Under 25 And Balding, What Cures Are You Looking Forward To?

[Omega2327]

You obviously are young. A few years ago I also was very hyped and enthusiastic. The older you get, the more grounded you will become.

I believe in one company. Truly only one. If Tsuji wasn't around, then I would not be anywhere near as hopeful. I am not hyped because I'm young like you used to be. I'm hyped because I believe in one company's science. It's completely different.

 

[hanginginthewire]

I believe in one company. Truly only one. If Tsuji wasn't around, then I would not be anywhere near as hopeful. I am not hyped because I'm young like you used to be. I'm hyped because I believe in one company's science. It's completely different.

Your "hype" and your "belief" don't sound scientific.

It occurs to me that those of you who are so optimistic should absolutely relish questions and naysayers on these forums. If you think the science (and equally important - the path to market launch) is there, I would think you'd love to field questions, educate, see the fullhead lightbulb moment when young struggling guys realize you're right and realize there life is gonna change....

Instead there's all this recrimination and anger at people who question the favored orthodoxy. As a fallen Catholic atheist, the parallel to the insecurity of the "faithful" is striking. Just replace Christ with Tsuji. There's even that subtle condescension of the newly faithful: "I used to be like you man, bald, lost, wayward. But then I gave my heart to Tsuji bro and since then my life has completely turned around!" So you ask the obvious questions, start requesting some evidence, or point out the glaring inconsistencies in the dogma, or ask for tangible, material, real world evidence, and it won't be too long before the flock begins to resent your insistence on results and prefers if you stay silent.

Someone who "believes" in a given treatment should start a thread where they will answer any and all questions, where they will try to educate members however they can. Instead the quasi official threads for treatments are full of people asking questions, and the believers getting annoyed at the insolence and moving the goalposts for their purported timelines.

 

[The Baldy Man]

why not?

I will get pubes grafted onto my head (in the back, not the hairline) if my situation gets that desperate. No joke.

 

[The Baldy Man]

They've been researching antidepressants for many decades and we still don't have anything better than worthless crap that is not much better than placebo.

http://blogs.nature.com/news/2008/02/post_3.html
https://www.psychologytoday.com/blog/real-healing/201202/do-anti-depressants-really-work

More than 9 out of 10 antidepressant developments utterly fail ...


Big Pharma also has plenty of funding, still they don't manage to find a cure for depression.


The first few years it's going to be patented, so it will be outrageously expensive. It will be the cure for $$$ millionaires. the rich folks...

Well I can't speak for everyone, but just anecdotally for me personally, antidepressants made me 100 percent better no placebo. I was dealing with severe OCD and depression before going on them and I became much better in the following months. I stupidly decided I didn't need them and that they were placebo pills back in May and by June 21 I had a MASSIVE serotonin crash with brain fog and constant panic that required hospitalization in a mental ward for 10 days while they put me back on Prozac. Incidentally, I had started finasteride just a few weeks before the crash and I thought for a while that I was having mental sides from finasteride but now that I am back on Prozac I feel 100 percent better and no sides whatsoever.

 

[Christian Miller]

Eh, there is always a "but this is different because of x" story with the next big thing in fighting hair loss. At first I was euphoric about this but it sounds like science fiction to me now. Not to mention there is gonna be a period of at least couple of years of that technique becoming widely available and at acceptable prices, even if it works.

And how exactly can those companies provide estimations and timelines? You either have the treatment sorted out and only need to fix the formalities or you dont, in which case you have no idea if you ll ever get the product to the market. Those dates and years only serve for getting attention from public or investors, or to satisfy curious reporters.

Obviously there is some progress in r&d over the years, but people are f*****g tired of reading about dozens of "revolutionary breakthroughs" every week, and cures that are "just around the corner" since the 90-s. That Tsuji`s 2020 commercialization date will in 6 months turn into "final trials should start in Q3 2020". By 2019 they will be talking about 2025 as the magical year.

And those experiments on mice don`t mean sh*t. Has there ever been a failed experiment of any sort done on mice or rats?

First of all, let me clarify that I ain't hyped for any of these future treatments.
Nonetheless, most of your arguments are invalid.
A) Pharmaceutical and biotechnology companies are able to provide "estimations and timelines" due to the fixed protocol they all have to abide by. Every single such company can set timelines once preclinical trials turn out successful.
B) Tsuji's deed is publicly funded, by the Japanese government. It needs no private investment.
C) I wouldn't say they are really trying to advertize themselves.
D) 95% of new products fail at the preclinical research level, in which, most of the times, mice are involved. In clinical trials, there are no mice, just humans (after all!). Furthermore, the success rate of phase II clinical trials (the lowest of all such rates) is 30-40%, which means what really? That most of the new products fail at the preclinical research level. In a nutshell, not all new products work on mice.

You are right on two things, though.
1) Even if Organ Germ Technology works out, it won't be available en masse right away, and it's gonna be costly.
2) Postponements due to unforeseen roadblocks are a reality.

 

[Omega2327]

Your "hype" and your "belief" don't sound scientific.

