Stemson is going to use minipigs in the next stage of their hair cloning research

[froggy7]

Where is that quote from? I couldn't find it in their two recent updates.

AbbVie-backed Stemson snags $15M series A for hairy brush-up with Rogaine, Propecia

AbbVie wants more people to regain the pleasure of going to a barbershop or local hair salon, and the biopharma has a keen eye for aesthetics. | AbbVie's Allergan Aesthetics unit, famous for Botox, is among the investors pouring $15 million into Stemson Therapeutics, which sees itself a first...

www.fiercebiotech.com

 

[DuncanOP]

Doesn't his statement kind of imply that they're quite a bit further from human trials than one year?

I think his statement is a little ambiguous. "to complete the R&D". What do you mean with R&D? If it just refers to pre-clinicals, so yes, we are f***** and human trials won't start next year. (Unfortunately, I think this is the most possible thing he means. Because he said "We don’t know when exactly we’ll get into human clinical trials". I understanded it same as you).

But if "R&D" means to all research stages before the commercialization (including human trials, of course), then is possible to start human trials next year (but again, I think this is not the case).

 

[H]

I think his statement is a little ambiguous. "to complete the R&D". What do you mean with R&D? If it just refers to pre-clinicals, so yes, we are f***** and human trials won't start next year. (Unfortunately, I think this is the most possible thing he means. Because he said "We don’t know when exactly we’ll get into human clinical trials". I understanded it same as you).

But if "R&D" means to all research stages before the commercialization (including human trials, of course), then is possible to start human trials next year (but again, I think this is not the case).

Always expect delays...

 

[trialAcc]

Doesn't his statement kind of imply that they're quite a bit further from human trials than one year?

It definitely does not sound like human trials are right around the corner like they had implied last year, however to me when he says "a couple of years" it just implies the next year or two (2021/2022) to get themselves positioned for human trials. It sounds to me like they have had setbacks with the quality or longevity of the follicles with pig skin.

I'm not going to try and over analyze and condemn a company for taking the right approach to development of a medical process this complicated. Look at how many companies/people like Tsuji, Histogen or Samumed promise something magical only to fall silent and produce nothing at all of value. I'd rather have a company with prominent and respectable financial backers who allow them to just do their work based on it's merit rather then the need for flashy hype to raise capital.

 

[eeyore]

It definitely does not sound like human trials are right around the corner like they had implied last year, however to me when he says "a couple of years" it just implies the next year or two (2021/2022) to get themselves positioned for human trials. It sounds to me like they have had setbacks with the quality or longevity of the follicles with pig skin.

I'm not going to try and over analyze and condemn a company for taking the right approach to development of a medical process this complicated. Look at how many companies/people like Tsuji, Histogen or Samumed promise something magical only to fall silent and produce nothing at all of value. I'd rather have a company with prominent and respectable financial backers who allow them to just do their work based on it's merit rather then the need for flashy hype to raise capital.

Right, respect to Geoff for being transparent about that. My confidence that they'll deliver a cure is higher than it ever was before even if the timeline has been delayed.

 

[froggy7]

Right, respect to Geoff for being transparent about that. My confidence that they'll deliver a cure is higher than it ever was before even if the timeline has been delayed.

let them show the results of pre-clinical tests on pigs at the beginning, then they will get some credit of trust, so far they have shown nothing but hairy mouse

 

[MrV88]

Setback or delay? They sound more like they've realized that it maybe won't be possible at all and could take years instead of starting trials soon.

 

[froggy7]

Setback or delay? They sound more like they've realized that it maybe won't be possible at all and could take years instead of starting trials soon.

here we go more information will be in 2022, earlier I would not expect an update from them

 

[froggy7]

And how do you think they got investors ?
from “no progress”?they just carefull

correct me if I am wrong, but did the previous saviors of the bald people not get money for research and provided us absolutely nothing.....

 

[H]

correct me if I am wrong, but did the previous saviors of the bald people not get money for research and provided us absolutely nothing.....

Yes but those other ones weren't real researchers or companies they were fake researchers and companies and this is 2021 and back then was the middle ages with regards to tech and Stemson is all about family and chivalry and the others were about increasing human suffering and so on. Those are the responses your going to get let's just get it out of the way.

 

[froggy7]

Yes but those other ones weren't real researchers or companies they were fake researchers and companies and this is 2021 and back then was the middle ages with regards to tech and Stemson is all about family and chivalry and the others were about increasing human suffering and so on. Those are the responses your going to get let's just get it out of the way.

isn't Tsuji a scientist? also had a solution to the problem why no human trials yet? hamilton can write and say what he wants, I'm only interested in the result, when I see two pictures on one, a bald head and on the other the same head with hair, thick and shiny, then I will believe by the way, have any of you invested in cryonics?

 

[UnaSutherlands]

I hope everything will work out for them

 

[H]

isn't Tsuji a scientist? also had a solution to the problem why no human trials yet? hamilton can write and say what he wants, I'm only interested in the result, when I see two pictures on one, a bald head and on the other the same head with hair, thick and shiny, then I will believe by the way, have any of you invested in cryonics?

