end of baldness.they figured it out all.

[Sparky4444]

Incorrect.

2014 was the projected date for Aderans until it got shelved by the corporate pigs that ran ARI.



RIDICULOUS!

Replicel wasn't begging, Histogen pretty much is though! And what's wrong with Shiseido giving Replicel nearly 30 million dollars to further fund the trials??



Forget percentages. None of us should be complacent with 'oh, you'll have 20% more hair.' Thats bullsh*t. What happens if youre slick bald? What's 20% more from ZERO hairs? I'll be satisfied when they say 'We can give you as many follicles and terminal hairs as you want'.

Anything less than THAT is not good enough!

2014 -- correct -- I was being conservative saying 2015...

Replicel -- Being Canadian, do you watch Dragons Den?? You see these poor bastards making their case for investment ... RepliCel is doing the same thing, on a MUCH larger scale...and nobody in North America is biting?? How much did L'Oreal invest in their Hypoxic whatever??? For me, all the noise RepliCel is making with their announcements and notices, etc,etc, doesn't trick well for me...theirs billions at stake here, they shouldn't have to make all this noise to attract attention if they "had it"...whatever they have is unproven....that's my opinion if I was a betting man

Percentages?? Sure, I hear ya...but at the moment, I'd take 60% on my back and dense up my front and top with hair transplant, even if it was a standard FUE and not PiloFocus...

...either way -- RepliCel is dead for me...plain and simple...Unless Follica comes out of the closet and stuns us all, those that are in their early 40's and facing NW4, we're screwed except for PiloFocus hope

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the other troubling thing is that RepliCel were going to start their Phase IIb trials 2 YEARS AGO...that was scratched...2 years lost...I applied for that...too much gamesmanship here with this company...besides, hairloss isn't the only thing they're working towards.

 

[benjt]

I know that I'm on Sparx4444's ignore list. This is not meant as a reply to him but to clear up things for the others.

...If you're getting excited about RepliCell, then you can afford 5 years of waiting...most of us don't have 5 years to waste...

Nonetheless, either they or Follica will be the first ones to provide any regenerative treatment. As things stand, there is no better option than to wait for those years until RepliCel or Follica will be available.

and the fact they're crawling around the globe begging for places to further their research just doesn't give me any confidence that this thing even works...period...

Yeah, of course. Sparx4444 also thought that RepliCel is a "JOKE" and "rats" because they release trial data 24 months after the trials which is commonplace for almost every clinical trial. Even if not released, those data are almost always collected.
They aren't going begging anywhere, and arent going anywhere to "further their research". Shiseido serves as a distributor for SEA, because RepliCel as an R&D company has no distribution resources. The continuing Phase IIb trials right now are mandatory to acquire approval for a treatment by the authorities such as the FDA and regional counterparts in Europe and elsewhere. In case such approval is necessary, at least - some said that this approval is not necessary in the case of Follica because their treatment will only be available under doctoral supervision. Either way, as can also be read on Wikipedia, Phase IIb and III are carried out to make sure that a treatment does not only work, but also that it is safe. Thus, no company will dump phase IIb trials even if efficacy was already established.
Sparx4444 also continues to ignore the mid-trial data from phase I/IIa, which showed 12% density increase after 6 months which can be obtained here.

and when I mean "works", I mean grow the hair, it stays and you have a cosmetic difference -- anything less than 60% regrowth will not be good enough for most...

The 12% regrowth were after only 6 months. We don't know yet if after another 6 months additional regrowth can be achieved or not, or if the 12% stay. That is, by the way, exactly what the 24 months post-trial data is for. To see if it stays or not and if there are long-term risks.
As for "what is good enough" everyone has to decide for themselves. If I can get a shot every two years to maintain and not use any minoxidil or finasteride, I'd be quite happy. If each shot fills in a little bit more hair, I'd be even happier, and 12% in just one shot ain't too bad. Not perfect, but - at least in my opinion, everyone has to determine that for themselves - quite an improvement.

...whatever they have is unproven....

Yeah, if you ignore the phase I/IIa results then they're unproven. But for everyone else who does not selectively ignore clinical data when it does not fit their personal views, they're not.

Given the history of male pattern baldness maybe we should wait until we see everything working the whole process start to finish maybe replicated by someone else before we proclaim male pattern baldness is history.