It occurs to me that those of you who are so optimistic should absolutely relish questions and naysayers on these forums. If you think the science (and equally important - the path to market launch) is there, I would think you'd love to field questions, educate, see the fullhead lightbulb moment when young struggling guys realize you're right and realize there life is gonna change....

Instead there's all this recrimination and anger at people who question the favored orthodoxy. As a fallen Catholic atheist, the parallel to the insecurity of the "faithful" is striking. Just replace Christ with Tsuji. There's even that subtle condescension of the newly faithful: "I used to be like you man, bald, lost, wayward. But then I gave my heart to Tsuji bro and since then my life has completely turned around!" So you ask the obvious questions, start requesting some evidence, or point out the glaring inconsistencies in the dogma, or ask for tangible, material, real world evidence, and it won't be too long before the flock begins to resent your insistence on results and prefers if you stay silent.

Someone who "believes" in a given treatment should start a thread where they will answer any and all questions, where they will try to educate members however they can. Instead the quasi official threads for treatments are full of people asking questions, and the believers getting annoyed at the insolence and moving the goalposts for their purported timelines.

People on here ignore facts.... that's what frustrates me. It's rather hard to educate someone who does that.

 

[Christian Miller]

They've been researching antidepressants for many decades and we still don't have anything better than worthless crap that is not much better than placebo.

http://blogs.nature.com/news/2008/02/post_3.html
https://www.psychologytoday.com/blog/real-healing/201202/do-anti-depressants-really-work

More than 9 out of 10 antidepressant developments utterly fail ...


Big Pharma also has plenty of funding, still they don't manage to find a cure for depression.


The first few years it's going to be patented, so it will be outrageously expensive. It will be the cure for $$$ millionaires. the rich folks...

Well, I guess you do what you are accusing the optimists do of. Misinterpreting facts.
There is not one single study that disproves the antidepressants' efficacy on cases of severe depression.
Most meta-analyses point out that there is no evidence that antidepressants work clinically better than placebos on cases of mild and moderate depression. Still, the presumed placebo effect of antidepressants does have clinical significance.

Besides, as @Omega2327 aptly explained, what the heck do antidepressants have to do with hair loss?

 

[Christian Miller]

Where do you get your numbers from ? *lol*
More like 5%.

Prove me wrong!

 

[shookwun]

Most people who go on anti depressants are wrongly diagnosed.


A simple stupid questionnaire can apparently get you a prescription of zoloft.


Took that sh*t for three months and it did nothing. Coming off was a pain, not to mention my dick would not work at all while I was on. It was literally impossible to c*m.


Never fool around with that sh*t. We don't suffer from chemical imbalanced but anxiety and depression induced from baldness. Explain to me how that garbage has any benefit on our case?

What worked? A hair transplant
No more anxiety and depression


Your anxiety and depression is a comorbid result from baldness.

 

[Christian Miller]

http://medcitynews.com/2011/06/new-drug-failure-rates-rising-in-phase-ii-and-iii-clinical-trials/

18%

I pity you.
Moron, your original post says 5% and the proof is in my reply to you.
Pathetic!

I want a link to the original paper.
The ones the article has on don't work.

 

[That Guy]

Someone who thinks stem cell research is science fiction.... lmfao..

A lot of it still is, though.

Most of the big deal, theoretical uses for stem cells are still pre-clinical with hurdles both legal and scientific standing in the way from making it a reality. There are presently only 2 stem cell therapies in mainstream use, with bone marrow being by far the most common for the last 40 years.

Also you have no f*****g clue how much it's gonna cost and like any big purchase, you could set up a payment plan, start saving up for years, etc. if you want something bad enough, there are so many things you could do to make it financially feasible, especially when we are talking years in advance.

We can reasonably estimate that it will be a lot, though — given what they said in the interview and their proposed business model.

Secondly, the number of people who will be willing to go into that kind of debt for funding, especially when so many have student loans, mortgages, kids, etc. is very small.

But everyone should just forgo all those things in life and should have anticipated the day haircloning would be a reality because hair > life, right? Sorry, I don't buy it; most people outside of Japan, funding or no, are not going to pay all the expenses involved to get all their hair back. It's not like buying cheap pills, spray/foam, shampoos, or small-scale cosmetic surgeries.

Instead there's all this recrimination and anger at people who question the favored orthodoxy.

Someone who "believes" in a given treatment should start a thread where they will answer any and all questions, where they will try to educate members however they can.

It would help if most of these people were actually asking questions rather than being like Bimmler and making threads and posts to specifically sh*t on developing tech and people who support it.

9/10 naysayers online aren't naysaying because they have "questions", they're specifically looking for a lack of some detail or whatever to say "Yeah, see it's never happening". Like all the ppl who would NOT stfu about Tsuji and the "inductivity" problem. No matter how many times one says "Just wait, because they said in the interview that their research has shown the-"

"Noooope! Liars! Urgh! Aaaaah!" *autistic screeching*

and then Noisette gets an email back saying "Yeah, we found a method and the results are awaiting publication" lol

Most people around here are only interested in finding more ammo for their self-pity and doubt and will try their best to contradict even blatantly obvious facts.

