Setipiprant Does Work, But Only On Really Really High Doses.

[icecold7]

Don't worry, I had an initial shed on seti in the beginning as well. After month and half it stopped.

That makes me feel a bit better (although 6 weeks of this and not sure I'll have any hair left!!)

@Pigeon , do you feel the seti has now stabilized your hair?

Anyone else get initial shedding with Seti?

 

[ZenHead]

I’ve been in contact with Kane about getting the acid form of seti which is better than the salt form for taking orally. He said he only sells the salt due to it being more soluble in ethanol for topical application. Is anyone else interested in the acid form for the oral route? I’m going to ask if he could possibly start making the acid form but I doubt he would do it unless we have more people interested in it.

 

[icecold7]

I’ve been in contact with Kane about getting the acid form of seti which is better than the salt form for taking orally. He said he only sells the salt due to it being more soluble in ethanol for topical application. Is anyone else interested in the acid form for the oral route? I’m going to ask if he could possibly start making the acid form but I doubt he would do it unless we have more people interested in it.

HA! I just asked him the same exact thing earlier today. If anyone else is interested in the acid version, ask Kane and hopefully he'll procure it.

On a related note, another member of this forum has a supplier in China and he gave me their contact info. This member said that he tested a product from this supplier (but not the seti) and it tested legit. Given that it's from China (and not Kane), I'm still not comfortable taking it without testing it first. So my plan is to order some from this person, get it tested, and then try it if it tests legit.

Today I asked the supplier about 1) shipping details, 2) acid vs. salt, and 3) purity. This is his response.

 

[icecold7]

So, kane's seti is legit? I'm about to order 100g of it, and take 500mg every 12 hours. Just need to know if it's the real deal, since apparently he only sells the salt version which is less effective from my understanding.

And yes, Kane's seti seems legit per @Sanchez1234's test (post #278 on this thread), but it's the salted version rather than the acid version. The acid version is the version that Kythera is testing orally. The molecule is different and it's unclear to me if than means the effects will be different. Janoshik seems to think there would be no difference (post #284), but given the money and time spent on a seti regimen, it seems to me that I don't want any other variables.

 

[CinnamonRoll]

Seems like the best bet is Fevi if money is a concern. Seems to be 1/5 the price per gram of Seti and requires 1/10 the dose
https://www.alibaba.com/product-det...tml?spm=a2700.7724838.2017115.1.275bfceOA9oTW

Study showing mast cell activation (in doves of all things) can be triggered by hormones like dht, t. Mast cells are the primary storage site for pgd2.

Two studies now published via University of Rome showing increased growth with topical cetirizine.

Mast cell activation is likely the most plausible explanation for the male pattern baldness itch.

Dht & t activate mast cells in the scalp (either directly or indirectly) > pgd2 is released as well as other "allergic" related inflammatory cytokines > itch occurs.

Itching is typically the result of "allergic" or mast cell mediated inflammation. Other types of inflammation do not typically create an itch. For example joint inflammation triggers an ache.

But our scalps don't ache. They itch. Which suggests a very logical role for antihistamines in safely reducing that type of inflammation.

 

[Jonnyyy]

Seems like the best bet is Fevi if money is a concern. Seems to be 1/5 the price per gram of Seti and requires 1/10 the dose
https://www.alibaba.com/product-det...tml?spm=a2700.7724838.2017115.1.275bfceOA9oTW


View attachment 74299

Why are people not on fevi already then?

 

[jamesbooker1975]

Seems like the best bet is Fevi if money is a concern. Seems to be 1/5 the price per gram of Seti and requires 1/10 the dose
https://www.alibaba.com/product-det...tml?spm=a2700.7724838.2017115.1.275bfceOA9oTW


View attachment 74299

Did you ask for the price ? I asked and was extremely expensive, far more than seti. They gave me 980 usd per gram ! ( the Shanghai Handim Chemical Alibaba seller )

 

[Sanchez1234]

Try LUO (the daro supplier). He dropped seti price under the kane seti price when i showed him the prices of Kane. He is legit and can produce a lot.

2hpharm.com

 

[Sanchez1234]

How you doing? Are you going on seti or not?

I cant take it... my heartbeat is times 4 and i can't sleep...

 

[Sanchez1234]

How you doing? Are you going on seti or not?

I upped my dose daro instead becaus

Didn't you also take fina and had a higher heartbeat?

What's your gameplan now?

With finasteride i had gyno. With minoxidil i had higher heartbeat as well.

My gameplan now i Daro. Just upped my dose. I had some side effects in the beginning but for now i seem to be side effect free.
Nonresultd so far

 

[proscar2]

Hi people. Can we please cleat up this seti issue with all the supposed different versions?

