I wouldn't say spironolactone is completely useless, it has its place. I was taking 2mg estradiol, 200mg spironolactone and duta with no real hair benefits, my crown is still very thin. My hair is very important to me but i would like to keep it without being on a regimen that is too extreme tbh. On all those other meds my orgasms were pretty much non existant, still not recovered. If i can keep my hair and sexual health at the same time i would be happy. My hair is ultimately more important than orgasms though.
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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I wouldn't say spironolactone is completely useless, it has its place. I was taking 2mg estradiol, 200mg spironolactone and duta with no real hair benefits, my crown is still very thin. My hair is very important to me but i would like to keep it without being on a regimen that is too extreme tbh. On all those other meds my orgasms were pretty much non existant, still not recovered. If i can keep my hair and sexual health at the same time i would be happy. My hair is ultimately more important than orgasms though.
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I tend to agree. My point is that, generally speaking, spironolactone is probably just a maintenance drug at best for most people. Individuals who are maintaining on finasteride+min shouldn't expect much from adding spironolactone. The most useful drug for a cis male (or anyone really) IMO is oral minoxidil, and is one of the few things that will almost always provide at least some degree of regrowth when added to a regimen. As far as a topical antiandrogen, there are several options. But RU or topical bica seem to be the most powerful to use topically, and it would seem that their systemic absorption is not very significant. From what I understand, spironolactone, on the other hand, is almost useless topically and should be used orally. I don't know what the reason is that people say that, but I wouldn't doubt it as we have lacked anecdotal evidence from topical spironolactone.
I was thinking of trying ketoconazole before RU, i only apply minoxidil once at night, so twice a day RU application is not something i would like to try just yet unless it is far more effective.
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Either is worth trying. In any case, they will likely just reinforce maintenance. Are you planning for a transplant in the future?
I have diffuse thinning crown that doesn't seem to respond well to treatments, there is also a spot i think may be scarring alopecia but im not sure, maybe it is just a difficult area to achieve regrowth.
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If the area is slick then you could safely needle it pretty aggressively. If it's not then I would needle more conservatively.
Im lightly needling with a 2.5mm roller before applying minoxidil, for just over a month now.
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where do you get your oral minoxidil?
How did you switched from CPA/spironolactone+E2 to Bicalutamide? Did you quit cold turkey? Then started bica after this?
Im wearing hair system to conceal my thin hairs but im still thinking about AA. Dutasteride/finasteride/Minoxidil doesnt work for me :/.
Were you still loosing hairs while taking cpa/e2 or just maintain?
on the advice of a trichologist, I was on minoxidil for a year, this year it only got worse. I tried finasteride, his hair began to fly strongly from him. then I tried a bika from him, too, there was a hair fall. only cpa helped me stop the fallout. I regret that I did not get on this topic before, I wasted a lot of time.
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Too much CPA, 12.5mg is enough for almost everyone too little Estrofem. finasteride sometimes comes with an initial shed, so as any hormone fluctuations. Be aware of your prolactin levels!
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Hi Dani!
Why aren't you using the 1.25 mg oral minoxidil dosage? he's just as effective. And what side effects to expect from oral minoxidil. Will it be effective simply when combined with topical minoxidil? Happy new year
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Will be a positive effect of taking minoxidil mono tablets without AA?
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Sure, just not as much as if you treated the hormonal pathway in some way. Could try a topical anti androgen with it
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Thanks for the answer. No more blockers and AA, even topically. Libido is everything)
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Oral minoxidil is the most powerful non-hormonal treatment
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Will the 1.25 mg dose be effective if the tablet is divided?
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It’s effective, but I would go for a higher dose if possible.