Finasteride cause DNA damage . new study in vivo

JohnSmith21

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It's everyones own lifes at the end of the day. I would, however, encourage everyone to thoroughly think twice of getting kids while being or having been on finasteride for extended periods of time. You will have to live with the outcome for the rest of your life, and so does the kid.
I’m gonna stop taking it for a few months when I have kids just in case
 

JohnSmith21

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it’s wild to me thought that pigeon can suggest like 4 things that most likely will do nothing for your hair (like zix) and then topical duesteride, which for all we know has more sides as .5mg of oral finasteride per day lmao.
 

czecha

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I’m gonna stop taking it for a few months when I have kids just in case
Better than nothing I guess, but you'll never know if there are still implications. I wouldn't be able to live with that. Imagine sitting at lunch with your ugly son, and you'll never know if it was the finasteride. My life would be ruined.
At least get sperm DFI and semen parameters measured before if your mind is set anyways, but that's just my opinion. There is a study on sperm dna damage out there somewhere.
 

JohnSmith21

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Better than nothing I guess, but you'll never know if there are still implications. I wouldn't be able to live with that. Imagine sitting at lunch with your ugly son, and you'll never know if it was the finasteride. My life would be ruined.
At least get sperm DFI and semen parameters measured before if your mind is set anyways, but that's just my opinion. There is a study on sperm dna damage out there somewhere.
I mean it’s totally out of your system in a month, so I would wait a month, get a sperm test, and then start trying lol
 

czecha

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I mean it’s totally out of your system in a month, so I would wait a month, get a sperm test, and then start trying lol
DNA damage might already be done. We don't know if it's reversible and how long that would take. This thread is about DNA damage otherwise I wouldn't have brought this up.
You are not guaranteed to provide healthy dna for your child after a month off finasteride. You can talk yourself into it if you'd like, or just take the risk and live with it. For me, it's irrelevant if that risk is 90% or 5% since I wouldn't be able to live with it either way. If I'm getting sons like rob lowe I am sure as f*** going to want to know that it's not my fault.
 

JohnSmith21

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DNA damage might already be done. We don't know if it's reversible and how long that would take. This thread is about DNA damage otherwise I wouldn't have brought this up.
You are not guaranteed to provide healthy dna for your child after a month off finasteride. You can talk yourself into it if you'd like, or just take the risk and live with it. For me, it's irrelevant if that risk is 90% or 5% since I wouldn't be able to live with it either way. If I'm getting sons like rob lowe I am sure as f*** going to want to know that it's not my fault.
Dude.... there is zero proof of this too. This forum is wayyyyy to crazy for me sometimes to be honest. Like what do you just think of something random and link it to finasteride? There’s no evidence of this and I don’t even think this is anything of concern. Your cellphone you keep in your pocket probably has a higher chance of making your future kid ugly
 

JohnSmith21

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This proves again you know nothing. (no wonder you believe fina is safe)

Do you even know about how many people have success with minoxidil/needling combo? Check out the big thread.

About topical duta, there is a theory why it causes les sides and a couple of users here confirm that theory, they had sides on oral fina and even topical fina but not on topical duta. ( https://fuehairdoctor.co.uk/topical-dutasteride-dr-lupanzula/ )

If you still take oral fina/duta anno 2020 you really know nothing or don't care about your health imo.
Ohhhhh okay cool dude a theory that it causes less sides by a couple of crazy people on the internet, that’s for sure more legit then the hundreds of studies and proven safety profile of finasteride over the last 30 years
 

Catagen

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DNA damage might already be done. We don't know if it's reversible and how long that would take. This thread is about DNA damage otherwise I wouldn't have brought this up.
You are not guaranteed to provide healthy dna for your child after a month off finasteride. You can talk yourself into it if you'd like, or just take the risk and live with it. For me, it's irrelevant if that risk is 90% or 5% since I wouldn't be able to live with it either way. If I'm getting sons like rob lowe I am sure as f*** going to want to know that it's not my fault.
Rob Lowe's sons were born before he started taking finasteride. Rob Lowe started finasteride in 98' and his sons were born in 95' and 93'. You only have their cases to back your claim up. Not saying dna damage is reversible btw just saying Rob Lowe's case doesn't apply here.
 

