end of baldness.they figured it out all.

[swingline747]

even if they grow these little puppies in a dish they still have to be planted into your head. You will still need a surgeon to do this, no?
I get the entire "unlimited supply" of hairs and all but really you can still get a botched job, semi high failure rate etc. I personally wait for the day a nice topical comes out that has ZERO sides except growing you back to much hair on your head.

 

[I.D WALKER]

Is this update from the 9/13/2013 article in The Scientist or something else?

 

[Sparky4444]

Getting back on the topic from before derailing: Do you have any timeline/schedule information for Follica? I couldn't find anything.

You're the one who derailed this thread by attacking my reply...holy jeezus your ARE one big delusion...

To everyone else...

...LISTEN...there is NOTHING TO DISCUSS HERE AT PRESENT when it comes to ACELL...I applied for Phase 2 trials over 1.5 years ago NOW!! And NOW they're prepping for Phase 2 trials??? Gimme a break...Rewind two years -- they were on Phase 2 and targeting Phase 3 completion by 2015, or somewhere's near that...They are behind by 5 years now??!!

...In my opinion, ACELL is not working as effectively as THEY thought it would...How else can you explain this lapse?? So although their research is not dead-in-the-water, I would not put any hope into this because you're gonna be on roller-coaster for 5 years...I ain't putting myself through that...plus I'll be damn near 50 by that time...screw that noise

- - - Updated - - -

...as for FOLLICA, there's radio silence....nothin'...they can come out in a week and blow the doors off everyone, or they can be quiet for another year or two before Dr. C says a peep...

ACELL and FOLLICA, while not dead, are not players at the moment...other than PiloFocus, I don't know who are the players right now...

- - - Updated - - -

Just this:

http://www.puretechventures.com/pipeline.php

Apparently Phase II trials are complete in EU (unsure if theyre IIa or IIb or if there were ever two sets of Phase II trials like Histogen's IIa/IIb)

..based on that graphic, ACELL will be more viable before these guys...OMG, this is nuts...wtf is going on??

I've always maintained that a "breakthrough" will stand on it's own -- it will be a spark that will come and it will be more cut-and-dried than all this BS, that will only give as much hair coverage as Linus from the Peanuts Gang

- - - Updated - - -

..in fact, it's been well over 1.5 years since I applied for ACELL phase 2...it's been 1.5 years since I was going to do a hair transplant with Rahal, and the ACELL thing was wayyyyy before that...more like over 2 years now...and I believe it was Phase 2b, but i could be wrong on that..

 

[I.D WALKER]

Fellows verbal engagement is a choice . Please try to remember that from now on. Aside from the chronic exchange of barbs I still appreciate the diverse perpectives and news reported.

 

[benjt]

You're the one who derailed this thread by attacking my reply...holy jeezus your ARE one big delusion...

Of course, Sparx4444. Of course I derailed it. Not you with making discrediting statements without any backing whatsoever. And as it turns out, you even mixed up companies when discrediting, see below.

...LISTEN...there is NOTHING TO DISCUSS HERE AT PRESENT when it comes to ACELL...

If you say so, given that you're the leading expert on "scientific method", that must be the case. Though I never claimed any knowledge about ACell.

The funniest thing, though, is that you're the only one discussing ACell. Even when you went aggressive on my post about RepliCel, you referred to ACell:

..you're nuts..and you've been corrected by Hellouser who is exhibiting more insight into ACell than you've shown...

Hellouser did not make a single statement about ACell, neither did I. I did not exhibit any "insight into ACell", nor did he. I presented numbers for RepliCel which you attacked. In my following post, I explicitely pointed out that I have not talked about RepliCel and asked you whether you noticed that we did not talk about ACell.

And now a whole post about ACell again, while the rest was discussing Follica and RepliCel. Nobody except you even mentioned ACell.

Awesome. So you went aggressive on me because you mixed up names of companies. And that's what happens when you refuse to provide any proof to your statements. And now go aggressive on me again for pointing out that nobody except you discussed ACell and both Hellouser and me were referring to RepliCel.

