I think I'll just keep posting this every few pages or so. I might even head over to getitback.us and post it over there and see if I can destroy their forum with it.......here goes:
Posted: Tue Mar 27, 2007 8:22 pm Post subject:
--------------------------------------------------------------------------------
Charles Darwin,
http://en.wikipedia.org/wiki/Charles_Darwin, didn't use shampoo.
President John Adams,
http://en.wikipedia.org/wiki/John_adams
, didn't use shampoo
Hippocrates,
http://en.wikipedia.org/wiki/Hippocrates , didn't use shampoo
Francis Galton,
http://en.wikipedia.org/wiki/Francis_Galton , didn't use shampoo.
Benjamin Frankilin,
http://en.wikipedia.org/wiki/Benjamin_franklin , didn't use shampoo.
Socrates,
http://en.wikipedia.org/wiki/Socrates , didn't use shampoo
A balding Roman senator wrote a book about baldness. Baldness, and thinning hair, was very prevalent amongst Rome's ruling class. The first known remedy for baldness found in history was a mixture of crocidile fat and hippopotamous dung in ancient Egypt. Egyptians often wore wigs. Other ancient cultures featured wigs to hide baldness. George Washington, our first president, wore a wig to hide his baldness.
You can view pictures like this one,
http://www2.oprah.com/tows/slide/200509 ... _106.jhtml , that show TWO IDENTICAL FEMALE TWINS, with one twin using testosterone, and her ensuing male pattern baldness. This pic,
http://www2.oprah.com/tows/slide/200509 ... _107.jhtml , is very telling about what happens when girls take testosterone.
Note, ..........its funny how her new beard does not fall off like her temples despite being washed with soap. For those of you who dont know, soap is much stronger on average than shampoo.
Studies of women who take testosterone show that they go male pattern bald at the same incidnece statistically as men, with the same pattern.
http://joe.endocrinology-journals.org/c ... /180/1/107
Here is a picture of a woman before and after she got on testoserone therapy, http://images.google.com/imgres?imgurl= ... n%26sa%3DN
She shaves her body and head now (her head is bald now, and she shaves it), has a beard, and chest hair if you take the time to read about her. Note the facial ageing. This is a common feature of women who get on testosterone therapy. Testosterone ages the dermis. Hair is a dermal tissue.
Testosterone therapy produces body hair, facial hair (real beards) and hairloss in the male pattern in females if they have baldness genetics in their family histories. Women have all the genes necessary to go bald like men do, the just dont have the testosterone.
Androgen receptor blockers that act locally or systemically can halt baldness. Spironolactone creams are used by physicians to successfully treat or halt the progression of male pattern baldness. Finasteride and dutasteride have been shown to increase hair counts drammatically. Men born without the alpha five reductase type two enzyme that converts testosterone into the eagerly-binding subform, DHT, never go bald or develop a great deal of body hair.
Sprionolactone creams have an opposite effect on body hair as they reduce it. They are used clinically in women who have hair on their faces they want to lessen or thin out with success. Ketoconazole tablets also have an anti-androgenic effect (block recetors and inhibit androgen formation) and are used in female hirsutism (excessive body and facial hair) with medical success. Flutamide, a receptor blocker that acts systemically, is often given to female transexuals. It drammatically decreases their body hair and saves their head hair from further loss, but has extreme effeminizing side effects.
Male pattern or androgen baldness can best be summed up by describing it as a process where androgen male hormones bind to head hair's androgen receptors (mainly DHT) and the hairs grow weaker because the dermal papilla's of the hairs release growth inhibitors instead of growth factors to the rest of the follicle. We have been able to identify many of these inhibitors. Some are thrombospondin, Fiberblast growth factor five, TGF_beta 1, 2, and 3. We have idnetified some of the growth factors that the papilla's release to the rest of the follicle also. For some reason, after a time, the immune system seems to get interested in the hair follicle, and marker cells gather around the papilla (hair root) in larger than normal numbers, and the immune system begins to have a moderate attack on the follicle. The immune system sends inflammatory cytokines like Protien Kinease C, TNF-alpha, and Interluekin 1 at the follicle as well as superoxides. Oxides are the primary ageing factors in human cells. Dermal fibroblasts seem to produce excessive collagen around individual follicles, and restrict their enlargement in the early anagen phases (there are eight substages of the anagen or growing phase). The collageneous deposits crosslink and become hard. The dermal papilla cannot enlarge and multiply keratinocytes, and small wiry hairs are produced. Collagenous "streamers" appear underneath the follilce in the next rest phase, and prohibit the downward migration of the follicle in its next growth phase attempt. The follicle is effectifvely boxed in and pushed near the skin's surface, where it will remain.
The skin's appearnace is altered by this point. A man is usually "shiny" bald by now. The fibrosis, or scarring of the skin, has made his scalp harder and thinner, with a fatty and water layer lost. After a long time of baldness, the shiny appearance "breaks" and the skin really gets aged looking, often resulting in liver spots and discoloration.