According to my sources there is the acid version, a sodium version(?) a salt version and according to one member a freebase.

can anyone (users/or not) clarify, simplify the above?)

The reason for this post is (to add to the confusion ) that chemical 'salts' are usually made in chemistry using various acids which would imply that the 'salted' version is the same as the acid version and people are just confusing chemical terminology?

this says nothing of course about the 'sodium' and the free-base' could we get this sorted out and clarified once and for all.

Finally do anyone have the precise chemical nomenclature for EACH version of seti to distinguish each and every form?

any help would be most appreciated!!!!!!!!!!!!!!!!!!!!!!!! merry xmas by the way- sorry to disturb your Xmas people and have a great new year.
I for one will do if i can get an any answers to the above. peace

 

[Sanchez1234]

Hi people. Can we please cleat up this seti issue with all the supposed different versions?

According to my sources there is the acid version, a sodium version(?) a salt version and according to one member a freebase.

can anyone (users/or not) clarify, simplify the above?)

The reason for this post is (to add to the confusion ) that chemical 'salts' are usually made in chemistry using various acids which would imply that the 'salted' version is the same as the acid version and people are just confusing chemical terminology?

this says nothing of course about the 'sodium' and the free-base' could we get this sorted out and clarified once and for all.

Finally do anyone have the precise chemical nomenclature for EACH version of seti to distinguish each and every form?

any help would be most appreciated!!!!!!!!!!!!!!!!!!!!!!!! merry xmas by the way- sorry to disturb your Xmas people and have a great new year.
I for one will do if i can get an any answers to the above. peace

From what i know there are 2 seti's: salted and acid.

I have tried both with same sides. So i think Kane was right when he told they both do the same.

But... @westonci has often talked about 'optimised' seti. This is the acid oral version but i don't know if it differs from normal acid seti?!

 

[Jonnyyy]

I got quoted 200g for $1150, is that good?

 

[Jonnyyy]

Yeah that's good. But you can go lower though...

Most importantly, is it good quality?

99.5% I asked for about 20g and they don't do under 50g=$400 want to make sure I don't get sides before I buy a big batch.

 

[SamFT]

99.5% I asked for about 20g and they don't do under 50g=$400 want to make sure I don't get sides before I buy a big batch.

I’m getting really tempted to buy some too

 

[theotherusero]

I have found on alibaba a cheap fevipiprant seller at 10-25$/gram and I'm considering it over seti.
I'm not very experienced, but for what I read fevi seems more promising than seti and since the daily dosage is 150mg and if the price on alibaba is right, it is also a lot cheaper.
What are your toughts?
It is a good choice?

 

[barfacan]

With oral fevi and seti, how do you ingest the solution?

Is it a whole thing like RU where you have to be a pharmacist and create it yourself or is the process simpler now?

it comes in powder form, iirc. So you can just cap it and ingest. Would definitely get purity tested prior to consumption from chinese labs, ofc.

 

[jamesbooker1975]

I have found on alibaba a cheap fevipiprant seller at 10-25$/gram and I'm considering it over seti.
I'm not very experienced, but for what I read fevi seems more promising than seti and since the daily dosage is 150mg and if the price on alibaba is right, it is also a lot cheaper.
What are your toughts?
It is a good choice?

Sounds too good to be truth. Are you planning to buy it and may be test it ? Another think that interesting me on Fevi, is, that if we have good luck, may be it don¡t pass the blood-brain barrier . I have no idea if so, could not find any info, but we know that seti do pass ( as many users report side effects on sleeping ) .

 

[jamesbooker1975]

With oral fevi and seti, how do you ingest the solution?

Is it a whole thing like RU where you have to be a pharmacist and create it yourself or is the process simpler now?

Almost all the synthesis are complex. I am a pharmacist and have not idea how to do it . In fact, people that actually do synthesis are, in general , graduates in chemistry . Like Walter White . What a pharmacist see on the university, about synthesis, it is simple to basic.

 

[CinnamonRoll]

I have found on alibaba a cheap fevipiprant seller at 10-25$/gram and I'm considering it over seti.
I'm not very experienced, but for what I read fevi seems more promising than seti and since the daily dosage is 150mg and if the price on alibaba is right, it is also a lot cheaper.
What are your toughts?
It is a good choice?

On paper, fevi should be more effective than seti mg/mg. And it should be cheaper as well.
Though "on paper" doesn't always translate to results. We know seti can work, fevi is technically unproven. But when you consider a fevi run is likely no more than 10% the cost of a seti run(and probably less than 3% the cost), it makes sense for anyone who's skipping seti based on price.