 

[ForeverBald]

https://www.bio.org/sites/default/f...6-2015 - BIO, Biomedtracker, Amplion 2016.pdf
The success rate is about 63% in phase 1 and 30% in phase 2. F*** we're doom

 

[Christian Miller]

https://www.bio.org/sites/default/files/Clinical Development Success Rates 2006-2015 - BIO, Biomedtracker, Amplion 2016.pdf
The success rate is about 63% in phase 1 and 30% in phase 2. F*** we're doom

@Miguel, Miguelito, who's wrong now, b**ch?

 

[Christian Miller]

https://www.bio.org/sites/default/files/Clinical Development Success Rates 2006-2015 - BIO, Biomedtracker, Amplion 2016.pdf
The success rate is about 63% in phase 1 and 30% in phase 2. F*** we're doom

Well, instead of whining, read the f-ing paper.
You'll understand better why the rates are that low.
You, people, are pathetic!

 

[H]

Curious, if Tsuji isn't going to be available to the majority of us because of price alone why do we talk about it anyway its not going to be a viable option for most of us so its pointless to even speculate or pay attention to Riken. Okay so they succeed.. oh well, if most can't utilize the treatment what purpose does it serve to the masses of the concerned hair loss sufferers? None in my opinion.

 

[Christian Miller]

Curious, if Tsuji isn't going to be available to the majority of us because of price alone why do we talk about it anyway its not going to be a viable option for most of us so its pointless to even speculate or pay attention to Riken. Okay so they succeed.. oh well, if most can't utilize the treatment what purpose does it serve to the masses of the concerned hair loss sufferers? None in my opinion.

We know nothing, mate.
All we know is that hair regeneration is the most effective solution out of the bunch.
That' all!

 

[hanginginthewire]

A lot of it still is, though.

Most of the big deal, theoretical uses for stem cells are still pre-clinical with hurdles both legal and scientific standing in the way from making it a reality. There are presently only 2 stem cell therapies in mainstream use, with bone marrow being by far the most common for the last 40 years.



We can reasonably estimate that it will be a lot, though — given what they said in the interview and their proposed business model.

Secondly, the number of people who will be willing to go into that kind of debt for funding, especially when so many have student loans, mortgages, kids, etc. is very small.

But everyone should just forgo all those things in life and should have anticipated the day haircloning would be a reality because hair > life, right? Sorry, I don't buy it; most people outside of Japan, funding or no, are not going to pay all the expenses involved to get all their hair back. It's not like buying cheap pills, spray/foam, shampoos, or small-scale cosmetic surgeries.





It would help if most of these people were actually asking questions rather than being like Bimmler and making threads and posts to specifically sh*t on developing tech and people who support it.

9/10 naysayers online aren't naysaying because they have "questions", they're specifically looking for a lack of some detail or whatever to say "Yeah, see it's never happening". Like all the ppl who would NOT stfu about Tsuji and the "inductivity" problem. No matter how many times one says "Just wait, because they said in the interview that their research has shown the-"

"Noooope! Liars! Urgh! Aaaaah!" *autistic screeching*

and then Noisette gets an email back saying "Yeah, we found a method and the results are awaiting publication" lol

Most people around here are only interested in finding more ammo for their self-pity and doubt and will try their best to contradict even blatantly obvious facts.

Lol, what exactly is "autistic screeching" anyway?

Part of the reason we got the email on the "inductivity" issue is because people were beating the drum on getting an answer to that. I agree there's the odd Bimmler or whomever who are trolling but I think most here just want answers.

For myself I can't tell you the difference in my outlook when I feel more positive about upcoming treatments. If hair loss isn't (effectively) cured, I basically feel like my life is over. When I'm feeling better about a way out of this nightmare, my entire outlook on life improves a hundredfold. Melodramatic as f*** but that's pretty much how I feel. I bet many feel similarly, that's why we're here. And yet I've never been one to just cling to platitudes and well-wishes. If I ever developed cancer or some other serious illness, it would enrage me for people to cloak it in "positivity" or whatever. Nope, i want to see the scans. Let me look, I want to know. And so it is with hair loss. It's fine well and good to talk about upcoming treatments in some nebulous, feel good, we're gonna make it brahs! way. Many of us aren't satisfied with that.

Anyway, I've beat this horse. It just seems like when we go beyond the hopeful platitudes and start really examining a given treatments hurdles and challenges, it sounds like we are still pretty much fucked. But if we are its better to look it in the face. As I said, those of you who cheerlead for given treatments should be willing to supply facts and really should appreciate being able to means test your treatments. I fear some of you don't like the naysayers because it confirms your own questions and doubts.

 

[That Guy]

Curious, if Tsuji isn't going to be available to the majority of us because of price alone why do we talk about it anyway.

Because these forums are about discussing developing technologies, drugs, research, etc. and Tsuji's research is one of the most ground-breaking developments.

Lol, what exactly is "autistic screeching" anyway?

 

[shookwun]

 

[H]

Because these forums are about discussing developing technologies, drugs, research, etc. and Tsuji's research is one of the most ground-breaking developments.

But if it is too expensive for the mass we won't be able to utilize the fruits of his labor...at all.