Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
- Start date
Switch hitting?
- Reaction score
- 678
So what?
- Reaction score
- 310
Metformin, lowers insulin, IGF-1 and DHEA.
I know I sound like a broken record but I want everyone to know there is a medication that basically takes care of the other big three killer hormones for hair.
- Reaction score
- 310
God's kind of a f*****g c*** to make men who are so androgen sensitive that it ruins their hair.
So, I would say that either god isn't so godly, or they're trusting in people to make the best decisions for themselves, and my god, imagine believing that men don't have estrogen coursing through their bodies as well as testosterone.
- Reaction score
- 509
Do you think i should take metformin just like that?
Can it exacerbate diabetes if you quit?
- Reaction score
- 310
Here's the thing, if you have absolutely no indication of insulin resistance, and no indication of excessively high or even mid-high insulin/igf-1 levels, I would say it is still acceptable to take metformin, but at a low dosage.
IMO metformin has gotten a horrendous reputation for bad sides because it was a drug that came out around the time boomers were ruining their bodies with terrible eating habits and developing full blown diabetes. So doctors were basically like: "Here, take a fuckton of it to treat your extreme diabeetus", and of course people got awful sides and doctors did not tell them you must, absolutely must supplement vit-b12 and folate because metformin will deplete you of both if you don't.
2 grams of metformin is stupidly high, and I would say just as a preventative you should be taking somewhere in the realm of 250-300mg of metformin if you are trying to lower certain hormones. If you can tolerate more titrate up. I would not exceed a gram in most cases, as that's when you get into side effect territory.
My Doctor wants me to take one last hormone panel before they put me on it, that will dictate my initial dose, but yes, I'm 100% going to try it because at this point I'm certain that testosterone is not my problem with regard to hair loss.
I'm pretty sure it's a matter of insulin/igf-1 and -maybe- DHEA, but I believe a lack of proper growth factors is a mitigating factor.
That's minoxidil territory, or PRP, but PRP is dummy expensive and I would not recommend doing what I did and get it once per month, it hurts all to hell and it's extremely expensive, but it absolutely -did- work, I just think that minoxidil would work just as well if I could get a dose that won't give me sides.
IMO metformin has gotten a horrendous reputation for bad sides because it was a drug that came out around the time boomers were ruining their bodies with terrible eating habits and developing full blown diabetes. So doctors were basically like: "Here, take a fuckton of it to treat your extreme diabeetus", and of course people got awful sides and doctors did not tell them you must, absolutely must supplement vit-b12 and folate because metformin will deplete you of both if you don't.
2 grams of metformin is stupidly high, and I would say just as a preventative you should be taking somewhere in the realm of 250-300mg of metformin if you are trying to lower certain hormones. If you can tolerate more titrate up. I would not exceed a gram in most cases, as that's when you get into side effect territory.
My Doctor wants me to take one last hormone panel before they put me on it, that will dictate my initial dose, but yes, I'm 100% going to try it because at this point I'm certain that testosterone is not my problem with regard to hair loss.
I'm pretty sure it's a matter of insulin/igf-1 and -maybe- DHEA, but I believe a lack of proper growth factors is a mitigating factor.
That's minoxidil territory, or PRP, but PRP is dummy expensive and I would not recommend doing what I did and get it once per month, it hurts all to hell and it's extremely expensive, but it absolutely -did- work, I just think that minoxidil would work just as well if I could get a dose that won't give me sides.
- Reaction score
- 310
If you go off metformin, your insulin sensitivity and insulin and IGF-1 levels will simply creep back up again, it's one of those drugs that if you want the long-term benefits, you have to be on it for life, so the key is knowing what you can tolerate versus just bombing yourself with doctor recommended doses.
Doctors are just as much modern clerical workers than anything, a lot of them don't have the time to look up and invest time in researching the effects of all the drugs they prescribe. It's like most teachers these days, they just get the curriculum from the government and repeat what it says.
There are some good doctors that understand things a bit better but many of them are so rare that it's far better for you to do the research on your own.
Metformin is definitely one of those drugs that you absolutely have to be careful with, as with many overdosed drugs, the bad sides come from the fact that it builds up cumulatively.
There are some people who use metformin as a preventative, so I hardly think taking it as somebody without diabetes will give it to you if you go off it, but it absolutely can prevent the onset from even occurring and the resultant damage.
It's just you absolutely must respect the medication and realize that more isn't better.
Doctors are just as much modern clerical workers than anything, a lot of them don't have the time to look up and invest time in researching the effects of all the drugs they prescribe. It's like most teachers these days, they just get the curriculum from the government and repeat what it says.
There are some good doctors that understand things a bit better but many of them are so rare that it's far better for you to do the research on your own.
Metformin is definitely one of those drugs that you absolutely have to be careful with, as with many overdosed drugs, the bad sides come from the fact that it builds up cumulatively.
There are some people who use metformin as a preventative, so I hardly think taking it as somebody without diabetes will give it to you if you go off it, but it absolutely can prevent the onset from even occurring and the resultant damage.
