to microneedling once every 2 weeks (now recently upped to once per week), minoxidil, biotin pills, MSM pills, and Collagen peptides mixed in a glass of water daily, my hair still looks like it is on life support and dying. Supplements won't do anything. not for me at least.

Try bicalutamide 60mg and oestrogel once daily.