Realistic Expectation From Follica's Treatment

Jonnyyy

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Yeah, its just hair....
You know what? My uncle had a cancer. He is one of the lucky one where chemo and etc. worked. Still every time someone asks him how was it he says, that after while he had accepted the fact he will die soon. But what made it worst was,that he lost his hair and was no longer himself. By his words. Losing hair was worse than dying.
My point is, that cancer and similair shits sucks. But sometimes suffering, where you can see its end is better than knowing you lived good only 18 years and now 60-70 years of feeling and looking like sh*t is in front of you.
As stupid as it sounds that's how I feel, knowing I have like 60 years left but my prime is already over.
 

Janko

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As stupid as it sounds that's how I feel, knowing I have like 60 years left but my prime is already over.
Baldness kills you from the inside. You as you actually die, because of it. The person in the mirror is barely the same person.
 

NimuDash

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Possibly Replace a Finasteride / Minoxidil Regimen?
It's just a guess, but this is not a sign showing his treatment will bring back full density
https://www.hairlosstalk.com/news/new-research/follica-presents-at-the-aad-2017-annual-meeting/
Well, my guess is that it can grow as many hairs as you like repeating the process, but it cannot grow thick hairs due to androgenic activity still being present. Dermarolling wouldn't have worked that well for somebody if he was not on dutasteride. Modality is just a form of application or employment of a therapeutic agent or regimen, they are saying that the process will be different and cannot be compared since there are not enough studies and other sh*t.
 
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Jonnyyy

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Well, my guess is that it can grow as many hairs as you like repeating the process, but it cannot grow thick hairs due to androgenic activity still being present. Dermarolling wouldn't have worked that well for somebody if he was not on dutasteride. Modality is just a form of application or employment of a therapeutic agent or regimen, they are saying that the process will be different and cannot be compared since there are not enough studies and other sh*t.
"Androgenic activity" whaaaaaaat? You realize that it's not the area around the hairs or anything else that's the problem it's the hair follicles themselves that are genetically disposed to dying off with a certain amount of dht, and as your hair follicles become more sensitive to dht the easier they are to fall out. I don't believe them creating brand new hair follicles would make them become dht sensitive as well, I wouldn't doubt it that they need a certain something to keep them alive though wether that's wounding or something else. Which would make a lot of sense, getting a full head of hair back but having to constantly go back to the dermatologist office to have your head wounded in order to keep your hair follicles intact, smart.
 

BaldyBalderBald

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"Androgenic activity" whaaaaaaat? You realize that it's not the area around the hairs or anything else that's the problem it's the hair follicles themselves that are genetically disposed to dying off with a certain amount of dht, and as your hair follicles become more sensitive to dht the easier they are to fall out. I don't believe them creating brand new hair follicles would make them become dht sensitive as well, I wouldn't doubt it that they need a certain something to keep them alive though wether that's wounding or something else. Which would make a lot of sense, getting a full head of hair back but having to constantly go back to the dermatologist office to have your head wounded in order to keep your hair follicles intact, smart.

Pure speculations dude, Cots never mentionned this in any of his papers, i thought so too but after research on this, no evidence so far
That question was on the Hellouser list...damn, if only the guy would answer those questions we have
 
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coolio

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Hair follicles start accumulating androgen damage at puberty. And they got blasted with HUGE androgen levels at the time because it was puberty.

Did you go bald at 13? No. Even with that enormous androgen attack it still took at least a few years before you were worrying about hair loss.

It should take many years for Follica-grown hairs to accumulate the degree of androgen damage that made you come to this forum. Maybe a decade or more.
 

BaldyBalderBald

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Hair follicles start accumulating androgen damage at puberty. And they got blasted with HUGE androgen levels at the time because it was puberty.

Did you go bald at 13? No. Even with that enormous androgen attack it still took at least a few years before you were worrying about hair loss.

It should take many years for Follica-grown hairs to accumulate the degree of androgen damage that made you come to this forum. Maybe a decade or more.

Some people can go rapidly bald at every age (after start of puberty of course), your argument is kinda invalid, it's not the androgen levels that are in cause, it's the androgen receptors sensitivity, and science still don't know for sure what triggers an extreme sensitivity, at what age, and why some are less sensitive that others, and therefore will bald slowly.

