MY EXPERIENCE:
Ive been on isotretinoin now for 7 months for adult acne and have not noticed any change in my hair besides vellus hairs along my temples. (front hairline + crown seem the same) This being said... I've been on 5% minoxidil and 1mg finasteride for 3 years now. (I'm 26, NW2 with slight vertex thinning)
I take 20mg a day and just became acne free (99%) about a week ago. (Plan on doing every other day after new years)
The only side effects I've noticed are chapped lips, sore lower back and slight depression / memory loss.
WARNING:
While I've noticed decreased memory and slight depression I can not be 100% certain it was due to the isotretinoin.
I'm not saying this stuff helps with hairloss nor do I support it's use for anything other than a "last resort" acne cure. But I thought I'd give my experience with this stuff and hopefully update this thread again if I notice any changes.
NOTE: If you plan on self-medicating, through my 'research' I've found Cipla to be the best generic that's easily obtainable. Though I've read that the potency is more like 10mg-15mg.
WILD CONJECTURE:
It's possible isotretinoin prevents some form of hyperkeratinization that's brought on by the effect of DHT on your hair follicles.
Ive been on isotretinoin now for 7 months for adult acne and have not noticed any change in my hair besides vellus hairs along my temples. (front hairline + crown seem the same) This being said... I've been on 5% minoxidil and 1mg finasteride for 3 years now. (I'm 26, NW2 with slight vertex thinning)
I take 20mg a day and just became acne free (99%) about a week ago. (Plan on doing every other day after new years)
The only side effects I've noticed are chapped lips, sore lower back and slight depression / memory loss.
WARNING:
Isotretinoin but not antibiotic treatment was associated with decreased brain metabolism in the orbitofrontal cortex (–21% change versus 2% change for antibiotic), a brain area known to mediate symptoms of depression. ( http://www.ncbi.nlm.nih.gov/pubmed/15863802 )
While I've noticed decreased memory and slight depression I can not be 100% certain it was due to the isotretinoin.
I'm not saying this stuff helps with hairloss nor do I support it's use for anything other than a "last resort" acne cure. But I thought I'd give my experience with this stuff and hopefully update this thread again if I notice any changes.
NOTE: If you plan on self-medicating, through my 'research' I've found Cipla to be the best generic that's easily obtainable. Though I've read that the potency is more like 10mg-15mg.
WILD CONJECTURE:
Acne is a disease of pilosebaceous units in the skin. It is thought to be caused by the interplay of four factors. Excessive sebum production secondary to sebaceous gland hyperplasia is the first abnormality to occur. Subsequent hyperkeratinization of the hair follicle prevents normal shedding of the follicular keratinocytes, which then obstruct the follicle and form an inapparent microcomedo. Lipids and cellular debris soon accumulate within the blocked follicle. This microenvironment encourages colonization of Propionibacterium acnes, which provokes an immune response through the production of numerous inflammatory mediators. Inflammation is further enhanced by follicular rupture and subsequent leakage of lipids, bacteria, and fatty acids into the dermis. ( http://www.aafp.org/afp/2004/0501/p2123.html )
It's possible isotretinoin prevents some form of hyperkeratinization that's brought on by the effect of DHT on your hair follicles.