Exploring The Hormonal Route. Hair=life.

Almas

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The following thought came to me: if you abandon HRT and stay on Bicalutamide, the changes will remain, because bicalutamide prevents masculinization
You will regain the ability to build muscle, your psychological state, if it changes with estrogen, your sexual function. However, face changes - here I am not sure
 
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tato123

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Ya Bica is old school according to history of AA's. Maybe we should be experimenting with the likes of Elagolix - the new game in town:

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Hi friend I'll take your post to say something, it's not for you personally :D

Incredibly, I tell, that I have studied all other presentations of non-steroidal anti-androgens too much, not only these, this whole class of medication.

I have a degree in health and I try to support everything I read and absorb about these guidelines.

I tell you that bicalutamide is the "best choice" despite being "oldscool" for thousands of reasons already discussed here and in the end it becomes an infinite repetition.

For example, in the case of the Elagolix that mentioned and marked, this is a GnRh antogonist, Its mechanism of effect has nothing to do with that of bicalutamide , that is, it will cause you a central hypogonadism by inhibiting its hypothalamic pathway, it will inhibit your hypophysis to secrete FSH and LH will cease your endogenous testosterone production. and that’s not what we’re looking for, it’s safer to take some derivative of prostagene, estrogen than you use a thing like this.

it is safer for you to take estrogen to end your HPT axis signaling than to tamper with this type of GnRh modulator.

This will have thousands of side effects, and it will be strictly necessary to do hormone replacement if it is not suicide right, it will do too much harm to your head.

This has already been discussed so much here, CPA, enzalutamida, flutamida , elagolix , espinorolactone , bla bla bla and other analogs have different mechanisms of action between them, at the end all of this list despite being used to deal with the same thing sometimes has different mechanisms of action.

And we use these drugs always off-label, that is, the studies conducted by the drug laboratory did not study it for this.

I think our conversation has to be about results, how do we hit our goals?

What did you use and how did you get results?

In the end I think that this forum becomes an eternal repetition, I think that all the content we need to reach the cure is already here, just need search , and have the courage to do something , since it bothers us so much and we spend so many hours here.

Now answering, in my opinion bicalutamide is the safest today among those nuclear bombs mentioned, besides being a nuclear weapon too, but I prefer it than others.
 

Nimos0651

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The following thought came to me: if you abandon HRT and stay on Bicalutamide, the changes will remain, because bicalutamide prevents masculinization
You will regain the ability to build muscle, your psychological state, if it changes with estrogen, your sexual function. However, face changes - here I am not sure
Do you have any data to back this up? I am looking into possibly taking Bica instead of spironolactone and keeping low dose E
 

Pls_NW-1

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Its just his educated assumption, which I agree with. There is no data. Even if you take ALL people on this site that took bica, none of them took the drug for longer than 5 years.
Because the first long term users started taking it first in 2018, that's why.

And I totally agree with Almas. Right now there is no return from HRT in terms of hairloss, Noah is like an anomaly.

Only if topical AR degraders come true. You could do HRT, regrow hair as much as possible, stop HRT, while retaining hair with topical AR degrader, and then after getting to baseline in terms of masculinization, you can start again solo bica or just keep the topical AR degrader.
 

Nimos0651

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It would actually be good to have good density lmao
If AR degraders actually happen, there will be no need for HRT. If you stop your hairloss early you will have endless donor supply for H.T on your whole head.
I am only taking 1mg estradiol orally + .75mg estrogel with 50mg spironolactone. Is this enough to permanently feminize me? I am a cis male and want to avoid as much feminization as possible.
 

nameless2

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You know, I am mostly a non-believer in everything except HRT meds and oral minoxidil meaning nothing else essentially has any effects on hair at all or cosmtically significant. But I mean, I don't care. Estrogen plus cannabis equals heaven for me and I deem it a gift from Our Lady Above.<winks>

It makes me happy:


Cool song. It reminds me of another song but I can't remember the name of it.

UPDATE: I just remembered the name of the old song that reminds me of Sherryl Crow's "If it makes you happy". It's a song called ""Lotta Love" by Nicollette Larson. The songs seem similar in parts of the song but the similarity is striking in a few lines of the two songs. It's Crow's line, "If it makes you happy it can't be that bad" AND Larson's line, "My heart needs protection and so do I". It's Crow's line (again), "If it makes you happy it can't be that bad" AND Larson's line, "You know I need relating not solitude." Check out Larson's song below and pay special attention to those 3 lines.

