Dutasteride

[dante80]

This is great news guys, we have been hearing this for well over a year...now it will be here! Hopefully I will response to Dutasteride.
:roll: Quick question guys, I know that finasteride and dutasteride works similiarly, if finasteride didn't work for me, will I have a less chance of dutasteride working for me? Thanks for any info!

Keep on fighting the good fight!

 

[Troymaclure]

This is great news guys, we have been hearing this for well over a year...now it will be here! Hopefully I will response to Dutasteride.
:roll: Quick question guys, I know that finasteride and dutasteride works similiarly, if finasteride didn't work for me, will I have a less chance of dutasteride working for me? Thanks for any info!

Keep on fighting the good fight!

depends how you determine that finasteride didn't work for you; if you are one of those who claims that finasteride made things worse for you then it must therefore stand to reason that Dutasteride would only make things *even* worse...thats why i can't understand people who complain that finasteride destroyed their hair and ate their hairline and can't wait to get on dutasteride :roll:

HOWEVER....if you simply feel that finasteride just has not worked too well at maintaining your hair, as opposed to it being to blame for making it worse, then dutasteride should be more effective at keeping DHT levels suppressed for longer and to a higher degree, so yes there should be a greater chance of maintaining your hair with dutasteride

 

[RalphyWiggum]

This is pretty much due to skewed perceptions and blunt stupidity. Only in very, very rare cases can finasteride make your hair worse and in those cases we know you aren't just going to see your hair get worse. You are going to see a major increase in acne and secretion of oil. RHA as they call it will not just cause your hair to get worse alone. So 99% of those who are just claiming propecia made there hair worse and ate their hairlines really didn't repond to the drug. They may have a new lease on life with Duta they may not! We will see soon enough.

 

[Axon]

This is pretty much to due to skewed perceptions and blunt stupidity. Only in very, very rare cases can finasteride make your hair worse and in those cases we know you aren't just going to see your hair get worse. You are going to see a major increase in acne and secretion of oil. RHA as they call it will not just cause your hair to get worse alone. So 99% of those who are just claiming propecia made there hair worse and ate their hairlines really didn't repond to the drug. They may have a new lease on life with Duta they may not! We will see soon enough.

I agree ralphy. I attribute it to anger and frustration - people are pissed, and they DEMAND a reason that they're going bald beyond the fact that their hair is prone to male pattern baldness. So blaming Finasteride or Rogaine is a natural step.

 

[RalphyWiggum]

Well I think it is safe to say the percentage of people who are not having good results is going to be higher in these forums. That is, after all, the reason most people come here. To learn more about male pattern baldness and to modify their treatment of it. Those who are good responders and can just pop a pill and be done with it are the same people who wouldn't be bothered to come here. Simple as that!

 

[Axon]

Ah...I'm a good responder and I still spend a lot of time here...but I just like to read the wild theories.

 

[RalphyWiggum]

Well then you and I are in the minority (although this forum seems to be the best about the whining and complaining issue). I am talking about in general though. I get really annoyed with Hairlosshelp.com. People there are constantly crying, "the sky is falling."

 

[Troymaclure]

well ralphy...i hate to say i agree with you...but i agree with you....the whole finasteride eating people's hairlines stuff winds me up sometimes, and HLH sometimes seems to be a place where one person says something bad is happening, or a particular product is causing hair to thin or fall out, and then all of a sudden about 15 others realise the same thing is happening to them and has been for some time, and within a week it becomes like some accepted side effect of a certain treatment or something...does get a bit tiresome sometimes

 

[Axon]

well ralphy...i hate to say i agree with you...but i agree with you....the whole finasteride eating people's hairlines stuff winds me up sometimes, and HLH sometimes seems to be a place where one person says something bad is happening, or a particular product is causing hair to thin or fall out, and then all of a sudden about 15 others realise the same thing is happening to them and has been for some time, and within a week it becomes like some accepted side effect of a certain treatment or something...does get a bit tiresome sometimes

Yeah dude. Then they post pictures and their hairlines are better than MINE! Maybe it's because I had bad acne earlier in my life and I'm more accepting of uncontrollable physical faults, but these guys just FREAK over very little. Makes me wanna slap someone...

 

[RalphyWiggum]

LOL, Matt g being the newest addition this idiocy. I mean come ON!!!!

There is absolutely nothing wrong with that man's hair and to read his posts you would think he looked Danny Devito. Even his signature suggests his hair is just horrible:

"being bald sucks, Now I know why newborn babies cry!"

Could a quote be any less relevant to a person's situation? So he doesn't have perfect density on top...he's not in the minority. Most people are in between Brad Pitt and Dr. Phil. Deal with it.

The best point being, none us will probably ever get to Brad Pitt density but at least we will neve get to Dr. Phil Density either (lol zero density). That is thanks to finasteride, monoxidil, tricomin, and nizoral. Like I posted somewhere a while back our ancestors would kill to be in our position right now with duta on two months away.

