Exploring The Hormonal Route. Hair=life.

JaneyElizabeth

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Q8: Can Bicalutamide Increase Testosterone Levels More Than it Can Block Them?​

The increase in testosterone levels with bicalutamide monotherapy will never exceed the antiandrogenic actions of bicalutamide in terms of androgen receptor activation, as upregulation of testosterone production is merely a compensatory/homeostatic effect to make up for an apparent deficit. In other words, bicalutamide will not increase testosterone levels more than it can block them. The same applies to DHT. See here for some discussion on this topic.

If you click the link, huge explanation is coming up from Reddit post. You can check it out.
Stealing my thunder, huh? No, I am thrilled to see someone else obsessed with all of this.
 

JaneyElizabeth

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Stealing my thunder, huh? No, I am thrilled to see someone else obsessed with all of this.
Excellent information by Aly who is a stud or a mare rather. But the intracine synthesis of DHT from follicles on the face and scalp is key to the answer as to why some things work better with duta. Virtually all MtF's with insurance use Duta nowadays, I think.
 

JaneyElizabeth

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Folks should look into the hair plucking studies and those related to tissue regeneration by micro-needling for new insight into pertinent issues.
 

JaneyElizabeth

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Folks should look into the hair plucking studies and those related to tissue regeneration by micro-needling for new insight into pertinent issues.
Or Estrogen and wound healing which might be another good reason to use Estrogel, to reduce inflammation which seems to be along with DHT, the second key factor in hair loss.
 
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JaneyElizabeth

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Many blacks have almost perfect skin into their 80's and on due to the protective factors in their skin pigment. I think that whites can in essence roll back the clock via facial derma-rolling which I always do when doing my hair. It can likely remove freckling and age spots as well as withered or shrunken skin. It can probably even out cellulite which is a very common side effect of HRT. But MtF's like it, bizarrely enough, just like huge breasts and lips and nipples cause it reaches a point where no guy would have that.
 

JaneyElizabeth

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Posted by
u/JaneyElizabeth

7 hours ago


Clarification about Monotherapy with Either CPA, MPA, spironolactone or the 'Mides and Safety​

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I know many people do this in the XY hair loss community, in terms of only using an AA, which technically, duta and finasteride are too. I have been told that it can cause loss of bone mass and have other negative effects but I don't want to warn them off if unnecessary. It appears to me that Provera and CPA work exactly alike but we mostly use provera as an adjunct for breast finishing. So that would seem to leave spironolactone and bica as primarily receptor blockers.
If any of them raise E and lower T enough, then they should be safe in monotherapy or no? That's their thought as I always warn against more than 90 days single-shot AA.
 

JaneyElizabeth

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Changing my two patches for a new week. I use two generic Climara 100's. I usually place on buttocks or in the kidney area where they seem to stay better. Arguably the best method of ingestion among all who have insurance since they are pricey.
 

JaneyElizabeth

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I am waiting for some answers on my single-shot reddit question on reddit. If any of you know the answer please feel free to post over there.
 

deathdiss

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I am trying to find a scheme that does not lower the T to the female levels. Otherwise, we will get a feminization of the face, body changes. Bicalutamide is good at this, any scheme should include it as a base. It is possible to defeat hair loss with 100mg of Bika and dutasteride for sure, but the price of this treatment is very high, so I am looking for other options. At cost, I can afford the following options:
1) 75mg Bica + finasteride / Duta (if I find a generic)
2) 50mg Bica + finasteride + Estradiol. Estrogel is expensive if you use 2 clicks a day (1 press - 2.5g, 80g in a can). But I don't know what effect one press will have (0.75mg estradiol)

It is very difficult to choose. While I check all the options, I'll go bald


do you have to stick on bica for life or is it a cycle only?
 

JaneyElizabeth

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I don't really know lol. "Whatevr" has posted about it. Apparently it's present in the follicle of hairs that aren't miniaturizing and slowly dwindles away after puberty for those with balding scalps.
So many things seem apparent conceptually but then they just don't pan out.
 

ReturnOfExtreme

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Hair growth and facial feminization and breast growth all are going really well. Lowered my dose of oral min to ~6mg down from 12.5mg to hopefully decrease periphery hair increases. Is yours holding up?

That’s good to hear, any images of your hair for updates? And, mine is doing fine, I had a shed when increasing my estrogen dosage but that was expected
 

ReturnOfExtreme

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Explain the side effects. Have you become physically weaker, lost muscles? Are you getting fat? ED?

Physically weaker? Yeah. Lost muscles? Yeah. Didn’t have those regardless. Getting fat? No, but my weight has increased due to thicker thighs, etc. Erectile dysfunction? Don’t know, don’t use it.
 

JaneyElizabeth

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Anyone have a good source for a 2.5mm derma-roller on Amazon. I am getting frustrated because it only returns results for 0.25mm grrr.
 

JaneyElizabeth

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That’s good to hear, any images of your hair for updates? And, mine is doing fine, I had a shed when increasing my estrogen dosage but that was expected
Last ones were February 1st so I will post on my next good hair day which I still have strangely enough. My main need is volume. Any thinning areas are from a transplant that didn't take but derma-rolling can resolve that which is miraculous to me. The other theory of mine is cross-talk which increases blood flow in the follicles that weren't transplanted and even those that took. This would explain why small scars seem not to be visible through a full head of hair.
 
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