Published in Nature: Weekly treatment with SAMiRNA targeting the androgen receptor ameliorates androgenetic alopecia

[Nehel]

CosmeRNA has a website now (empty unfortunately): https://www.cosmerna.co/

 

[purupa]

I really want to get my hands on this ASAP and stack it with finas/minoxidil . 7 hair/cm2 increase after 16 weeks its not bad at all, people say the big 3 of hair loss are minoxidil finas and nizoral , but if this actually works as the research paper says, this should replace nizoral

 

[ZLulic]

Nizoral? No this can replace fina if it actually works as they say.

IIRC it was 83% as effective as finasteride, so not entirely but pretty close.

 

[Ralph Wiggum]

But wait, the original article said: In the high-dose (5 mg/ml) clinical study, AR68 was given once per week for 24 weeks and showed 83% efficacy in increasing hair counts compared with finasteride.

 

[ZLulic]

But wait, the original article said: In the high-dose (5 mg/ml) clinical study, AR68 was given once per week for 24 weeks and showed 83% efficacy in increasing hair counts compared with finasteride.

This is what I was originally referring to.

 

[Super Metroid]

But wait, the original article said: In the high-dose (5 mg/ml) clinical study, AR68 was given once per week for 24 weeks and showed 83% efficacy in increasing hair counts compared with finasteride.

I think that is the 7.6 (Samirna regrowth after 4 months) / 9.3 (propecia regrowth after 6 months) which is about 0.83.

However, obviously, the per month gain was higher in Samirna than for propecia and it had a higher response rate. This indicates that it would be a superior product to finasteride (not that it matters, they work different pathways). But I am always suspicious of information. Is the stated efficacy and safety indeed true and how about the longer term? Do the results hold up after 6 / 12 months or does it collapse after that?

 

[RoryGall29]

Possible release date?

 

[Baldingtooyoung]

Possible release date?

5 years from now

 

[Nehel]

Possible release date?

H2 2022 apparently.

New Hair Growth Cosmeceutical Using siRNA With Published Study: CosmeRNA Review - Follicle Thought

Bioneer Targets H2 2022 Euro Launch Of CosmeRNA: Update (3/9/22) Bioneer/siRNAgen has apparently been evaluating its CosmeRNA product for cosmetic regulatory approval in Germany over the past several months. Various news outlets in the Korean press reported on March 8, 2022 that CosmeRNA has...

folliclethought.com

 

[purupa]

Nizoral? No this can replace fina if it actually works as they say. The big hope is that this will be without sides... but hey, we will only know if we'll try ourselves.

Sorry, I meant it as the big 3 would be finas/minoxidil/samirna , since samirna can be stacked with finas and produces great results. Of course, people who get sides from fina could replace it with this product. I think my point was addressing people who complain about this product when its shown superior efficiency to one of the big 3 (nizoral) and comparable efficiency to the other one (fina). IF (this is a big IF) it works as good as reported, I'd like to say this is almost a game changer

 

[poopfeast420]

5 years from now

It's supposed to be out as a cosmetic in EU this year. No reason we shouldn't be able to import it

 

[Super Metroid]

Yes IF it actually works and without sides this in an absolute game changer. But I don't want to get hyped before we get our hands on it.

And whether it remains effective after the dreaded 6/12 months mark.

 

[pegasus2]

Post | Brighter Side News

www.thebrighterside.news

Study reminds me of this

Such a misleading headline.

 

[whatevr]

Yes IF it actually works and without sides this in an absolute game changer. But I don't want to get hyped before we get our hands on it.

Oh I've already seen and heard of so many 'game changers' but the game is still the same, only the players change. Hahaha.

 

[-specter-]

Oh I've already seen and heard of so many 'game changers' but the game is still the same, only the players change. Hahaha.

it's time to clear the bank this time

 

[whymedamn]

so this year in the EU. That is huge. Where could we get it in that case? Over the counter?

Also, estimated costs? Apply just once in a while so that is great ..

 

[RoryGall29]

This + KX-826 can have the potential to completely freeze the hair loss progression without touching the hormonal profile...

 

[whymedamn]

so this will be here in EU in 2022. But when will KX-826 be here?

This + KX-826 can have the potential to completely freeze the hair loss progression without touching the hormonal profile...

 

[Dolph]

Looking back at the literature on this one, it's hard to deny that the photos from the study show almost no progress, even though the numbers seem good. I'm having trouble understanding this discrepancy.

 

[Dr sanches]

Looking back at the literature on this one, it's hard to deny that the photos from the study show almost no progress, even though the numbers seem good. I'm having trouble understanding this discrepancy.

It’s supposed to be a maintenance drug