JohnSmith21

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This proves again you know nothing. (no wonder you believe fina is safe)

Do you even know about how many people have success with minoxidil/needling combo? Check out the big thread.

About topical duta, there is a theory why it causes les sides and a couple of users here confirm that theory, they had sides on oral fina and even topical fina but not on topical duta. ( https://fuehairdoctor.co.uk/topical-dutasteride-dr-lupanzula/ )

If you still take oral fina/duta anno 2020 you really know nothing or don't care about your health imo.
That’s great man but topical Duta still has no long term studies so what your saying is hyperbole and hypocritical. For all you know topical duta can mess you up down the line. Idgaf about a theory lmao I care about the proven safety profile since the 90s tho
 

JohnSmith21

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Rob Lowe's sons were born before he started taking finasteride. Rob Lowe started finasteride in 98' and his sons were born in 95' and 93'. You only have their cases to back your claim up. Not saying dna damage is reversible btw just saying Rob Lowe's case doesn't apply here.
I really don’t understand how you don’t feel blatantly insane proving your point with the sentence “rob lows kids....” like your on to something
 

czecha

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Rob Lowe's sons were born before he started taking finasteride. Rob Lowe started finasteride in 98' and his sons were born in 95' and 93'. You only have their cases to back your claim up. Not saying dna damage is reversible btw just saying Rob Lowe's case doesn't apply here.
Fair enough
Also not saying it does cause DNA damage, just saying idk if it does and that I doubt any1 has a full enough picture of everything to rule it out. Which is enough for me to make a decision
So just sharing my though process
 

czecha

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I really don’t understand how you don’t feel blatantly insane proving your point with the sentence “rob lows kids....” like your on to something
A bad anecdote then yes, but the point still stands
 

JohnSmith21

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Fair enough
Also not saying it does cause DNA damage, just saying idk if it does and that I doubt any1 has a full enough picture of everything to rule it out. Which is enough for me to make a decision
So just sharing my though process
Do you realize how many things cause DNA damage? The pesticides on your food cause DNA damage, and I doubt you need to respond like a crazy person. My point is cherry picking one thing to justify something is pointless, and you can do it with anything
 

JohnSmith21

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Do you realize how many things cause DNA damage? The pesticides on your food cause DNA damage, and I doubt you need to respond like a crazy person. My point is cherry picking one thing to justify something is pointless, and you can do it with anything
Like I bet if you were born and raised in the wilderness away from pesticides, gmos, and technology, you’d be healthier and have healthier kids. Can I prove this? No lol. Should you do this? Absolutely not. You get why your points are silly now?
 

Geezer

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This was a well written response. I guess what I meant by sides is noticeable sides. Advil has sided, an egg I eat has sides. Everything has sides, I get that your taking that route. I meant most people will not notice anything negative that they can attribute to finasteride, and if they do, it will most likely go away when they stop taking it. You’ve been on for 16 years, what has your experience been?
As stated in my post, I have been great. I may not be a great example as I do fall into the minority of men in North America with great health. Which is one of the things that pisses me off about these forums. It cannot be that these sub population of men who are on hair loss forum or subreddit seems to all be below 15% body fat, do weekly strenuous exercise, eat a micronutrient dense diet, and take care of vitamin deficiency as well as compensate for finasteride effects on the body.

40% of American are OBESE with the number of men overweight, being extremely height in adult hood

20% of the population get the “recommend” amount of exercise.

Sever vitamin deficiency and poor diet are also a play a huge play in health

it cannot be that every man of these forums are these epitome of health. Now I am not saying that doing the things I state above will GUARANTEE you do not have severe side effects, however any intelligent person will definitely agree it minimizes it. Bad health is typically a a combination of multiple things going wrong not just one. Cognition and well-being is multivariable not specific things, majority of the time.