 

[Andy_G]

Ralphy,

I'm the idiot you're talking about.

I agree that I wrongly assessed my hairloss situation to some extent. But if you really had taken a closer look at my May picture you should have seen that I certainly didn't have the perfect top back then. Most people think I'm a Norwood 1 or 1.5 now.

You will see that generally spoken, I have made progress since May, mostly in my frontal area. I considered myself a Norwood 2 when I started posting there and chose my profile at the beginning of the year. I also used the term "diffuse thinning" in my profile, "general thinning" would have been more appropriate. So yes, I was wrong there because I thought both were more or less synonyms.

In your post, you give the impression that I'm a finasteride hater. :roll:
Well, quote me. Just give me one quote where I blame finasteride for causing extra loss. Besides that, I have always said that I didn't get any annoying side effects from taking finasteride (I'm taking 5mg a day by the way). I guess I'm one of the happy few if I may believe everyone else.
What I did say is that finasteride seems to work better in front than at the back for me, which is rather uncommon. I consider finasteride (together with minoxidil) the most valuable thing in my extensive regime.

To avoid apparent misunderstanding, I have removed this quote "being bald sucks, now I know why newborn babies cry". It was just supposed to be something funny, I read this quote some time ago. In my profile it used to say "Norwood 2", so how could I have been bald then ? I thought it was quite clear to everybody that this was just a funny quote, nothing more than that. javascript:emoticon('') Surprised


Andy

 

[Axon]

Ralphy,

I'm the idiot you're talking about.

I agree that I wrongly assessed my hairloss situation to some extent. But if you really had taken a closer look at my May picture you should have seen that I certainly didn't have the perfect top back then. Most people think I'm a Norwood 1 or 1.5 now.

You will see that generally spoken, I have made progress since May, mostly in my frontal area. I considered myself a Norwood 2 when I started posting there and chose my profile at the beginning of the year. I also used the term "diffuse thinning" in my profile, "general thinning" would have been more appropriate. So yes, I was wrong there because I thought both were more or less synonyms.

In your post, you give the impression that I'm a finasteride hater. :roll:
Well, quote me. Just give me one quote where I blame finasteride for causing extra loss. Besides that, I have always said that I didn't get any annoying side effects from taking finasteride (I'm taking 5mg a day by the way). I guess I'm one of the happy few if I may believe everyone else.
What I did say is that finasteride seems to work better in front than at the back for me, which is rather uncommon. I consider finasteride (together with minoxidil) the most valuable thing in my extensive regime.

To avoid apparent misunderstanding, I have removed this quote "being bald sucks, now I know why newborn babies cry". It was just supposed to be something funny, I read this quote some time ago. In my profile it used to say "Norwood 2", so how could I have been bald then ? I thought it was quite clear to everybody that this was just a funny quote, nothing more than that. javascript:emoticon('') Surprised


Andy

Oh, you're no Fina hater...but just the level of freakage that comes from some people staggers me. You're actually not that bad Andy.

BTW, the hair looks great.

 

[Andy_G]

Thanks Axon.

Everybody should be thankful that finasteride is available (and dutasteride soon). I think only a very small percentage of people are able to keep their hair with just minoxidil.

Finasteride was the first real "prevention" and "maintaining" tool (at least for a couple of years in a larger number of persons). Hopefully dutasteride will proof to be even more succesful. I honestly have faith in that (--> look at the half life of duta & extra DHT inhibition) and asap I'll switch to dutasteride.

Look, I don't say that nobody experiences side effects. F.i Kevin has problems with larger doses of finasteride.

I have my doubts with 90% of the people who say that finasteride made their hairloss worse because I personally think that those are people for whom finasteride just doesn't inhibit enough DHT. So, their hairloss progresses (maybe even a little slower) and they conclude that this is the fault of finasteride. Dutasteride may be their "safety belt".

Of course, there are cases of Telogen Effluvium caused by finasteride, but these are rather rare and I think some people seem to confuse shedding cycles with Telogen Effluvium.

 

[Axon]

Thanks Axon.

Everybody should be thankful that finasteride is available (and dutasteride soon). I think only a very small percentage of people are able to keep their hair with just minoxidil.

Finasteride was the first real "prevention" and "maintaining" tool (at least for a couple of years in a larger number of persons). Hopefully dutasteride will proof to be even more succesful. I honestly have faith in that (--> look at the half life of duta & extra DHT inhibition) and asap I'll switch to dutasteride.

Look, I don't say that nobody experiences side effects. F.i Kevin has problems with larger doses of finasteride.

I have my doubts with 90% of the people who say that finasteride made their hairloss worse because I personally think that those are people for whom finasteride just doesn't inhibit enough DHT. So, their hairloss progresses (maybe even a little slower) and they conclude that this is the fault of finasteride. Dutasteride may be their "safety belt".

Of course, there are cases of Telogen Effluvium caused by finasteride, but these are rather rare and I think some people seem to confuse shedding cycles with Telogen Effluvium.

