Stemson is going to use minipigs in the next stage of their hair cloning research

[trialAcc]

where did you get the information from? I appreciate your factual and rational approach

The interview follicle thought did with them last year (I believe its on that treatment chart they update as well). They said their target to be commercially available was 2025-2027.

 

[eeyore]

The interview follicle thought did with them last year (I believe its on that treatment chart they update as well). They said their target to be commercially available was 2025-2027.

Do you have a source for that? I don't remember such an interview nor am I able to find one. But I do remember an interview Dr. Terskikh did with Dr. Wolf where his ballpark estimate was a bit longer than 3-4 years, which would more or less line up with 2025-2027. I wonder if he has a good knowledge about which regulatory hurdles would apply to his product.

 

[trialAcc]

Do you have a source for that? I don't remember such an interview nor am I able to find one. But I do remember an interview Dr. Terskikh did with Dr. Wolf where his ballpark estimate was a bit longer than 3-4 years, which would more or less line up with 2025-2027. I wonder if he has a good knowledge about which regulatory hurdles would apply to his product.

You'll have to dig through the site for the interview but here is the chart; https://twitter.com/FollicleThought/header_photo

 

[eeyore]

Interesting. I think that sounds realistic. What do you think what will the price of this treatment be? I heard in a report that it should be comparable to a normal hair transplant

I don't think anyone really knows but Dr. Terskikh did say in an interview that he wanted to make it available at a "reasonable cost" but I'm doubtful about that considering all the manual labor involved unless they find a way to automate most if not all of it. I'd personally want around 10k grafts and expect/am preparing to have to pay around $200k.

 

[trialAcc]

Interesting. I think that sounds realistic. What do you think what will the price of this treatment be? I heard in a report that it should be comparable to a normal hair transplant

I'd assume it would start off a bit more expensive but yeah I think easily over 10k if a surgeon has to complete it. Then you'd also be looking at more expensive for the skill of the surgeon. You might have unlimited follicles but if they are put in looking shitty then it's really not a cure, is it.

 

[eeyore]

I'd assume it would start off a bit more expensive but yeah I think easily over 10k if a surgeon has to complete it. Then you'd also be looking at more expensive for the skill of the surgeon. You might have unlimited follicles but if they are put in looking shitty then it's really not a cure, is it.

I highly doubt they'd be even close to 10k as that's already way cheaper than a decent transplant now. Also having horribly placed/oriented hairs isn't desirable but it's better than not having hair, and you can just buzz that down and rock the buzzed look.

 

[Pls_NW-1]

To better understand stemsons approach...:

The newly lab-created follicles... are they identical to the follicles you already have? Or are they completely new, as they would be when you were born!?

I suggest the answer is that they are identical to the follicles you already have, because they are made from YOUR blood.

Also: does this mean stemsons therapy could give you a full coverage + natural density!?

Mh

 

[werefckd]

I would love to hear your (@werefckd) opinion on why you think Stemson will be effective.

I think, even, if it is working, it won't give you THE perfect hair (you had) because its not natural hair, more-over it's bioengineered.

Also, in vitro, androgens will just rip off those follicles if your androgen receptors (in general) are just too sensitive to them. Because of that the only REAL approach to male pattern baldness is to multiplicate the androgen insensitive hairs from the back, but we all now that this way it won't work.

Mh

With Stemson it will be hit or miss.

If they fail to produce a natural looking human hair in their studies and trails, they won't even bother to release the product.

OTOH, if the procedure works as planned, it will be able to cover all our scalp with FULL density, with any hairline we want (even lower than our original). Basically the holy grail.

 

[werefckd]

it is a webinar for investors and potential investors. To be a potential investor at fortunis Capital, you need 250k net worth and an annual salary of 100k. Introduce yourself as a potential investor who heard about it

Cool the bar is low, we should start throwing some and help the cause

 

[Pls_NW-1]

With Stemson it will be hit or miss.

If they fail to produce a natural looking human hair in their studies and trails, they won't even bother to release the product.

OTOH, if the procedure works as planned, it will be able to cover all our scalp with FULL density, with any hairline we want (even lower than our original). Basically the holy grail.

In vitro it sounds like a magic restoration procedure. I can't seem to find any problem lol. Hope it is like that! Do we have infos when they want to continue/start the preclinical trials?

Hope I will be able to "cure" my hairloss till then with medication

 

[werefckd]

In vitro it sounds like a magic restoration procedure. I can't seem to find any problem lol. Hope it is like that! Do we have infos when they want to continue/start the preclinical trials?

Hope I will be able to "cure" my hairloss till then with medication

It's not in vitro. They have developed their tech on mice with human skin - edit: human cells (DP cells).

They may have started pre clinical studies with the minipigs already. If not, they will start soon.

My guess is best case scenario they finish the studies with minipigs in the second half of 2022 and start planing the clinical trials from there.

 

[Pls_NW-1]

It's not in vitro. They have developed their tech on mice with human skin.

They may have started pre clinical studies with the minipigs already. If not, they will start soon.

My guess is best case scenario they finish the studies with minipigs in the second half of 2022 and start planing the clinical trials from there.

Science was able to clone hair on mice back then in the 90s, but there were always problems. Hope this time it will be succesfull! :fingers_crossed:

Thanks!

 

[Armando Jose]

It's not in vitro. They have developed their tech on mice with human skin.

They may have started pre clinical studies with the minipigs already. If not, they will start soon.

And then now they want multiply hair follicles on minipigs with human skin?
It is a fantastic idea imo

 

[werefckd]

Science was able to clone hair on mice back then in the 90s, but there were always problems. Hope this time it will be succesfull! :fingers_crossed:

Thanks!

Not true.

 

[werefckd]

Most people don't realize this but not even Tsuji was able to demonstrate he could create new hairs from scratch. In his famous 2012 paper they showed they created new bioengineered hairs but they also had to kill vibrissa hair follicles to extract the DP cells they used in the process.

So yea Tsuji could create a new hair BUT he also had to kill a hair for that. The net sum was zero.

Stemson is the first and only company so far that has demonstrated they can create new hairs from multiplied/differentiated DP cells. And I think that is the case for epithelial cells too.

 

[frank33]

Most people don't realize this but not even Tsuji was able to demonstrate he could create new hairs from scratch. In his famous 2012 paper they showed they created new bioengineered hairs but they also had to kill vibrissa hair follicles to extract the DP cells they used in the process.

So yea Tsuji could create a new hair BUT he also had to kill a hair for that. The net sum was zero.

Stemson is the first and only company so far that has demonstrated they can create new hairs from multiplied/differentiated DP cells. And I think that is the case for epithelial cells too.

Closer than ever!

 

[trialAcc]

For all the ppl that worry about the price !
are you for real?
We can transplant like 7 k folicels from our own donor zone . So you would need around 3 k folicels from stemson to get head full of hair .
(The illusion of hair full of hair...) so yeah that make it less a problem now.

Huh? These guys are promising a full restoration of hair, not an illusion. You'd need 30k~ graphs.

 

[Pls_NW-1]

Huh? These guys are promising a full restoration of hair, not an illusion. You'd need 30k~ graphs.

30k~ what?

 

[trialAcc]

30k~ what?

To give native density to a NW4-7 you need upwards of 50-60,000 hairs.

 

[Pls_NW-1]

To give native density to a NW4-7 you need upwards of 50-60,000 hairs.

Ah sorry, I was reading "graphs", but you meant grafts lol. Yes! Thats for sure!