It's just you absolutely must respect the medication and realize that more isn't better.
- Reaction score
- 63
Resveratrol may help reduce adrenal androgens.
Do you know your androstenedione level?
Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4-month randomised trial in middle-aged men: Resveratrol Reduces the Levels of Circulating And
Request PDF | Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4-month randomised trial in middle-aged men: Resveratrol Reduces the Levels of Circulating Androgen Precursors | Background...
www.researchgate.net
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- Reaction score
- 310
That sounds good, the only thing I would be careful of is the fact that it behaves like an antioxidant, and yes oxidative stress can hurt hair, but taking too much of any antioxidant will impede hair growth, but that's a good bit of info, I'll have to try resveratrol again.
- Reaction score
- 1,104
I think this might help me:
1,25mg Finasteride
50/100mg Bicalutamide
(2,5mg Minoxidil)
500/1000mg Metformin
500/1000mg Resveratrol
This combo should be it.
I wonder if I can keep this treatment regimen for ever. Might use dutasteride instead of finasteride.
1,25mg Finasteride
50/100mg Bicalutamide
(2,5mg Minoxidil)
500/1000mg Metformin
500/1000mg Resveratrol
This combo should be it.
I wonder if I can keep this treatment regimen for ever. Might use dutasteride instead of finasteride.
- Reaction score
- 1,104
My T is almost lower than the normal range should be and my E2 is reaching almost the highest possible of the normal range, I am confused. I wonder what's the levels of all my other androgens.
If T is literally that low, and there's low DHT because of finasteride in the next blood test, 50mg bica will carry me for life lol.
If T is literally that low, and there's low DHT because of finasteride in the next blood test, 50mg bica will carry me for life lol.
Yes, I have the same thing. Hair first becomes thinner and then disappearsView attachment 157971
Sorry for overrunning this thread all and all over again
But is this Miniaturization along the hairline/temples? Yes, right?
- Reaction score
- 1,104
Wow, my whole frontal hair got thin, especially the corners, starting to develop a V-line... rip.
- Reaction score
- 414
After spending hours reading the side effects of bicalutamide, knowing its nuclear potential.
I decided to try 25mg a day and see what happens, if in 60 days I don't see any difference increase to 50mg.
I've been on e2 doses ranging from 0.75mg to 4mg e2 per day (some days I took more, others less) for 100 days
It improved my skin insanely, maybe at first it was helping, but then it stopped , 100 days without regrowth
My theory in some cases is that e2 alone will bring down our dominant sex hormone too much and we need a dominant sex hormone for regrowth whether it's testosterone or projesterone.
Explains a lot why women in combined anti-conception therapy improve their hair (high progesterone and E2)
And Bodybuilders also do the same thing (high T and high E2) feel gyno, hair growth and other side effects.
I can not explain the mechanism of action at this point what I can say and that even blocking the receptors the hormone has several ways of acting in the body.
So I think that in the end, after so much thinking, digressing and analyzing, maybe bicalutamide is the best nuclear choice for CISman.
Bicalutamide will high your levels of E2 and T.
After wasting hours reading thousands of studies it is generally hepatoxically safe in the long run I would say up to 50-75mg.
Gyno the only problem in the scheme and maybe AR receptor Sensitive , but finasterida can do it too .
I will titrate 25mg of bicalutamide with 1 mg finasteride to start and feel my breasts.
I will remove the exogenous E2 from the therapeutic regimen (I bought 4 tubes
)
I'm not saying it's forever, maybe I'll cycle e2 with them in the future to bring my T levels down, if necessary.
Bicalutamide will preserved fertility , finasterida too , The only problem is the semiferiferous tubes, but spermatogenesis is preserved .
Is this , you are despair ?
Finasterida can't hold your baldness ?
Dutasterida can't hold your baldness ?
Spirolactone can't ? ( for me is crazy for the electrolytic imbalance (death) it causes and precocious aging (real) but you can try)
Flutamida Suicide
Enzalutamida and analagous , Suicide
Microneedling can't ?
Didn't even the Prayers do it?
Helmet with laser, soy, standing upside down, crying, didn't any of this work?
Are you a guy and like your testosterone? likes to behave like a man and the stuff sex and yet you have tried e2 title together with all the others and didn’t get a result ,and you stay in nw2 ? nw3 ?
E2 do nothing ?
This is the last thing before a complete MTF treatment (CPA , MPA , and all the things we will destroy your T and axis HPT)
In some cases E2 will help in others no .
Note high's level of testosterone is not so good , need check this (IGF-1 and others side effects)
Try Bicalutamide with 5ar blocker and minoxidil
(Need exams , check your T before )
If that doesn't work, your baldness is probably not androgenic or just complete MTF treatments will do something.
Lets move , Good luck my friends
I decided to try 25mg a day and see what happens, if in 60 days I don't see any difference increase to 50mg.