It's all about the sensitivity, not the androgen levels...
 
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coolio

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It's the combination of both androgen sensitivity and androgen levels.

The follicles chronically accumulate androgen damage and it seems to snowball past a certain point. The fact is that men who "suddenly go bald" midway through their life were typically losing density long before that. The process sometimes abruptly speeds up but that is a matter of degree. You just don't see full-density guys at 32 being bald at 55. People sometimes claim it happens, but when you examine the case it always looks more like that 32yo "full density" was already affected. It just hadn't been depleted enough to show yet.

IIRC research shows that follicles which are denied the huge androgen exposure during puberty don't go bald later in life. The exposure during puberty "primes the pump" on the balding process.

I'm not optimistic enough to think Follica's hairs would be totally immune to androgenic damage but it will probably take at least several years before it's any kind of issue.

I have created a few new terminal hairs on my hairline from needling over the years. They are lasting much, much longer than the struggling native hair around them is.
 

BaldyBalderBald

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It's the combination of both androgen sensitivity and androgen levels.

The follicles chronically accumulate androgen damage and it seems to snowball past a certain point. The fact is that men who "suddenly go bald" midway through their life were typically losing density long before that. The process sometimes abruptly speeds up but that is a matter of degree. You just don't see full-density guys at 32 being bald at 55. People sometimes claim it happens, but when you examine the case it always looks more like that 32yo "full density" was already affected. It just hadn't been depleted enough to show yet.

IIRC research shows that follicles which are denied the huge androgen exposure during puberty don't go bald later in life. The exposure during puberty "primes the pump" on the balding process.

I'm not optimistic enough to think Follica's hairs would be totally immune to androgenic damage but it will probably take at least several years before it's any kind of issue.

I have created a few new terminal hairs on my hairline from needling over the years. They are lasting much, much longer than the struggling native hair around them is.

A bunch of friends of mine i know since high school started balding suddenly when they reach their early 30's, and believe me, they used to have a perfect head of hair, no sign of thinning or receiding, process just started like that, and it's going pretty fast, one particulary, 30 perfect hair, 32 NW3, and his father has a strong NW1.5 at 63.This sh*t is totally unpredictable
 
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coolio

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A bunch of friends of mine i know since high school started balding suddenly when they reach their early 30's, and believe me, they used to have a perfect head of hair, no sign of thinning or receiding, process just started like that, and it's going pretty fast, one particulary, 30 perfect hair, 32 NW3, and his father has a strong NW1.5 at 63.This sh*t is totally unpredictable

Density loss doesn't become visible/detectable until it's like 40-50% of the way gone. This is pretty well agreed-upon in the baldness and hair transplant world. The balding process always starts many years before a guy is recognized to be "thinning" or "receding."
 

BaldyBalderBald

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Density loss doesn't become visible/detectable until it's like 40-50% of the way gone. This is pretty well agreed-upon in the baldness and hair transplant world. The balding process always starts many years before a guy is recognized to be "thinning" or "receding."

Sure whatever, i heard that before, and this is true, but won't argue more since you seems quite convinced.
It took 15 years to became visible, then 2 years to go to NW3, his hairline was perfect until his 30's, i've seen the guy almost every weeks

"The proportion of men with moderate to extensive hair loss increased with increasing age, ranging from 16% for men 18-29 years of age to 53% of men 40-49. Twelve percent of the men were classified as having predominantly frontal baldness (type A variants)."

"Male pattern baldness or Androgenic Alopecia can begin at any age and to varying degrees. The question of when an individual will lose his or her hair is left solely up to genetics"

Ever heard the expression follicle ticking timebomb ?
 
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coolio

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Sure whatever, i heard that before, and this is true, but won't argue more since you seems quite convinced.
It took 15 years to became visible, then 2 years to go to NW3, his hairline was perfect until his 30's, i've seen the guy almost every weeks

I used to think it was possible too. But after over a decade of interest in baldness I don't think it is. Every case turns out to be somebody who didn't actually check for miniaturization, they just looked full-headed for a long time.


Who habitually checks for miniaturization when they are in their teens/20s and have absolutely zero signs of balding?

The guys in the internet baldness community are among the most baldness-obsessed and baldness-active guys in the world. How may of us were even checking such a thing 5 or 10 years before we suspected we were thinning?
 