We don't even know yet whether Follica or RepliCel achieve full regrowth with their treatments or only limited regrowth, e.g. if RepliCel can only give you regrowth once and that's it. For example only on areas that are thinning right now or haven't been completely dead hair-wise for a long time. At least the limited regrowth is certain. The potentially limited effect of at least RepliCels treatment was convincing enough for Shiseido to sign a 30 million dollar contract with RepliCel which gives Shiseido exclusive distribution rights in SEA. Seems Shiseido is convinced of the effect that RepliCel achieves. That makes me quite optimistic that at the very least, limited but reliable regrowth can be achieved with RepliCel's solution. If any more than these 12% can be achieved with long-term treatment, is yet to be seen and will be established with the phase IIb trials. Whether the gains from the short-term phase I/IIa trials actually stay will be seen at the presentation of the 24 month post-trial data.

Well that's good news I guess! What the **** happened to Histogen though? They've gone awfully quiet!!

I haven't followed them at all, so I can't say. But at least the approach of Follica and RepliCel is known and has been confirmed to work.

 

[hellouser]

2014 -- correct -- I was being conservative saying 2015...

Replicel -- Being Canadian, do you watch Dragons Den?? You see these poor bastards making their case for investment ... RepliCel is doing the same thing, on a MUCH larger scale...and nobody in North America is biting?? How much did L'Oreal invest in their Hypoxic whatever??? For me, all the noise RepliCel is making with their announcements and notices, etc,etc, doesn't trick well for me...theirs billions at stake here, they shouldn't have to make all this noise to attract attention if they "had it"...whatever they have is unproven....that's my opinion if I was a betting man

Percentages?? Sure, I hear ya...but at the moment, I'd take 60% on my back and dense up my front and top with hair transplant, even if it was a standard FUE and not PiloFocus...

...either way -- RepliCel is dead for me...plain and simple...Unless Follica comes out of the closet and stuns us all, those that are in their early 40's and facing NW4, we're screwed except for PiloFocus hope

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the other troubling thing is that RepliCel were going to start their Phase IIb trials 2 YEARS AGO...that was scratched...2 years lost...I applied for that...too much gamesmanship here with this company...besides, hairloss isn't the only thing they're working towards.

You can be pissed all you want and believe me, I've shown more rage and obsessed fury on BTT more than most guys... if not the most but unless these guys, Replicel, Histogen and all of them hear our frustration its going to fall on deaf ears. I hope they're reading the forums though, because the amount of time some of them have taken is disgusting.... Follica should have been finished a long time ago. Aderans took WAY too long. Histogen is constantly at a stand still. Replicel is dicking around with other ventures non-hair related... and uh... well, thats all we got.

 

[Sparky4444]

You can be pissed all you want and believe me, I've shown more rage and obsessed fury on BTT more than most guys... if not the most but unless these guys, Replicel, Histogen and all of them hear our frustration its going to fall on deaf ears. I hope they're reading the forums though, because the amount of time some of them have taken is disgusting.... Follica should have been finished a long time ago. Aderans took WAY too long. Histogen is constantly at a stand still. Replicel is dicking around with other ventures non-hair related... and uh... well, thats all we got.

yep...if anything, even though Follica has been equally frustrating, strangely enough I prefer their approach of keeping their cards closer to their chest -- a sign of confidence...or a sign they're screwed and they know it...but I'll go with the former seeing is that's what my instinct tells me

 

[Deadman1]

Are you guys still expecting a cure for male pattern baldness? Don't be ridiculous. Billions of dollars have been thrown at breast cancer research alone and we are no closer to a cure than we were 40 years ago. If there were a cure for male pattern baldness, all the free grant research money would disappear. Why would someone put themself out of a job?

 

[Sparky4444]

Are you guys still expecting a cure for male pattern baldness? Don't be ridiculous. Billions of dollars have been thrown at breast cancer research alone and we are no closer to a cure than we were 40 years ago. If there were a cure for male pattern baldness, all the free grant research money would disappear. Why would someone put themself out of a job?

The one's who found the cure would never have to worry about another job for the rest of their lives...I doubt they'd give a rats-*** about anybody else and putting them out of a job

 

[bushbush]

Are you guys still expecting a cure for male pattern baldness? Don't be ridiculous. Billions of dollars have been thrown at breast cancer research alone and we are no closer to a cure than we were 40 years ago. If there were a cure for male pattern baldness, all the free grant research money would disappear. Why would someone put themself out of a job?

