Gadgetine

Exploring The Hormonal Route. Hair=life.

SnortingFinasteride

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But Bica doesn’t truly lower testerone it causes up regulating so if you already had reflex from finasteride then bica’s upregulation would probably have a similar effect despite using estrogen.
Bica + Estradiol. Not just Bica alone

Also, I don't believe the whole "upregulation" pseudo-science. It has yet to be proven. Finasteride doesn't cause "reflex" or whatever. Your hair just gets targeted by the remaining DHT that finasteride didnt inbibit
 

BRezende

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Bica + Estradiol. Not just Bica alone

Also, I don't believe the whole "upregulation" pseudo-science. It has yet to be proven. Finasteride doesn't cause "reflex" or whatever. Your hair just gets targeted by the remaining DHT that finasteride didnt inbibit
Soo if you dont belive in the upregulation thing (which theres many cases here in this forum), How can you explain the fact that people lose more hair taking finasteride (70% of DHT inhibited) than when they were not taking 5ari, i.e. 0% DHT inhibited?
also it happen with people who take dutasteride too, do you think the 30% DHT left from finasteride and the 10% DHT from dutasteride, some how, become stronger than the normal baseline?
 

losingbattle88

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Soo if you dont belive in the upregulation thing (which theres many cases here in this forum), How can you explain the fact that people lose more hair taking finasteride (70% of DHT inhibited) than when they were not taking 5ari, i.e. 0% DHT inhibited?
also it happen with people who take dutasteride too, do you think the 30% DHT left from finasteride and the 10% DHT from dutasteride, some how, become stronger than the normal baseline?
Yep. Duta for 1.5 years. 1 drop after ejaculation in the end and hair thinned out FAST and alot despite much reduced hairfall in shower/comb. Once I quit that sh*t hair thinned at a snails pace. Im much better off without finasteride/dutasteride. Even finasteride did the same thing but slower.
 

sg2000

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Yes. I take 8 mg E sublingually

E enanthate half life is 7 days. You should inject once a week, not every 2 weeks
r you taking it for hair only?
Im gonna take 75 mg 3 times a week of cpa…(10 mg daily) im too afraid of stopping cpa all of the sudden
 
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sg2000

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The best dose that worked for me is 12.5mg EOD. Im pretty sure you dont need more (if any at all) with your E dose.
6.25mg EOD did more harm than good in my case.

You dont need to note the volume if you already mentioned the mass. And btw, until you change to every 10 days, dont ask me anything. =D
why every 10 days? My levels were 429 14 days after the previous injection. So maybe my leves were somekinde near 600-500 the first week before dropping to 429 14 days after.Arent these good levels?!
 

SnortingFinasteride

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Soo if you dont belive in the upregulation thing (which theres many cases here in this forum), How can you explain the fact that people lose more hair taking finasteride (70% of DHT inhibited) than when they were not taking 5ari, i.e. 0% DHT inhibited?
They lose more hair on finasteride ? I've never seen such cases. Would that mean that getting off finasteride would make their hair loss stabilize ?

Also, don't forget that the body always tries running on a homeostasis equilibrium. Perhaps finasteride destabilizes that balance ? I have seen people losing hair when switching from finasteride to dutasteride, but that is due to dutasteride taking time to build. We simply just do not know enough about hairloss
 

SnortingFinasteride

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why every 10 days? My levels were 429 14 days after the previous injection. So maybe my leves were somekinde near 600-500 the first week before dropping to 429 14 days after.Arent these good levels?!
AS I've said, enanthate half life is 7 days. When you extend the duration between injections, you are experience higher peaks/ lower troughs.

Your levels are probably fluctuating between 1000+ pg/ml to 400 pg/ml, which is wild
 

sg2000

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AS I've said, enanthate half life is 7 days. When you extend the duration between injections, you are experience higher peaks/ lower troughs.

Your levels are probably fluctuating between 1000+ pg/ml to 400 pg/ml, which is wild
i dont care i have such fluctuations unless it will not be effective for hair...i feel good through the 14 days after the injection
@Almas_NW0 inject een too every 2 weeks and hes fine with hair and everything
 

BRezende

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They lose more hair on finasteride ? I've never seen such cases. Would that mean that getting off finasteride would make their hair loss stabilize ?

Also, don't forget that the body always tries running on a homeostasis equilibrium. Perhaps finasteride destabilizes that balance ? I have seen people losing hair when switching from finasteride to dutasteride, but that is due to dutasteride taking time to build. We simply just do not know enough about hairloss
Yes! a lot people here had lost more hair on finasteride them when they was off finasteride. Soo you think the body is becoming more sensitive to the less amounts of DHT? Soo its like your body is upregulated.
 

SnortingFinasteride

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i dont care i have such fluctuations unless it will not be effective for hair...i feel good through the 14 days after the injection
@Almas_NW0 inject een too every 2 weeks and hes fine with hair and everything
It could effect your hair. Also, you are not Almas, I don't know why you are comparing yourself to him ?
 

SnortingFinasteride

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Yes! a lot people here had lost more hair on finasteride them when they was off finasteride. Soo you think the body is becoming more sensitive to the less amounts of DHT? Soo its like your body is upregulated.
When you put it like that, yes I agree. But what happens when they get off finasteride ? Do they regain what they lost ?

Also, don't forget T exists as well, and it is an adrogen, so it definitely effects hair to an extent. It's just a mess lol
 

SavingMyHair

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DHT is just a trash hormone that in some ppl it will be near impossible to eliminate. Every adrenal androgen is capable to convert in tissue to T and DHT. Even if you have literally 0 T 0 DHT and low 3a diol G in serum you could have high peripheral androgen convertion from DHEA-S or androstenedione. Even if DHEA-S and androstenedione are low, you could be unlucky enough to synthesize most of your T/DHT in your scalp because scalp has many androgen receptors and if you add that in top of that those receptors on balding men especially young ones are very sensitive, you have the formula for the disaster. 3a diol G could sound like it is a good test to see peripheral androgens but even that is not enough to really see what is happening on your scalp specifically unless you do a biopsy on different zones of your scalp. Same goes for the skin or the organ you'd like to know.
 
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BRezende

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DHT is just a trash hormone that in some ppl it will be near impossible to eliminate. Every adrenal androgen is capable to convert in tissue to T and DHT. Even if you have literally 0 T 0 DHT and low 3a diol G in serum you could have high peripheral androgen convertion from DHEA-S or androstenedione. Even if DHEA-S and androstenedione are low, you could be unlucky enough to synthesize most of your T/DHT in your scalp because scalp has many androgen receptors and if you add that in top of that those receptors on balding men especially young ones are very sensitive, you have the formula for the disaster. 3a diol G could sound like it is a good test to see peripheral androgens but even that is not enough to really see what is happening on your scalp specifically unless you do a biopsy on different zones of your scalp. Same goes for the skin or the organ you'd like to know.
i remember you you had diffuse thinning as me and you was trying HRT+bica+oral duta every 2 days + oral minoxidil, you didnt recover your hiar? did you ever tried to block the adrenal androgens with dexamathesone or something like that?
 
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