Tsuji - News Successfully Developed An Expansion Method Of Hf Derived Stem Cells

[razzmatazz91]

No, It will be a question of time. I'm not being optimistic, rather very realistic. Hair cloning is a reality one cannot deny;is here.

Is here?
You mean is an idea being researched, right?
That company HairClone.... Doesn't seem a good bet. Has 10 employees or less. Seems more like a sham company meant only to raise funds through investors and crowdfunding.... Rather than to actually research and carry out trials.

Are there any other, more reputable companies/people working on this?

I'll declare here that I don't want to be a buzzkill. I honestly hope for cloning to become a reality. But I can't deny facts...

 

[Endmymisery]

No, It will be a question of time. I'm not being optimistic, rather very realistic. Hair cloning is a reality one cannot deny;is here.

I think you're a bit too optimistic fam

 

[dermrafok]

I think you're a bit too optimistic fam

Sorry but no. I'm just realistic.

 

[sadila]

Sorry but no. I'm just realistic.

Realistic is knowing that the possibility of 'hair cloning' has been known for over 15 years, and the possibility of making it a cure for everyone is still as slim as it was 15 years ago.

 

[dermrafok]

Realistic is knowing that the possibility of 'hair cloning' has been known for over 15 years, and the possibility of making it a cure for everyone is still as slim as it was 15 years ago.

Don't worry man. You will see it.

 

[razzmatazz91]

Don't worry man. You will see it.

When's the next study/trial result due?

 

[razzmatazz91]

@razzmatazz91 bhai aaz zada tension me lag rahe ho. Meri condition tumse kahin buri hai. Ias k chkar me job chodi aur 4 saal ki tayari me saare baal bhi gaye. Ab is look k saath bahar niklne ka man nhi karta. Propecia be bhi gadbad ki khair wo theek ho gaya. So ab 32 saal age, bald and unemployed. Ias bhi nhi nikla. But kya kar sakte ho yar. Zitna likhwa kar laye hain utna dukh jhelna Hi pdega na.
Aap bhi gauravhouse k pass chalo kisi din Delhi me. Sayad kaam ban zaye.

That's a sad story. Sorry bro.
What is Gauravhouse?

 

[champpy]

@razzmatazz91 bhai aaz zada tension me lag rahe ho. Meri condition tumse kahin buri hai. Ias k chkar me job chodi aur 4 saal ki tayari me saare baal bhi gaye. Ab is look k saath bahar niklne ka man nhi karta. Propecia be bhi gadbad ki khair wo theek ho gaya. So ab 32 saal age, bald and unemployed. Ias bhi nhi nikla. But kya kar sakte ho yar. Zitna likhwa kar laye hain utna dukh jhelna Hi pdega na.
Aap bhi gauravhouse k pass chalo kisi din Delhi me. Sayad kaam ban zaye.

What, 32??? Are you kidding me

 

[RoyMunsonned]

Sorry but no. I'm just realistic.

What has Tsuji actually demonstrated up to now? I understand what his basic method is (put two types of cell in the same place and wait) but has he actually made a single working human follicle grow from scratch?

 

[MrV88]

What has Tsuji actually demonstrated up to now? I understand what his basic method is (put two types of cell in the same place and wait) but has he actually made a single working human follicle grow from scratch?

İsn't the plan to mutiply existing follicles from the donor area and not growing some from scratch?

 

[razzmatazz91]

Gaurav wig House.

Nope. Better to be bald than wear a wig.

 

[MrV88]

Nope. Better to be bald than wear a wig.

Amen brother

 

[RoyMunsonned]

İsn't the plan to mutiply existing follicles from the donor area and not growing some from scratch?

It's not multiplying follicles as far as I'm aware, if that means dissecting one and having the two parts turn into full follicles. My rough understanding of his method is to isolate two types of cell and multiply them through many generations, then make lots of little 'packets' containing these two types of cell that each develop into a new follicle. And I'm aware of hair having been grown on a hairless mouse's back. But I'm not clear on what has actually been proven with the human version of these cells.

