If people want an early indicator of it working I would say the best thing to look out for is the burning sensation you get, for me it happens a lot on my vertex and crown area, weirdly i notice it after having a cold shower and washing my hair. I cant feel it necessarily on its own but when I put my fingers on there it feels like a warm inflamed area right where the hair is thinning. Ive never had an itch so its hard for me to say with that but I know the warm spot on the bald spot is real and with this being a direct cause of the inflammation happening with the hair loss rather then the hair loss itself which can take a while to spot if looking for improvement it may be a good instant indicator for people to look out for