Exploring The Hormonal Route. Hair=life.

[Adri23]

25mg bica on top of proper e2 injections makes ur skin good but gives you michael jackson face almost and thins hair out. i wonder if @Adri23 problem comes from him taking 25mg every other day as opposed to 12.5 daily. the 25mg dosage all at once may be hard on the liver or inherently start ar upreg somehow

Exactly. It made my dht to spike as well. I stopped it entirely. I havent taken it for an entire month and things got worse but I think my receptors must be hypersensitized after a year and 6 months on it.

25 mg daily with castrate levels of T is just poison

 

[Adri23]

I've been warning this for a long time and ppl thought I was crazy but it happens to more ppl

 

[exwhyyou]

i mean poison is going a bit far, i think you had a particularly bad reaction. since ive done this experiment twice now, i can say 25mg bica reacted exactly the same both times, with mogger skin and the hairline/partline gains getting fukkd. i expect the hair to improve within a few weeks on 12.5, just as it did last time, as well as more temperamental skin but whatever.

 

[sg2000]

2nd day pf taking 200 mg spiroo so excited

 

[sg2000]

I've been warning this for a long time and ppl thought I was crazy but it happens to more ppl

so im not gonna touch bica

 

[exwhyyou]

2nd day pf taking 200 mg spiroo so excited

how much water u drank today so far lil cuh

 

[Adri23]

so im not gonna touch bica

In my personal opinion (not everyone has to agree with me) I think one of the best treatment for Androgenetic Alopecia is estradiol injections, dutasteride at 2.5 mg or more and minoxidil. dutasteride at high dosage already inhibits like 80-90% 5ar1 and 98-99% 5ar2 so you would be left with castrate levels of T which shouldn't be a big issue.

 

[Adri23]

In my personal opinion, my skin was getting oilier when I stopped bica and was on daily 0,5 mg dutasteride, but after 3-4 weeks on high dosage dutasteride my skin started to fix. I did a blood test after and my DHT was 3.5 ng/dl.

 

[Adri23]

Low-mid doses spironolactone might also work for body hair since many women that has hirsutim uses it, but I can't say for sure since I've never tried it. All I know is bica is the only thing that worked for my body hypertrichosis from minoxidil, but the issues that can rise on the receptor with long term exposure is not worth it for me.


EDIT: There is a study on spironolactone and oral minoxidil hypertrichosis: https://pubmed.ncbi.nlm.nih.gov/39133327/#:~:text=Low dose oral minoxidil (LDOM,may reduce LDOM-induced hypertrichosis.

 

[4141241241241]

2nd day pf taking 200 mg spiroo so excited

so proud of u sis

 

[Almas_NW0]

I have not noticed any effect of Bicalutamide on my hair. But it does a great job of reducing oiliness of the skin, which greatly affects the quality of life (constant oil on the face is irritating), reduces pores and improves the quality of the skin in general.
I am skeptical that it can thin your hair because thinning means you are going bald again.
I take 37.5mg 3 times a week.

 

[sg2000]

I have not noticed any effect of Bicalutamide on my hair. But it does a great job of reducing oiliness of the skin, which greatly affects the quality of life (constant oil on the face is irritating), reduces pores and improves the quality of the skin in general.
I am skeptical that it can thin your hair because thinning means you are going bald again.
I take 37.5mg 3 times a week.

maybe a shed?But he said he lasted more than 6 months(?)

 

[Almas_NW0]

maybe a shed?But he said he lasted more than 6 months(?)

There was no shed. I only experienced shed once: when I switched to testosterone for 3 weeks and then switched back to E. Shed lasted 4 months and manifested itself in me seeing more hair in the shower than usual. I take Bicalutamide because without it my skin gets oily.

 

[sg2000]

i

There was no shed. I only experienced shed once: when I switched to testosterone for 3 weeks and then switched back to E. Shed lasted 4 months and manifested itself in me seeing more hair in the shower than usual. I take Bicalutamide because without it my skin gets oily.

i was talking about adri.He might have a shed when upped bica

 

[sg2000]

i just want to find an explanation for adri being below baseline after upping the bicalutamide dose,its not f*****g possible

 

[BRezende]

i just want to find an explanation for adri being below baseline after upping the bicalutamide dose,its not f*****g possible

The explanation is that your cell can produce any androgen in its nucleus using cholesterol as fuel.

 

[sg2000]

The explanation is that your cell can produce any androgen in its nucleus using cholesterol as fuel.

so low cholesterpl diet should help?

 

[Adri23]

so low cholesterpl diet should help?

No lol. Your liver makes all the cholesterol your body needs, even with a low cholesterol diet

 

[Adri23]

Only way to stop this curse is a PROTAC. I really hope gt20029 end up working as in theory

 

[exwhyyou]

having a particularly great hair day today a few days back into 12.5mg bica. skin and hair less dry already. i imagine an ache breakout is on its way but i'm happy i ended my 25mg experiment as of right now.