Most likely yes. When I was taking 25 mg of bica EOD I had less hair on my body and even on my beard. Now that i stopped it for a month already, I am getting hairy again.
There is a study that shows it.
https://www.jaad.org/article/S0190-9622(21)02738-9/fulltext
''All patients commenced bicalutamide at a dose of 10 mg. The mean dose of bicalutamide that reduced hypertrichosis was 14.4 mg (SD, 5.25 mg). The use of concurrent bicalutamide permitted an increase in the mean daily dose of minoxidil to 2.2 mg (SD, 1.67 mg) without development of hypertrichosis.''
''Oral bicalutamide appears to be beneficial in mitigating hypertrichosis caused by minoxidil in FPHL patients. Daily bicalutamide (mean dose, 14.4 mg) both reduced hypertrichosis and permitted an increase in the mean dosing of minoxidil by 0.7 mg/day without further hypertrichosis.''
As you can see per studies 14.4 mg is enough to reduce the hypertrichosis, so 25 mg EOD would be 100 mg a week and 14.4 mg ED is 100.8 mg a week so as you cant really take 14.4 mg the best bet is to use 25 mg EOD, which due to bica's half life it will be very similar than taking 14.4 mg ED.