A important thing to mention though, your interpretation on my finasteride post is incorrect. This comparison of “eggs” to finasteride is getting into a territory of use thinking like computers, everything it 1’s and 0’s. Maybe my post seems to positive but, finasteride as stated is not somthing to be taken lightly, and if society did not view baldness so negatively I actually would see no point unless in using finasteride unless for enlarged prostate.

Now that does not mean I think finasteride is poison, like almost everything in life it’s a pros to cons on a personal level, based on the research given. My main concern 18 years ago, when I started considering finasteride was cognition, being there was very little research on that area and Finasteride in general. I would say me staying on the drug is a testament to how big of an effect it has, which is minimal especially with compensating in other areas. The issues with liver, diabetes, insulin resistance and etc never bothered me due to my extreme diligence in maintaining good health and at minimum 2 blood tests a year, covered by insurance of coarse.

Anyways, I would say that is something I agree with Pigeon, that exact statement of “Eggs gives you sides” is completely downplaying what finasteride is. Again in a perfect world we would not inhibit 5AR and be able to keep our hair but, unfortunately not the case. You young guys though in 2020 are extremely lucky with the information you have at hand. So funny watching More plates more dates as he has to me the most middle ground view point on it, basically emphasizing it’s only optimal for hair and prostate. Although I think he also understands his lifestyle helps drastically minimize the effects of inhibiting 5AR, along with actually being knowledgeable on the topic unlike 99% of people who post on forums.
 

czecha

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Do you realize how many things cause DNA damage? The pesticides on your food cause DNA damage, and I doubt you need to respond like a crazy person. My point is cherry picking one thing to justify something is pointless, and you can do it with anything
Finasteride is a nuke. Pesticides, which I am obviously trying my best to acvoid (I literally am mostly making money to spend it on high quality food) are at best a problem that accumulates. Your comparison is bogus. As if finasteride Was just another environmental stressor, jfl
 

Geezer

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Like I bet if you were born and raised in the wilderness away from pesticides, gmos, and technology, you’d be healthier and have healthier kids. Can I prove this? No lol. Should you do this? Absolutely not. You get why your points are silly now?
Correct on this point, multiple environmental factors both positive and negative can change your DNA.
 

JohnSmith21

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Finasteride is a nuke. Pesticides, which I am obviously trying my best to acvoid (I literally am mostly making money to spend it on high quality food) are at best a problem that accumulates. Your comparison is bogus. As if finasteride Was just another environmental stressor, jfl
How is finasteride a Nuke lmfao? Lowering dht by 70% is a nuke??? Thats your opinion, as the science does not back up finasteride being a “nuke” even slightly. I’m on finasteride. I bench almost twice my weight, my sex drive is good, I grow a beard, and my hair is better! You all talk in hyperboles it’s actually insane.
 

Geezer

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Better than nothing I guess, but you'll never know if there are still implications. I wouldn't be able to live with that. Imagine sitting at lunch with your ugly son, and you'll never know if it was the finasteride. My life would be ruined.
At least get sperm DFI and semen parameters measured before if your mind is set anyways, but that's just my opinion. There is a study on sperm dna damage out there somewhere.
Correct while on the drug, discontinuation demonstrated everything going back to baseline. Few people have extreme reaction and can impact it more harshly. But correct in a pros and cons way of thinking, you should definitely discontinue finasteride before trying to conceive a child.
 

czecha

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How is finasteride a Nuke lmfao? Lowering dht by 70% is a nuke??? Thats your opinion, as the science does not back up finasteride being a “nuke” even slightly. I’m on finasteride. I bench almost twice my weight, my sex drive is good, I grow a beard, and my hair is better! You all talk in hyperboles it’s actually insane.
yes, you nuked one of the hormones that make you think, act, look and feel like a male by 70%. which is why it's prescribed to trannies
If it works out for you, that's great. If you think it will work out for your kid, that's also great. Heck, it might!
 
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