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Literally p**rn.
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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Premature androgenetic alopecia has been suggested as a sign of the male equivalent of polycystic ovary syndrome. However, the hormonal background of men with premature baldness has been studied in only a few studies with conflicting results. We examined 37 men with premature alopecia (defined as frontal-parietal and parietal alopecia under the age of 30 years with alopecia defined as grade 3 or more apical alopecia on the Hamilton alopecia classification scale with the Norwood modification). Plasma concentrations of total testosterone, dihydrotestosterone, epitestosterone, androstenedione, cortisol, 17-OH-progesterone (17OHP), estradiol, LH, FSH, prolactin, SHBG and TSH, and free thyroxine were measured. The frequency of subnormal values of SHBG, FSH, testosterone, and epitestosterone (but not in the free androgen index) was significant in balding men. A borderline significant trend was observed for elevated levels of 17OH-P and prolactin. The hormonal background of a significant number of men with premature baldness in some respects resembles the hormonal background of women with polycystic ovary syndrome.
I'm talking about stopping baldness, not regrowing. Castration or taking doses of Bicalutamide equivalent to it should at least stop the progression, but people continue to go bald further
Removal of androgens should stop further follicular miniaturization. Often, when castration or taking Bicalutamide, this happens, but not in all people. On this forum, a man who castrated himself stopped baldness and reversed miniaturization.
Yes, 50mg is weaker than castration, but 75-100mg is equivalent to it, and 150mg is superior
Yes, I was talking about him. Castration stopped his baldness. Stopping baldness is already a victory
Bicalutamide in high doses reduces PSA by 93% +, as does castration. Survival for prostate cancer is higher with Bicalutamide 150mg than with castration. And given the increase in E, this is all the better for hair.
Because after 3 months he got a slight regrowth. An obvious sign of stopping the progression of baldness
I did not say that Bicalutamide and castration are the same thing. I said that they are equivalent in efficiency. Yes, they have a fundamentally different mechanism of action.
A sign of a successful blockade of androgens in the scalp and stopping the destructive action of androgens on the follicles is an increase in the diameter of the hair, i.e., reversing miniaturization. This is not possible if androgens continue to destroy the follicle.
The study deals with very damaged or bald areas. Yes, in such cases, neither castration nor Bicalutamide will help, even high doses of E may not save the situation
Partly because of the deterioration in blood flow, it is impossible to completely restore the temples, even on HRT. This again prompts us to start treatment before irreversible fibrosis occurs. The crown is less susceptible to these changes, so it responds better to any treatment
If you want to stop baldness, you have nothing better. The chances are high. If you want to achieve perfect hair, or you have bald areas / areas with heavy thinning - yes, only HRT will help you
This does not help everyone, as can be seen from the participants in this forum. However, we have people with aggressive baldness who have not only gotten a stop, but also good hair growth. DHTcel, Maave, Ein. Bicalutamide is the best we have. I do not guarantee anything and I just hope that I will be one of the lucky ones.
The next level is HRT. I would not want to resort to it, especially forever. Moreover, for those who did not respond to Bicalutamide, HRT also has a lower effectiveness - there are people who are not susceptible to any treatments.
May I know your regime?
Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia
Androgenic alopecia (Androgenetic Alopecia), also known as male pattern baldness, is one of the most common hair loss diseases worldwide. The main treatments of Androgenetic Alopecia inc…
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To be honest, I'm getting worse. If it doesn't stop, I'll switch to 100mg Bicalutamide, then 150mg, and then HRT. If HRT does not help me, or I feel dysphoria due to feminization, before committing suicide, I will say goodbye to the participants in this forum.
if you are genuinely feeling that way you really need to talk to someone because that's not a normal reaction. Good luck to you.
Hair plays a big role in our life and human beauty, losing it is a really serious problem. In my life I have seen a lot of sh*t, I suffered from various diseases, some of them could make me disabled, but there was nothing worse than baldness
I feel for you I really do, but just remember we're all here to help each other, yes hair loss is a problem but it's just hair you have to step back in get the perspective.
All the best to you.
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I think many people have tiny hairs there including me but that’s as far as it goes. Most successful was antydhtor but you know what he was on and I think he was in his 20’s so age makes a difference