 

[MrV88]

It's not multiplying follicles as far as I'm aware, if that means dissecting one and having the two parts turn into full follicles. My rough understanding of his method is to isolate two types of cell and multiply them through many generations, then make lots of little 'packets' containing these two types of cell that each develop into a new follicle. And I'm aware of hair having been grown on a hairless mouse's back. But I'm not clear on what has actually been proven with the human version of these cells.

I was just simplifying that Tsuji won't create new follicles from scratch.

As far as I know the hair on those mice were from human and not mice cell? Really have to read this again haha

 

[forlorn]

I was just simplifying that Tsuji won't create new follicles from scratch.

As far as I know the hair on those mice were from human and not mice cell? Really have to read this again haha

You are correct, they transplanted human hair follicles onto a mouse. The hair follicles grew successfully, and considering that they made human hair follicles grow using a mouse (meaning the method is compatible between species), it would certainly explain why they're setting the commercial release date as early as 2020.

"Painstaking research began with the bioengineering of various types of hair-follicle germs, which were grafted onto bald mice. The germs carried tiny nylon guides to nudge the growing hairs in the right direction.

Once that proved successful, the team moved on to bioengineering human hair-follicle germs and transplanting them in mice.

The human hairs grew in 21 days with the correct shafts, inner root sheaths and surrounding cells that normal human hair would, the study said.

Further tests proved the human hairs were, indeed, human."

Sources:
https://www.nature.com/articles/ncomms1784
https://www.thestar.com/news/world/...ese_scientists_regrow_human_hair_in_mice.html

 

[MrV88]

You are correct, they transplanted human hair follicles onto a mouse. The hair follicles grew successfully, and considering that they made human hair follicles grow using a mouse (meaning the method is compatible between species), it would certainly explain why they're setting the commercial release date as early as 2020.

"Painstaking research began with the bioengineering of various types of hair-follicle germs, which were grafted onto bald mice. The germs carried tiny nylon guides to nudge the growing hairs in the right direction.

Once that proved successful, the team moved on to bioengineering human hair-follicle germs and transplanting them in mice.

The human hairs grew in 21 days with the correct shafts, inner root sheaths and surrounding cells that normal human hair would, the study said.

Further tests proved the human hairs were, indeed, human."

Sources:
https://www.nature.com/articles/ncomms1784
https://www.thestar.com/news/world/...ese_scientists_regrow_human_hair_in_mice.html

Do you maybe know what density exactly was reached within the mice experiment?

Worst case scenario: get a lot of mice, implent them your own hair through the Tsuji method and then transplant them like a hair transplant lol

 

[dermrafok]

Do you maybe know what density exactly was reached within the mice experiment?

Worst case scenario: get a lot of mice, implent them your own hair through the Tsuji method and then transplant them like a hair transplant lol

It will be like this more or less. At least in the primary stages. Do not expect a fantasy treatment.

 

[razzmatazz91]

Worst case scenario: get a lot of mice, implent them your own hair through the Tsuji method and then transplant them like a hair transplant lol

Poor mice. I'd do it though

 

[forlorn]

Do you maybe know what density exactly was reached within the mice experiment?

Worst case scenario: get a lot of mice, implent them your own hair through the Tsuji method and then transplant them like a hair transplant lol

"To achieve hair follicle regeneration at hair densities of 120 or 60–100 hair shafts cm−² of normal scalp or in FUT treatment, respectively, twenty-eight bioengineered hair germs were transplanted into a cervical skin circle with a diameter of 1 cm. At 14 to 21 days after transplantation, the bioengineered hairs were erupted at a high density of 124.0±17.3 hair shafts cm−² (n=3; Fig 2c)"

Any desired density is achievable. The experiment was done 3 times, and every hair that was transplanted onto the mouse grew. And as most people already know, Riken found out how to control hair color and thickness as well, so you could essentially buy yourself a scalp full of hair that is thicker than it is supposed to be. Although I suspect this will only work with NW7, who have very little hair and can therefore mask their original hairs with the much thicker ones better.

Source:
https://www.nature.com/articles/ncomms1784

 

[MrV88]

107-142 hairs/cm² is really a dream.

Does somebody know if there is a survival possibility for hairs that have been transplanted back into the donor?