Nothing seems to work, growing more frustrated and feeling lost

[ZLulic]

So far I have tried all the approved methods: minoxidil + nizoral for over 6 months, minoxidil + microneedling 6 months, minoxidil + finasteride for over a year. Nothing helps with regrowth on the front. A month ago I started minoxidil + tretinoin 0.025 % for better enzyme activity (it is supposed to turn non responders in responders). So far nothing changed besides having dry and flaky scalp from the tretinoin cream. I know that people usually wait 3-4 months to see results but it seems like adding tretinoin doesn't even make a slight difference in terms of vellus hair appearing. I never got to the point where I would see signs of improvement and be like "finally, this treatment works, I can keep going with it".

I am afraid I am wasting another 6 months but I also don't want to try the kitchen sink method by taking several treatments all at once. As times goes by I am becoming more frustrated and restless. I can't really concentrate on anything and feel anxious. At first I didn't feel like this because I felt optimistic that the treatments would work (back in 2019), now I am mentally worse than ever before. I running out of options.

 

[Mr. Slap Head]

Oral minoxidil + topical antiandrogen

 

[ZLulic]

Oral minoxidil + topical antiandrogen

I have already low blood pressure naturally, wouldn't oral min. make it even worse? Topical antiandrogen: as in topical finasteride or RU or both?

 

[losingbattle88]

I have already low blood pressure naturally, wouldn't oral min. make it even worse? Topical antiandrogen: as in topical finasteride or RU or both?

I feel u. If my regiment fails me in the Long run im out of options. Already tried RU years ago. May use spironolactone even if its weak but daily application Will get expensive in the Long run and im just not up for it. Already spend alot of money on My damn hair as it is

 

[Mr. Slap Head]

Topical bica is another option and only needs applied once a week

 

[losingbattle88]

Topical bica is another option and only needs applied once a week

Where can i get it in Europe without stupid customs seize it? My country is super strict they stop supplements even.

 

[Adri23]

Topical bica is another option and only needs applied once a week

But it can go systemic right?

 

[Mr. Slap Head]

Where can i get it in Europe without stupid customs seize it? My country is super strict they stop supplements even.

I’m not sure. Maybe someone on the hormonal thread knows. My country has it available so I do not know, I’m sorry. I get it off Alldaychemist.

But it can go systemic right?

everything goes systemic to a degree. Bica has a fairly large molecular weight and poor solubility so really it would be difficult to have problems with it once or twice a week.

 

[Adri23]

everything goes systemic to a degree. Bica has a fairly large molecular weight and poor solubility so really it would be difficult to have problems with it once or twice a week.

Doesn't it feminize if u use it once a week then?

 

[losingbattle88]

I’m not sure. Maybe someone on the hormonal thread knows. My country has it available so I do not know, I’m sorry. I get it off Alldaychemist.




everything goes systemic to a degree. Bica has a fairly large molecular weight and poor solubility so really it would be difficult to have problems with it once or twice a week.

Ye alldaychemist ship from india i believe customs took My pack of spironolactone pills from india once its a gamble for me. The chance of getting it is Slim. Is bica pills? How expensive is it and what does it do in the Body?

 

[Mr. Slap Head]

Doesn't it feminize if u use it once a week then?

Not topically

Ye alldaychemist ship from india i believe customs took My pack of spironolactone pills from india once its a gamble for me. The chance of getting it is Slim. Is bica pills? How expensive is it and what does it do in the Body?

Yeah they are 50mg pills. You only need a 1% concentration so it can go a pretty long way. 1-2mL is 10-20mg once or twice per week, by contrast, HRT people typically use it at 50-75mg DAILY and orally which can cause gyno. It is an antiandrogen which can outnumber androgens, thereby preventing them from binding to the receptor. So using it topically, the idea is to target that mechanism in the scalp tissues.

 

[Adri23]

Not topically


Yeah they are 50mg pills. You only need a 1% concentration so it can go a pretty long way. 1-2mL is 10-20mg once or twice per week, by contrast, HRT people typically use it at 50-75mg DAILY and orally which can cause gyno. It is an antiandrogen which can outnumber androgens, thereby preventing them from binding to the receptor. So using it topically, the idea is to target that mechanism in the scalp tissues.

How do you make it? I'm really interested about this and I think I can get the 50mg pills easy, so I only need to know how to do it because i'm really awkward at doing these stuff.

 

[Mr. Slap Head]

How do you make it? I'm really interested about this and I think I can get the 50mg pills easy, so I only need to know how to do it because i'm really awkward at doing these stuff.

Just mixed a fresh batch. Takes a few minutes. Very simple, you only need to put it in pure ethanol. So one 50mg pill will be 5mL of alcohol which could last you a week. You could do 2x50mg pills and mix it in 10mL of alcohol to last a while longer, and so forth. I lightly needle before application to ensure absorption (no bleeding, just get the skin pink).

 

[Adri23]

Just mixed a fresh batch. Takes a few minutes. Very simple, you only need to put it in pure ethanol. So one 50mg pill will be 5mL of alcohol which could last you a week. You could do 2x50mg pills and mix it in 10mL of alcohol to last a while longer, and so forth. I lightly needle before application to ensure absorption (no bleeding, just get the skin pink).

I don't do really good with ethanol, is there another alternative?

 

[20YearsOnFin]

So using it topically, the idea is to target that mechanism in the scalp tissues.

Have you noticed any regrowth using it then? or have you only recently started using it?

 

[Mr. Slap Head]

I don't do really good with ethanol, is there another alternative?

I am not sure. Try asking Experimentality.

 

[Mr. Slap Head]

Have you noticed any regrowth using it then? or have you only recently started using it?

Only been using it about 2 months but there are good signs so far. It's been a good replacement for RU which is expensive and inconvenient.

 

[Adri23]

Just mixed a fresh batch. Takes a few minutes. Very simple, you only need to put it in pure ethanol. So one 50mg pill will be 5mL of alcohol which could last you a week. You could do 2x50mg pills and mix it in 10mL of alcohol to last a while longer, and so forth. I lightly needle before application to ensure absorption (no bleeding, just get the skin pink).

Do you use 1mL or 2mL per week?

 

[Mr. Slap Head]

Do you use 1mL or 2mL per week?

about 2mL every 4-5 days or so

 

[Adri23]

about 2mL every 4-5 days or so

Do you maintain only with that or are you using finasteride/dutasteride/min? I'm on dutasteride and minoxidil and I'm still losing ground slowly so i think if i stack those 3 it will work.