Is breast cancer male pattern baldness?

 

[Sparky4444]

...here we go again...male pattern baldness is NOT A DISEASE!!! IT IS A CONDITION!!! Breast cancer kills millions and millions of women ....ummmmm, male pattern baldness DOES NOT KILL YOU!! Despite whatever BS research some will refer to showing that balding men are more prone to developing "this or that"

 

[Deadman1]

...here we go again...male pattern baldness is NOT A DISEASE!!! IT IS A CONDITION!!! Breast cancer kills millions and millions of women ....ummmmm, male pattern baldness DOES NOT KILL YOU!! Despite whatever BS research some will refer to showing that balding men are more prone to developing "this or that"

My point exactly. Millions of millions of people die from breast cancer. Billions and billions of dollars thrown at research, yet still no closer to a cure than we were 40 years ago. What makes anyone think there will be a cure for male pattern baldness?

 

[hellouser]

Are you guys still expecting a cure for male pattern baldness? Don't be ridiculous. Billions of dollars have been thrown at breast cancer research alone and we are no closer to a cure than we were 40 years ago. If there were a cure for male pattern baldness, all the free grant research money would disappear. Why would someone put themself out of a job?

Breast Cancer funding affects male pattern baldness research? I didn't know that.

 

[Sparky4444]

I think the point has to do with the opinion that we're not very smart as a species...a lot of points for that argument -- you don't have to look any further than some contributors on this thread as proof...present company excluded, of course

 

[hellouser]

I think the point has to do with the opinion that we're not very smart as a species...

Of course we're not. We're borderline retarded. We can't even come together and agree on electing an individual that is smarter than us... George W. Bush being president... TWICE.

But that's not relevant to hair loss, we've obviously done some incredible things so far and now we just need to put our latest findings in practice and show that we can grow as many follicles with hair as we want... which means:

Men privileged to have hair will no longer be privileged with having us baldies out of the way and move up the ladder. GAME OVER, ASSHOLES.

 

[karankaran]

I do t like when people bring in the cancer card into play. Cancer research is perhaps the biggest failure in the history of civilization. Nothing absolutely nothing has come even close to a cure, only pathetic treatments to fill the pockets of the corporate Jews.

The biggest f****** failure in the history of civilization is not cancer research but reproduction of people like you, who are filled with hatred and conspiracies against a group of people they are biased against. I know you will get plenty of support here but that is what is truly pathetic about people like you and your supporters. What is your contribution to the world? Do you even have a god damn academic degree to begin to talk about how academia works. Do you think we have some sort of a secret agreement here which we sign when we enter the field of scientific research? Every time i look at newspaper and see a poll of all hate filled crackpots as 11% of the pop and i wonder where that 11% lies. Oh, now i see. You guys have turned HairLossTalk.com new research section into a playground of your conspiracy theories and i bet that you will be the first in line to get a cure. Every single trending topic , except for this, is nothing but a ego blast from people who believe scientists are a fraud and do not knowingly invent a cure to get the freaking grant money. If you ever knew how people in scientific community earn and how hard we work to get even a simple researcher position , where we have our own lab.

Now i know whats gonna happen , all the rabid dogs of this section will start to pounce on me. I have been keeping quiet Not anymore.. and No, i am not a jew but i have heard this argument before. Bring on your abuses, i have 1000s for every one you hurl at me.

 

[Sparky4444]

I do t like when people bring in the cancer card into play. Cancer research is perhaps the biggest failure in the history of civilization. Nothing absolutely nothing has come even close to a cure, only pathetic treatments to fill the pockets of the corporate Jews.

line crossed...bigtime...

...I think the Moderator will have to be brought in on this one...

 

[hellouser]

I do t like when people bring in the cancer card into play. Cancer research is perhaps the biggest failure in the history of civilization. Nothing absolutely nothing has come even close to a cure, only pathetic treatments to fill the pockets of the corporate Jews.

If you think Jews are running pharmaceuticals like they do Hollywood, you're mistaken. Let me ask you this:

Who would be the real losers if there was hair loss cure? Here's a pretty solid list of everyone involved in treating hair loss:

--------------------------------------------------------------------------

Merck/Finasteride
It'll probably still be on the market for those who cannot afford a greater means of a solution but it will be a GREAT way to prevent hair loss. Only a superior preventative measure could make finasteride irrelevant although I do hope that day comes soon as I despise the thought of potentially sacrificing erections, libido or having gyno for a pill and only to PREVENT hair loss.