Nah I agree with you i just saying what others will

 

[trialAcc]

Setback or delay? They sound more like they've realized that it maybe won't be possible at all and could take years instead of starting trials soon.

It literally blows my mind that people can sit there and type things like this as the CEO is standing there with a fresh 15 million dollar check in his hand from biotech giants who are itching to partner with him.

Guys, use some common sense, please. I know many of you default to instant negativity as a means of existence, but realize that not everyone is trying to scam you into getting hyped over their over-promised product. This company has nothing to sell you, and wont have anything to sell you unless they are successful. This isn't a cream or lotion, it's literal organ cloning.

Just put it in the back of your mind and forget about it for a few years rather then arguing and debating over your opinions from a single sentence in a press release.

 

[froggy7]

It literally blows my mind that people can sit there and type things like this as the CEO is standing there with a fresh 15 million dollar check in his hand from biotech giants who are itching to partner with him.

Guys, use some common sense, please. I know many of you default to instant negativity as a means of existence, but realize that not everyone is trying to scam you into getting hyped over their over-promised product. This company has nothing to sell you, and wont have anything to sell you unless they are successful. This isn't a cream or lotion, it's literal organ cloning.

Just put it in the back of your mind and forget about it for a few years rather then arguing and debating over your opinions from a single sentence in a press release.

do not praise the day before the sun goes down, the fact that they have money is very good news, but not that much money the companies were losing, to be honest, I personally believe in the success of this company, but I'm far from optimistic, you have to be realistic and the facts are, Since we don't have a single proof of their technology, the mouse model literally means nothing to be honest, I personally hope that their treatment will be available in 2030 and it will be a full head of hair, not 100 additional hair, if it appeared earlier I would be positively surprised

 

[trialAcc]

do not praise the day before the sun goes down, the fact that they have money is very good news, but not that much money the companies were losing, to be honest, I personally believe in the success of this company, but I'm far from optimistic, you have to be realistic and the facts are, Since we don't have a single proof of their technology, the mouse model literally means nothing to be honest, I personally hope that their treatment will be available in 2030 and it will be a full head of hair, not 100 additional hair, if it appeared earlier I would be positively surprised

If you think the mouse model means nothing, you don't understand what's happening here. Same goes for Tsuji, that mouse model is not the same as regular hairloss mouse models where they just grow mouse hair on shaved mice. It's cloned human hair on the body of a nude mouse. Alexei (the cofounder who's science this is based on) was the first person to clone a human hair in a lab, period. This sets them apart from basically any other company/process ever except for Tsuji, but these guys are actually funded and organized.

Either way, I'm saying the exact same thing as you. I'm not telling people that this is the end of hairloss and to be overly optimistic. I'm just saying to stop wasting your time/effort debating the process based on single lines of text in an interview. I think Stemson has a really good shot of accomplishing what they set out to, which is to offer us unlimited hair in the future. That future isn't going to be in the next 5~ years though, so don't cling to the idea of them as being some savior to rescue you from your current situation.

 

[froggy7]

If you think the mouse model means nothing, you don't understand what's happening here. Same goes for Tsuji, that mouse model is not the same as regular hairloss mouse models where they just grow mouse hair on shaved mice. It's cloned human hair on the body of a nude mouse. Alexei (the cofounder who's science this is based on) was the first person to clone a human hair in a lab, period. This sets them apart from basically any other company/process ever except for Tsuji, but these guys are actually funded and organized.

Either way, I'm saying the exact same thing as you. I'm not telling people that this is the end of hairloss and to be overly optimistic. I'm just saying to stop wasting your time/effort debating the process based on single lines of text in an interview. I think Stemson has a really good shot of accomplishing what they set out to, which is to offer us unlimited hair in the future. That future isn't going to be in the next 5~ years though, so don't cling to the idea of them as being some savior to rescue you from your current situation.

I am counting on 2030

 

[JaneyElizabeth]

You guys are looking in all the wrong places. The key is increasing anagen to cis-female adult female norms which can be 3.33 times longer than for guys. So even if you get all of the follicles working, if they only last one year then it's never going to work in terms of "curing" baldness. Hair loss fertilizers don't work nor mad topicals with stacks of 23 ingredients. Estradiol mediates hair growth and hair recovery. So to the extent that AA's work for hair loss, it is because, say, bicalutamide increases estrogen levels by spoofing the system but without estradiol, it's like pushing on a string.

 

[froggy7]

You guys are looking in all the wrong places. The key is increasing anagen to cis-female adult female norms which can be 3.33 times longer than for guys. So even if you get all of the follicles working, if they only last one year then it's never going to work in terms of "curing" baldness. Hair loss fertilizers don't work nor mad topicals with stacks of 23 ingredients. Estradiol mediates hair growth and hair recovery. So to the extent that AA's work for hair loss, it is because, say, bicalutamide increases estrogen levels by spoofing the system but without estradiol, it's like pushing on a string.

so stemson wont be effective?

 

[JaneyElizabeth]

so stemson wont be effective?

I have very little but the past to base my prognosis on but this is sort of a running joke on HairLossTalk.com. None of these companies ever meet their schedules or there's always some article about proceeding to round two in May of 2026 or something like that and then they miss that date and fade away.

I just don't think pig hair would do it for me, either.