BaldyBalderBald

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Who habitually checks for miniaturization when they are in their teens/20s and have absolutely zero signs of balding?

The guys in the internet baldness community are among the most baldness-obsessed and baldness-active guys in the world. How may of us were even checking such a thing 5 or 10 years before we suspected we were thinning?

Actually i do, having receiding hairline at 15, spending 15 years watching my friends hair every weeks, i would have seen it
You're too stubborn, believe what you want
 

coolio

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I had a receding hairline in my teens too. I was watching other guys' hairlines too.

But I wasn't plucking off hairs from different areas of their heads and comparing the thickness of hair shafts for miniaturization under magnification. That's what it really takes to spot early miniaturization.


Sorry to keep giving you crap about this but it's something that I feel strongly about it. IMO checking for miniaturization should be more understood and more common. There are exceptions to everything but IMO long-term balding is usually detectable many years before it gets visible. I think thousands of guys would be making better baldnesss treatment and hair transplant decisions if we all did more "early screening" for the problem. By the time it's visually noticeable at all, the process is already advancing past the most treatable stages.

The best time to fight baldness was back when our friends/family would have called us crazy to be thinking about it.
 

Balding curse

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I knew that I'm balding at 18, but I didn't expect that it's very aggressive, I receded at 23, but I was lossing density all over the top of my head diffuse thinning is worst type of balding.
 

BaldyBalderBald

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I had a receding hairline in my teens too. I was watching other guys' hairlines too.

But I wasn't plucking off hairs from different areas of their heads and comparing the thickness of hair shafts for miniaturization under magnification. That's what it really takes to spot early miniaturization.


Sorry to keep giving you crap about this but it's something that I feel strongly about it. IMO checking for miniaturization should be more understood and more common. There are exceptions to everything but IMO long-term balding is usually detectable many years before it gets visible. I think thousands of guys would be making better baldnesss treatment and hair transplant decisions if we all did more "early screening" for the problem. By the time it's visually noticeable at all, the process is already advancing past the most treatable stages.

The best time to fight baldness was back when our friends/family would have called us crazy to be thinking about it.

No need to apologize dude, we can have different point of view here, that's what makes it interesting
I started treatments right away but it didn't work at 100%...feels bad man
 

BaldyBalderBald

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@BaldyBalderBald What are you waiting for in 2018? It is a very promising year in the history of the male pattern baldness.

I don't know, i don't think we'll see any new treatments on market next year, but i expect some news about promising ones
Some real news about Follica would be nice, Brotzu maybe (Yeah i know, but why not), Results from Breezula Phase 2A, Seti/Fevi Proof of Concept, RCH-01 and Samumed SM04554, that's all my hope here, anything to get off finasteride at this point.

There's so much treatments in the pipeline, like we never had this past 20 years, so yeah 2018 could be huge, but i just don't think anything will be released...i wish i'm wrong tho.

Tsuji/Riken will continue his way to make it by 2020 i hope

You ? What makes you think this is gonna be a promising year ?

Edit : And i forgot soft JAK inhibitors Proof of Concept for Androgenetic Alopecia...this...this could be huge
 
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ZZmop

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I don't know, i don't think we'll see any new treatments on market next year, but i expect some news about promising ones
Some real news about Follica would be nice, Brotzu maybe (Yeah i know, but why not), Results from Breezula Phase 2A, Seti/Fevi Proof of Concept, RCH-01 and Samumed SM04554, that's all my hope here, anything to get off finasteride at this point.

There's so much treatments in the pipeline, like we never had this past 20 years, so yeah 2018 could be huge, but i just don't think anything will be released...i wish i'm wrong tho.

Tsuji/Riken will continue his way to make it by 2020 i hope

You ? What makes you think this is gonna be a promising year ?

Edit : And i forgot soft JAK inhibitors Proof of Concept for Androgenetic Alopecia...this...this could be huge

I thought Shiseido injections were to be commercially available in Japan in late 2018 or am I mistaken?
 

BaldyBalderBald

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I thought Shiseido injections were to be commercially available in Japan in late 2018 or am I mistaken?

Completely forgot that one, i was focused on Replicel, their split up is confusing, you're right tho, fingers crossed
Gonna book this trip to Japan
 
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