 

[Sparky4444]

...jeezus christ...I meant RepliCell, not ACELL...This is such a merry-go-round my head is spinning...

...yep folks...I think you all knew what I meant....well, some of you...

 

[benjt]

..based on that graphic, ACELL will be more viable before these guys...OMG, this is nuts...wtf is going on??

As your statement then apparently refers to RepliCel: Yes, that's what I was saying right from the start.

But, according to your expertise:

RepliCel for hairloss?? lmao! They're a joke... [...]
...if it smells like a rat, looks like a rat and sounds like a rat, it most likely is a rat...

So, what is it then. Is RepliCel now a rat, or a joke, or are they "more viable before [Follica]"? What's it gonna be from your side?

 

[Sparky4444]

..ummmm...where is anything being said about Phase 2 results??

http://www.replicel.com/replicel-to...e-japanese-society-for-regenerative-medicine/

What is up here?? They did Phase I/IIa -- that was completed back in 2012..then they were proceeding with Phase IIb...they just abandoned Phase IIb in North America and jumped to Japan and Sheisido..

bent -- better get online and invest on this baby...she sounds like a winner

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..my original post was "RepliCell for hairloss?? That's a joke.." ...and it is a joke...Phase I/IIa...advertised for IIb but now oral presenting on Phase I in Japan...another 3 year study?? 3 years to try and get something that will work for market, because it ain't working now....for bent, that's for sure...for the rest of you, that's just my opinion

 

[benjt]

RepliCel combined Phase I and IIa - which you would know if you had read their intermediate report.

The results they are going to present are interesting, as the previous results - which were impressive enough, with 12% after 6 months - don't show whether these gains actually stay (as the data to be presented are several months post-treatment) or if actually more growth is triggered. I wouldnt make any statements about whether they are "viable" or "a joke" or "nothing to be discussed" or "rats", nor about whether you should invest in them before we haven't seen the final phase 1/2a results which they now present.

because it ain't working now....

Aha. if you say so, then 12% increase in hair density over 6 months of course means "it ain't working now".

 

[benjt]

I said Phase I/IIa was completed 2 years ago...WTF are you talking about presenting findings on I/IIa?? Really?? Two years after the fact??

Again you have no clue what you are talking about. It is common practice to collect long-term post-treatment data for clinical trials. Almost every trial does this. The reason is to assess a) whether treatments provide long-term effects or if they vanish within x months after the treatment has been discontinued and b) long-term adverse effects. I'll just give a few examples for this:

"Clinical and bacteriological assessments were done monthly during treatment and for 24 months post-treatment." Source
"The bone densitometry will be done at baseline and following 24 months of letrozole or exemestane therapy." Source
"A longer-term analysis will occur at 24 months post load." Source

I think these three examples should suffice to show that it is common to do assessments 24 months post treatment.

The crap doesn't work...2 years LATER they're presenting findings PLUS they abandoned their IIb clinical studies...

Yes, it is completely normal to present 2 years later, as this is commonly done in almost every clinical trial (s. examples above for other clinical trials). And they did not abandon their phase IIb trials, they are commencing in Europe now.

But great that you found out that they're a joke because they do what every other company also does for trials. And great that you still ignore the 12% hair density increase after 6 months, which clearly shows that it does work. The question answered by the final results is whether these 12% stay or not.

...to all...bend-over is on my ignore list....

have at it bent-butt...done with you...

Of course. Because now you showed that you have no clue about clinical trials although you made statements earlier about how it is a joke to present two years after the trials end which almost every trial does (making almost every medical company a joke in your opinion, right?). The great thing, though, is that I will no longer be insulted.

 

[Breaking Bald]

They did not abandon their phase IIb trials, they are commencing in Europe now.

Are they? I couldn't find that info on their site, where is it?

 

[benjt]

It was in one of their report PDFs. One of the test sites was the Charite University Hospital Berlin which also serves as the coordinating site.

 

[Breaking Bald]

It was in one of their report PDFs. One of the test sites was the Charite University Hospital Berlin which also serves as the coordinating site.

Well that's good news I guess! What the **** happened to Histogen though? They've gone awfully quiet!!