Cosmo Pharmaceuticals
Once CB is released, finasteride should be obsolete. If its as safe as they claim, it will be the gold standard in prevention.

Rogaine and generic Minoxidil producers
I can only see Rogaine being used in the future IF Cosmo's CB doesn't pan out.

Snake Oil Salesman
Guys like 'Dr.' Nigam should all be in jail, so whatever happens to these scumbags will be a major breakthrough of its own.

Hair Transplant Doctors
I actually don't see these guys going anywhere. FUT will probably still have its place as you can combine it with FUE, but once Pilofocus is out, FUE should be obsolete. But hair transplant doctors will still have their place for smaller procedures or for guys with minimal hair loss that won't require an extensive treatment like stem cell therapy.

Nizoral
It's actually for dandruff so it will remain on the market. However, if a cure for hair loss if found... their market will expand. Score for them!

Manufacturers of Shampoo (any kind, for hair loss or other)
These guys will benefit just like manufacturer of Nizoral, more people to sell to.

Histogen (if they ever get off their *** and try to release the product)
These guys will be a superior maintenance/prevention product to both CB and Finasteride. HSC is actually more of a growth stimulant so it should play nice when compounded.

--------------------------------------------------------------------------

Here's something else to consider; once stem cell therapy for hair loss becomes reality, there's no guarantee that new follicles will be DHT resistent. A product like CB could still have its place in order to prolong the life of new follicles from DHT's effects. I say this ONLY if stem cell therapy is going to cost an arm and a leg. But the major problem for many of you is that you guys live in USA and have the FDA completely fvcking you in the *** with restrictions on biotechs, which is incredibly stupid considering how it could affect the economy (every revenue stream counts!). Also it needs to be said that you dont need the entire current industry to dwindle and fail in order for a cure to succeed... the two CAN and should coexist and I think they most definitely will.

There's a LOT to gain with a hair loss cure... it'd basically create an entire new industry with restoration and significantly increase revenue in maintenance, care, styling, etc. Hell, I'm sure some hair stylists wouldn't mind more clients.

There's no 'Jew' holding back a cure. The only people that subconsciously don't want a cure are the ones that don't need it and have hair; their high social standing would be diminished, the playing field would finally be even. Fred Hirsch's Positional Good theory would no longer be relevant to hair loss and the assholes in society that have been privileged with humiliating us for long enough would finally STFU. THAT'S who I want to see suffer... I want the social tables to turn. I'm tired of being at the bottom of the totem pole... I know exactly where I currently stand in society and its riddled with disrespect

 

[LayZ]

I do t like when people bring in the cancer card into play. Cancer research is perhaps the biggest failure in the history of civilization. Nothing absolutely nothing has come even close to a cure, only pathetic treatments to fill the pockets of the corporate Jews.

I think your brain squeezed outta them dermarolling holes and then yer jizzle dripped back in yer empty dome...

 

[c_super2]

People are entitlted to their opinions. I hope desperateone is not banned for it. But I think the discussion should stick to hair loss. Also, lots of JEws are bald. Im sure they want a cure as bad as we do.

 

[abcdefg]

It is tough to be optimistic about a cure especially when pushed for a guess on the timeline. Looking at the past male pattern baldness has had a pretty tough one so its still hard to be totally optimistic about this until we see something really concrete from it all. There really are not all that many diseases or conditions that have true cures I mean how many things are really curable in the sense they can be fixed 100 percent reliably? Not very many and its for good reason the stuff just aint easy to do. The body as we all know is a seriously complicated thing.

 

[hellouser]

It is tough to be optimistic about a cure especially when pushed for a guess on the timeline. Looking at the past male pattern baldness has had a pretty tough one so its still hard to be totally optimistic about this until we see something really concrete from it all. There really are not all that many diseases or conditions that have true cures I mean how many things are really curable in the sense they can be fixed 100 percent reliably? Not very many and its for good reason the stuff just aint easy to do. The body as we all know is a seriously complicated thing.

I can't name a single disease or condition that has been cured.

 

[2young2retire]

fred psychological disorders can get treatment you know.

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please stay on topic. they are close with the cure homies.