I've been on e2 doses ranging from 0.75mg to 4mg e2 per day (some days I took more, others less) for 100 days
It improved my skin insanely, maybe at first it was helping, but then it stopped , 100 days without regrowth
My theory in some cases is that e2 alone will bring down our dominant sex hormone too much and we need a dominant sex hormone for regrowth whether it's testosterone or projesterone.
Explains a lot why women in combined anti-conception therapy improve their hair (high progesterone and E2)
And Bodybuilders also do the same thing (high T and high E2) feel gyno, hair growth and other side effects.
I can not explain the mechanism of action at this point what I can say and that even blocking the receptors the hormone has several ways of acting in the body.
So I think that in the end, after so much thinking, digressing and analyzing, maybe bicalutamide is the best nuclear choice for CISman.
Bicalutamide will high your levels of E2 and T.
After wasting hours reading thousands of studies it is generally hepatoxically safe in the long run I would say up to 50-75mg.
Gyno the only problem in the scheme and maybe AR receptor Sensitive , but finasterida can do it too .
I will titrate 25mg of bicalutamide with 1 mg finasteride to start and feel my breasts.
I will remove the exogenous E2 from the therapeutic regimen (I bought 4 tubes
)I'm not saying it's forever, maybe I'll cycle e2 with them in the future to bring my T levels down, if necessary.
Bicalutamide will preserved fertility , finasterida too , The only problem is the semiferiferous tubes, but spermatogenesis is preserved .
Is this , you are despair ?
Finasterida can't hold your baldness ?
Dutasterida can't hold your baldness ?
Spirolactone can't ? ( for me is crazy for the electrolytic imbalance (death) it causes and precocious aging (real) but you can try)
Flutamida Suicide
Enzalutamida and analagous , Suicide
Microneedling can't ?
Didn't even the Prayers do it?
Helmet with laser, soy, standing upside down, crying, didn't any of this work?
Are you a guy and like your testosterone? likes to behave like a man and the stuff sex and yet you have tried e2 title together with all the others and didn’t get a result ,and you stay in nw2 ? nw3 ?
E2 do nothing ?
This is the last thing before a complete MTF treatment (CPA , MPA , and all the things we will destroy your T and axis HPT)
In some cases E2 will help in others no .
Note high's level of testosterone is not so good , need check this (IGF-1 and others side effects)
Try Bicalutamide with 5ar blocker and minoxidil
(Need exams , check your T before )
If that doesn't work, your baldness is probably not androgenic or just complete MTF treatments will do something.
Lets move , Good luck my friends
Last edited:
- Reaction score
- 1,104
Impressive post! Thank you!After spending hours reading the side effects of bicalutamide, knowing its nuclear potential.
I decided to try 25mg a day and see what happens, if in 60 days I don't see any difference increase to 50mg.
I've been on e2 doses ranging from 0.75mg to 4mg e2 per day (some days I took more, others less) for 100 days
It improved my skin insanely, maybe at first it was helping, but then it stopped , 100 days without regrowth
My theory is that e2 alone will bring down our dominant sex hormone too much and we need a dominant sex hormone for regrowth whether it's testosterone or projesterone.
Explains a lot why women in combined anti-conception therapy improve their hair (high progesterone and E2)
And Bodybuilders also do the same thing (high T and high E2) feel gyno, hair growth and other side effects.
I can not explain the mechanism of action at this point what I can say and that even blocking the receptors the hormone has several ways of acting in the body.
So I think that in the end, after so much thinking, digressing and analyzing, maybe bicalutamide is the best nuclear choice for CISman.
Bicalutamide will high your levels of E2 and T.
After wasting hours reading thousands of studies it is generally hepatoxically safe in the long run I would say up to 50-75mg.
Gyno the only problem in the scheme .
I will titrate 25mg of bicalutamide with 1 mg finasteride to start and feel my breasts.
I will remove the exogenous E2 from the therapeutic regimen (I bought 4 tubes
I'm not saying it's forever, maybe I'll cycle e2 with them in the future to bring my T levels down, if necessary.
Bicalutamide will preserved fertility , finasterida too , The only problem is the semiferiferous tubes, but spermatogenesis is preserved .
Is this , you are despair ?
Finasterida can't hold your baldness ?
Dutasterida can't hold your baldness ?
Spirolactone can't ? ( for me is crazy for the electrolytic imbalance (death) it causes and precocious aging (real) but you can try)
Flutamida Suicide
Enzalutamida and analagous , Suicide
Microneedling can't ?
Didn't even the Prayers do it?
Helmet with laser, soy, standing upside down, crying, didn't any of this work?
Are you a guy and like your testosterone? likes to behave like a man and the stuff sex and yet you have tried e2 title together with all the others and didn’t get a result ,and you stay in nw2 ? nw3 ?
This is the last thing before a complete MTF treatment (CPA , MPA , and all the things we will destroy your T and axis HPT)
Try Bicalutamide with 5ar blocker and minoxidil
If that doesn't work, your baldness is probably not androgenic or just complete MTF treatments will do something.
Lets move , Good luck my friends
I was hearing someone who said that androgen deprivation therapy has a risk of heart failure!? @Almas @tato123 ??