I'm told Telogen Effluvium is reversible, and TOTALLY different from pattern balding. I just don't see how people confuse the two...

 

[Bryan]

Concerning the 2-year dutasteride study for BPH:

It's interesting that there was not a single mention of hair regrowth anywhere in that study which I posted about a few days ago, even though they had that fairly extensive discussion of side-effects. In fact, the word "hair" was not mentioned once in the entire article.

I'm going to write to Dr. Claus G. Roehrborn, who was the lead author/investigator, and ask him if any new hairgrowth was noticed in any of the balding subjects in that trial after 2 years, and if so, how significant it was. If he replies to me, I'll report here whatever he says.

Bryan

 

[RecedingBoy]

This is pretty much to due to skewed perceptions and blunt stupidity. Only in very, very rare cases can finasteride make your hair worse and in those cases we know you aren't just going to see your hair get worse. You are going to see a major increase in acne and secretion of oil. RHA as they call it will not just cause your hair to get worse alone. So 99% of those who are just claiming propecia made there hair worse and ate their hairlines really didn't repond to the drug. They may have a new lease on life with Duta they may not! We will see soon enough.

I agree ralphy. I attribute it to anger and frustration - people are pissed, and they DEMAND a reason that they're going bald beyond the fact that their hair is prone to male pattern baldness. So blaming Finasteride or Rogaine is a natural step.

i don't blame finasteride, but I am keeping my eye on minoxidil. I'm not so sure minoxidil cannot make hairloss worse.

 

[Axon]

This is pretty much to due to skewed perceptions and blunt stupidity. Only in very, very rare cases can finasteride make your hair worse and in those cases we know you aren't just going to see your hair get worse. You are going to see a major increase in acne and secretion of oil. RHA as they call it will not just cause your hair to get worse alone. So 99% of those who are just claiming propecia made there hair worse and ate their hairlines really didn't repond to the drug. They may have a new lease on life with Duta they may not! We will see soon enough.

I agree ralphy. I attribute it to anger and frustration - people are pissed, and they DEMAND a reason that they're going bald beyond the fact that their hair is prone to male pattern baldness. So blaming Finasteride or Rogaine is a natural step.

i don't blame finasteride, but I am keeping my eye on minoxidil. I'm not so sure minoxidil cannot make hairloss worse.

I didn't mean you, RB. But there are many who DO blame Fina.

 

[Edge]

Off Label Avodart

My Doctor here in Canada was well versed and understood Propecia when I showed up at his office 8 months ago and asked him to help me out of this depresion called thinning hair...he was cool and prescribed it for me for a few months until I could decide if I wanted a year long prescription...which I did and I have one now.

When it does hit the street how do I get him to prescribe Avodart for me?

Odds are he doesn't follow these newsgroups like I do...why would he!

If it is not written in any official looking, recent educational papers, how do I help him get an understanding of what it is and why I want it so much?

How do you guys plan on going about educating your doctors?

Also, any guesses as to the price vs Propecia?

THX

Edge

PS- Any body now of a doctor that has already said sure they would prescribe it for you, maybe my doctor can give him a call!

 

[Bryan]

Concerning the 2-year dutasteride study for BPH:

It's interesting that there was not a single mention of hair regrowth anywhere in that study which I posted about a few days ago, even though they had that fairly extensive discussion of side-effects. In fact, the word "hair" was not mentioned once in the entire article.

I'm going to write to Dr. Claus G. Roehrborn, who was the lead author/investigator, and ask him if any new hairgrowth was noticed in any of the balding subjects in that trial after 2 years, and if so, how significant it was. If he replies to me, I'll report here whatever he says.

Bryan

Well, my friend "Soulpt" beat me to it! Because he's not registered here, he asked me to post this for him:

So everyone knows I took it upon myself to contact a doctor involved in the BPH trials of Dutasteride/Avodart. My question(s) and his reply are reprinted from the email I received today. I forwarded him some follow up questions regarding any "outstanding" responders. Hopefully he will respond with some positive comments.

Soulpt asked: "Dr. Roehrborn, I am aware that you were involved in testing a product recently approved by the FDA for BPH. As I am sure you are aware the chemical (dutasteride) has completed phase 2 testing for hair loss as well. I was hoping that you could answer a couple of questions for me regarding the product.

In your testing of Avodart for Glaxo-Wellcome did you notice any significant side effects of scalp hair growth for the test subjects? I am fully aware of the side effects and risks listed by GW but was curious if you observed this in any of the test subjects. Thank you in advance for your reply."

Dr. Roehrborn replied: "As in the case of finasteride, patients on dutasteride reported spontaneously increased growth of scalp hair. But, since this was not a main focus of the study, not systematic attempt was made to capture this."

 

[Webbie]

Edge...

My doctor said that he will indeed prescripe Duta for me (before hair loss trials) if and only if the post-marketing trials that are performed prove that it is "safe". He feels the medical trials done before a drug is marketed are usually small and biased, so he's waiting for the trials that are conducted independently after Duta's release (much like with Propecia).