 

[LayZ]

even if they grow these little puppies in a dish they still have to be planted into your head. You will still need a surgeon to do this, no?
I get the entire "unlimited supply" of hairs and all but really you can still get a botched job, semi high failure rate etc. I personally wait for the day a nice topical comes out that has ZERO sides except growing you back to much hair on your head.

Way more than cloning going on here. I believe Dr Cos called this the biggest breakthrough of 2013.

Researchers are no longer going to be restricted to mice, rats and crappy 2D in vitro cultures for determing the efficacy of a potential treatment. They can start the process of experimentation on 3D structures using real human cell cultures that respond much more accurately than anything other than actual human being.

Gene therapies, drug therapies... Add your own ideas here...

 

[I.D WALKER]

No recent update from their summit function last month either? I predict they will resurface in the next 3 weeks at best, during the calm of this feasable revolutionary break through.

Well that's good news I guess! What the **** happened to Histogen though? They've gone awfully quiet!!

 

[abcdefg]

Given the history of male pattern baldness maybe we should wait until we see everything working the whole process start to finish maybe replicated by someone else before we proclaim male pattern baldness is history.

 

[DesperateOne]

Given the history of male pattern baldness maybe we should wait until we see everything working the whole process start to finish maybe replicated by someone else before we proclaim male pattern baldness is history.

I agree, but the major stuff is solved. Now is just time to iron the kinks.

I have to agree with a poster a while back, the butchers will probably be the ones doing the operations. I guess they are not going to shake on their boots just yet.

 

[Sparky4444]

I agree, but the major stuff is solved. Now is just time to iron the kinks.

I have to agree with a poster a while back, the butchers will probably be the ones doing the operations. I guess they are not going to shake on their boots just yet.

The major stuff is solved??? If you think anyone has their foot on the neck of male pattern baldness, then you're surely just engaging in a mind-game to help you cope with it...

...2015 was the magic year everyone has been talking about for the last 5 years...it has always been "2015, 2015,2015"....as of right now, there is NOTHING for 2015 except for PiloFocus, and I'm not even getting excited about that because there have been a couple set-backs there in terms of delivery projections...

...If you're getting excited about RepliCell, then you can afford 5 years of waiting...most of us don't have 5 years to waste...and the fact they're crawling around the globe begging for places to further their research just doesn't give me any confidence that this thing even works...period...and when I mean "works", I mean grow the hair, it stays and you have a cosmetic difference -- anything less than 60% regrowth will not be good enough for most...

 

[Admin]

admin-public letter.

hi.
i understand your worry about the dangers out of dermarollingalsdjkf;alkdjf;alksdfj;alwkj;awlkejf;alwkefj;alkefj;alkwefj;awlkefj;alwkefj;alwef
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thank you.
​

Why are you throwing this in the middle of another thread? So it can't be locked?

 

[hellouser]

The major stuff is solved??? If you think anyone has their foot on the neck of male pattern baldness, then you're surely just engaging in a mind-game to help you cope with it...

...2015 was the magic year everyone has been talking about for the last 5 years...it has always been "2015, 2015,2015"....as of right now, there is NOTHING for 2015 except for PiloFocus, and I'm not even getting excited about that because there have been a couple set-backs there in terms of delivery projections...

Incorrect.

2014 was the projected date for Aderans until it got shelved by the corporate pigs that ran ARI.

...If you're getting excited about RepliCell, then you can afford 5 years of waiting...most of us don't have 5 years to waste...and the fact they're crawling around the globe begging for places to further their research just doesn't give me any confidence that this thing even works...period...

RIDICULOUS!

Replicel wasn't begging, Histogen pretty much is though! And what's wrong with Shiseido giving Replicel nearly 30 million dollars to further fund the trials??

anything less than 60% regrowth will not be good enough for most...

Forget percentages. None of us should be complacent with 'oh, you'll have 20% more hair.' Thats bullsh*t. What happens if youre slick bald? What's 20% more from ZERO hairs? I'll be satisfied when they say 'We can give you as many follicles and terminal hairs as you want'.

Anything less than THAT is not good enough!