 
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JaneyElizabeth

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Cool song. It reminds me of another song but I can't remember the name of it.

UPDATE: I just remembered the name of the old song that reminds me of Sherryl Crow's "If it makes you happy". It's a song called ""Lotta Love" by Nicollette Larson. The songs seem similar in parts of the song but the similarity is striking in a few lines of the two songs. It's Crow's line, "If it makes you happy it can't be that bad" AND Larson's line, "My heart needs protection and so do I". It's Crow's line (again), "If it makes you happy it can't be that bad" AND Larson's line, "You know I need relating not solitude." Check out Larson's song below and pay special attention to those 3 lines.

Why thank you. I love the Crow song so much.
 

Androgenic Alpaca

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There is nothing that could actually permanently feminize you. In your case I would worry more about longterm health of your testes and gyno that you would have to get surgery for it.

Yes hrt can "permanently" feminize you. If you stop hrt and start megadosing androgens you'll re-masculinize but you'll have lingering effects from HRT. Obviously gyno which has to be surgically removed once it progresses past a certain point. But there will also be long-term effects in terms of facial feminization if you are on HRT long enough. If you take HRT for like 5 years and fully transition to female and then want to stop HRT and transition back to male, you'll have a lot of the difficulties that an FtM trans person will have. Obviously a MtFtM person won't have as a difficult a transition back to male as an FtM person but it's not a magic "I'm a dude again!" switch
 

Pls_NW-1

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There is nothing that could actually permanently feminize you. In your case I would worry more about longterm health of your testes and gyno that you would have to get surgery for it.
Agreed. If you want to still have "normal" testes, you need to drop the E in total asap.
 

Yar

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Смотря сколько вы используете эстрогена,я использую каждый день по 1 дозе или геля или таблетку.Да в каком то варианте это феменезировало меня,но все равно я остаюсь парнем.Ко мне везде обращаются как к парню.
 

Almas

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Do you have any data to back this up? I am looking into possibly taking Bica instead of spironolactone and keeping low dose E
Bicalutamide has been used in adolescents to prevent masculinization and has been successful in its task. This means that if you use Estrogen with Bicalutamide, and then leave Bicalutamide and remove Estrogen, Bicalutamide will prevent masculinization. This is my guess. I could be wrong.
 

Pls_NW-1

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Bicalutamide has been used in adolescents to prevent masculinization and has been successful in its task. This means that if you use Estrogen with Bicalutamide, and then leave Bicalutamide and remove Estrogen, Bicalutamide will prevent masculinization. This is my guess. I could be wrong.
Very true, nice post. Yes, if you want to remasculinize, you need to drop bicalutamide and use a topical anti androgen.
 

Notdifferent

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Cool song. It reminds me of another song but I can't remember the name of it.

UPDATE: I just remembered the name of the old song that reminds me of Sherryl Crow's "If it makes you happy". It's a song called ""Lotta Love" by Nicollette Larson. The songs seem similar in parts of the song but the similarity is striking in a few lines of the two songs. It's Crow's line, "If it makes you happy it can't be that bad" AND Larson's line, "My heart needs protection and so do I". It's Crow's line (again), "If it makes you happy it can't be that bad" AND Larson's line, "You know I need relating not solitude." Check out Larson's song below and pay special attention to those 3 lines.

Great song. This is not actually Nicolette's song, it's Neil Young's.


01E8363C00000514-3828037-image-a-42_1475886334979.jpg
 

Almas

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The chest stopped hurting, it only hurt for a few minutes, there were no signs of gynecomastia. I found myself resistant to gynecomastia
But I still need surgery, because I plan HRT next year to resume growth
Wish I wasted time on Finasteride. My hair has suffered a lot, now it's not enough just to keep it - I need an increase in density
 

JaneyElizabeth

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Density, volume and better texture with a long anagen phase so one can grow one's hair long. I am achieving all four of those. It's a weird feeling because on one hand, it's just a matter of time but you never know or at least you fear that the hair conks out before you reach your goals but I have pretty much done that. I would go back on maybe 50mg to 100mg of spironolactone just to see if that flips any more receptors. It's weird how AA's and estrogen can cause different things so often.
 
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