Human baldness is slightly differentiated from ape baldness by the immunological events that take place therein. Many apes commonly bald. Stumptailed Macaques, orangutans, Gorillas, Bonoboos, Chimpanzees, and others go bald on their heads in recurring predictable patterns. But they don't have the inflammation and fibrosis, and treatments like finasteride can bring back alot more hair in them than it can in us because the tissue around the follicle isn't microscopially scarred and the capillaries therein not irreversibly damaged. As much as a transexual who gets off hormones will see her body hair regrow, these apes can "get their hair back" with finasteride, RU58841 (topical receptor blocker), and other anti-androgenic topicals, where humans only regrow what was lost in the last couple of years and stop losing more hair with these treatments for the most part.
Baldness is an emotional occurence when it happens to young men, and in the rare case that it happens in women. Our diets may induce more androgens in dermal tissues by upping the activity of alpha five reductase, upping receptor expression, lowering production of sex-binding-hormone globulin (that carries about 98 percent of testosterone around in a "bound" and unusable form in most instances), and adding inflammation to our tissues. High glycemic index diets that produce insulin resistance (and thus more insulin) are probably to blame for increasing early onset baldness in Insustrial societies and in the far east. Less phytoestrogenic foods in traditional eastern diets like green tea, soya, phytosterols, fish oils, rice oils and the like may also remove some protective dietary influences against androgens. Foods that induce excessive insulin secretion are pastas, white breads, sugars, fructose syrups, processed foods, excessive starches, and synthetic fats.....which is pretty much the Western diet.
Shampoos are typically only on the scalp for less than one minute, the laureth sulfates and foaming ingredients therein are surficants and are not designed to penetrate the dermis and to rinse off cleanly with water. They certainly never damage body hair on males, and to suggest they damage head hair is ridiculous with traditional usage. Shampoos are much milder than body and hand soaps. Two shampoos have been shown to increase diameter of hairs and anagen percentages of hairs growing as well as decreases in sebum in tests. One were a class of shampoos that contain the aforementioned ketoconazole and the other contains an ingredient called piroctone olamine. Both decreased sebum. The Piroctone olamine is also a strong anti-oxidant. Pirictone olamine does not seem to have anti-androgenic effects in male rats, so its probably not anti-androgenic, and must inhibit sebum secretions by some other means
http://toxsci.oxfordjournals.org/cgi/co ... ct/16/1/31
Here is a copy of the study describing how ketoconazole and pirictone olamine shampoos can help you grow MORE hair,
Titre du document / Document title
Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations
Auteur(s) / Author(s)
PIERARD-FRANCHIMONT C. (1) ; COFFIN V. (1) ; HENRY F. (1) ; UHODA I. (1) ; BRAHAM C. (1) ; PIERARD G. E. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Dermatopathology, University Medical Center Sart Tilman, 4000 Liège, BELGIQUE
Résumé / Abstract
Hair shedding and hair thinning have been reported to be affected by dandruff and seborrhoeic dermatitis. The present study was conducted in 150 men presenting with telogen effluvium related to androgenic alopecia associated with dandruff. They were randomly allocated to three groups receiving each one of the three shampoos in the market containing either 1% ketoconazole (KTZ), 1% piroctone olamine (PTO) or 1% zinc pyrithione (ZPT). Shampoos had to be used 2-3 times a week for 6 months. Hair shedding during shampoo was evaluated semiquantitatively. Hair density on the vertex was evaluated on photographs using a Dermaphot. Trichograms were used for determining the anagen hair percentage and the mean proximal hair shaft diameter using computerized image analysis. The sebum excretion rate (SER, μg cm[-2] h[-1]) was also measured using a Sebumeter [R]. The three treatments cleared pruritus and dandruff rapidly At end point, hair density was unchanged, although hair shedding was decreased (KTZ: -17.3%, PTO: -16.5%, ZPT: -10.1%) and the anagen hair percentage was increased (KTZ: 4.9%, PTO: 7.9%, ZPT: 6.8%). The effect on the mean hair shaft diameter was contrasted between the three groups of volunteers (KTZ: 5.4%, PTO: 7.7%, ZPT: -2.2%). In conclusion, telogen effluvium was controlled by KTZ, PTO and ZPTshampoos at 1% concentration. In addition, KTZ and PTO increased the mean hair shaft thickness while discretely decreasing the sebum output at the skin surface
Summarizing, its my position that shampoos simply clean your scalp, and remove sebum which contains DHT that can be reabsorbed back in the scalp. Shampoo does not cause male baldness, male hormones, as shown by hundreds of experiments, and the belief of the entire scientific research community, causes male baldness. Indications that lessen male hormone's interaction with androgen receptor sites in head hairs or agents that overcome androgens effect and attempt to counteract skin damage caused by the immune system or provide growth factors to the follicle are what have been proven to help men's hair. Sebum secretions are not effective even when washing hair in alchohol as Klingman's research in the seventies show, so washing the hair does NOT MAKE MORE SEBUM.
Loony, kooky alternative baldness theories by neo-luddites is a regular feature of baldness websites. They recur from time to time. Some people have a hard time accepting that their genes are not "perfect" and go off looking for something to blame for their acne, weight gain, baldness, hirsutism, etc. As toothpaste does not cause cavities, as soap does not cause zits, as q-tips dont cause ear wax, as mouthwash does not cause bad breath, as razors dont cause whiskers,........shampoo does not cause baldness
